Principal Scientist, Biosensor Assay Development

The Allegro team is united by a clear purpose—advancing technologies that make the world safer, more efficient, and more sustainable. With over 30 years of experience in semiconductor innovation, we bring that purpose to life across every part of the business—from breakthrough product development and customer success to how we show up for each other and the communities we serve. Allegro MicroSystems is expanding its technology portfolio by integrating high‑precision semiconductor sensing with advanced biochemistry, developing a lab‑on‑chip solution for point‑of‑care diagnostics. We are seeking a Principal Assay Scientist to lead the biochemical development and application of our Giant Magnetoresistance (GMR) biosensor platform. This is a foundational role within a specialized internal venture, where you will be responsible for the "wet‑ware" and surface chemistry that allows our sensors to interface with complex biological systems. As a hands‑on leader, you will establish our Manchester‑based biochemistry lab, oversee the development of diverse assay formats, and work directly with global customers to transition their biological and diagnostic applications onto our sensing platform. What You Will Do Establish and oversee a new biochemistry R&D laboratory in Manchester—define SOPs, manage safety protocols, and lead a small, agile team. Lead the design and optimization of various assay formats, including sandwich and competitive architectures across targets (proteins, DNA, RNA) and sample matrices (whole blood, serum, saliva). Optimize functionalization of sensor surfaces—develop robust protocols for tethering capture molecules while minimizing non‑specific binding and ensuring reagent stability. Serve as the Lead Field Applications Scientist (FAS): support early‑adopter customers by creating proof‑of‑concept samples, validating use cases, and traveling to customer sites. Collaborate with microfluidic, packaging, and manufacturing engineers to ensure biochemical methods are compatible with high‑volume production and cartridge assembly processes. What You Will Need Ph.D. in Biochemistry, Bioengineering, Molecular Biology, or related field. 8‑12 years of experience in assay development within diagnostics or life‑sciences industry. Proven success taking an assay from concept to validated method. Deep expertise in immunoassays and/or molecular diagnostic techniques. Strong understanding of surface functionalization (e.g., silanes, PEGylation, or related chemistry). Experience with microfluidic systems or lab‑on‑chip platforms. Hands‑on entrepreneurial approach; comfortable with bench work, lab management, technical sales support, and high‑level strategy. Ability to bridge biochemistry and electronic engineering. Ready to travel up to 25% for customer integration and production bring‑up. Eligible applicants must reside in a state where Allegro currently has an office location: New Hampshire, Massachusetts, Texas, or Michigan. Equal Opportunity Allegro is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, physical or mental disability, national origin, veteran status, parental status, or any other basis covered by appropriate law. Allegro makes hiring decisions based solely on qualifications, merit, and business needs at the time. #J-18808-Ljbffr