Senior AI Engineer - Clinical Reasoning
NxT Level
Job Description
Job Description
Senior AI Engineer
Location: New York City
Work Style: Hybrid Onsite
Employment Type: Full-time
Focus: AI, LLMs, Clinical Reasoning, Evaluation, Retrieval, Applied ML
About Our Client
Our client is building AI technology with the mission of making high-quality healthcare more accessible, affordable, and scalable.
Their AI-powered clinical platform already supports millions of patient consultations, and the company is working toward scaling that impact significantly while continuing to improve clinical safety, reasoning quality, accuracy, and trust.
This is an opportunity to join a team building real-world clinical AI systems used by patients every day. The company operates in a live healthcare environment, giving the team a unique dataset and feedback loop to test, improve, and deploy AI systems in practical clinical care.
About the Role
Our client is hiring a Senior AI Engineer to help build the next generation of clinical AI systems.
This role blends research and engineering. The ideal candidate is not just running experiments or writing notebooks — they are building real systems that reason, retrieve evidence, evaluate performance, and improve over time.
You'll work on agentic reasoning, retrieval, evaluation infrastructure, model learning, and clinical decision support systems. The goal is to help every component of the AI platform become safer, more accurate, more useful, and more trustworthy with each iteration.
What You'll Do
Design and build agentic clinical reasoning systems
Develop AI architectures that support reasoning, reflection, verification, tool use, routing, uncertainty handling, and escalation
Build systems where specialized agents and models work together to support safe and reliable clinical decisions
Create evaluation platforms, rubrics, simulations, and experiments to measure AI performance in clinical use cases
Identify whether improvements should come from reasoning, retrieval, model behavior, data, or engineering changes
Apply methods such as fine-tuning, distillation, reinforcement learning, preference optimization, and prompt or system optimization
Build training data, feedback, reward, and experimentation pipelines
Develop search, ranking, retrieval, and grounding algorithms tied to trusted medical evidence and patient context
Improve retrieval systems based on their impact on downstream clinical decisions, not just document relevance
Own problems end-to-end, from framing and experimentation through shipping and measurement
Collaborate closely with engineering, clinical, product, and physician-scientist partners
What We're Looking For
Strong experience building real AI, ML, or LLM-powered systems
Deep experience in at least two of the following areas:
Agentic architectures, reasoning systems, and tool use
Model evaluation, experimentation, and rubric design
Model training, fine-tuning, distillation, or reinforcement learning
Search, ranking, retrieval, RAG, or grounding systems
Strong ML fundamentals, including training data, objectives, metrics, failure analysis, calibration, and validation
Ability to work in complex domains where ground truth is incomplete and expert opinions may differ
Strong engineering fundamentals with experience building production systems, not just research prototypes
Clear communication and strong collaboration across engineering, clinical, and product teams
Ability to think through business impact and prioritize technical work accordingly
Comfort operating with autonomy in a builder-first environment
Experience Profile
Successful candidates will typically have one of the following backgrounds:
Advanced degree in a quantitative, computational, scientific, or related discipline with 3+ years of highly relevant applied AI/ML or research experience
7+ years of relevant experience building and researching ML systems
Recent hands-on work with LLMs, generative AI, agentic systems, retrieval systems, or production AI infrastructure
Our client cares more about the depth and quality of your work than a specific credential or traditional career path.
Bonus Experience
Published research, patents, meaningful open-source contributions, or novel production ML systems
Experience building AI systems at an early-stage or high-growth company
Experience in healthcare, clinical AI, regulated industries, or safety-critical environments
Familiarity with clinical workflows, healthcare data, HIPAA, FHIR, EHR systems, or HL7
Experience with human-feedback systems, RLHF, simulations, or synthetic data generation
Experience with AI safety, bias detection, calibration, fairness, or model reliability
Why This Opportunity
Build AI systems that can meaningfully improve access to healthcare
Work on real clinical AI problems with real patient usage and feedback
Join a team focused on reasoning, retrieval, evaluation, safety, and trust
Work side by side with physician-scientists and experienced technical builders
Own high-impact AI systems end-to-end
Operate with autonomy in a fast-moving, builder-first environment
Contribute to technology designed to scale from millions of consultations to much larger clinical impact
Compensation & Benefits
Competitive salary
Meaningful equity with upside as the company grows
Comprehensive health benefits
High autonomy and ownership over important technical problems
Opportunity to build AI systems transforming healthcare at scale
Ideal Candidate Profile
The ideal candidate is a research-minded AI engineer who wants to build intelligent systems that work in the real world. They care deeply about reasoning quality, evaluation, safety, and measurable improvement — and they have the engineering ability to turn ambitious ideas into production systems.
This person is excited by the challenge of building clinical AI that can earn trust over time.
$128k - $252.5k
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