Senior Director, Clinical Operational Excellence

Who we are:Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit  or follow us on X (formerly Twitter) or LinkedIn. How we work:PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.How you’ll make an impact:Define and implement the long-term vision for Clinical Operations Excellence, ensuring alignment with corporate objectives and regulatory standards.Partner with senior leaders in Clinical Development, Quality, Regulatory, and other functions to harmonize processes and elevate trial execution.Lead the design and deployment of scalable, standardized processes, tools, and KPIs across clinical operations.Oversee operational performance dashboards, risk management frameworks, and trial health reporting to ensure proactive issue identification and resolution.Champion continuous improvement initiatives that enhance trial efficiency, cost-effectiveness, and speed-to-market.Partner with Quality Assurance to ensure inspection readiness and adherence to compliance frameworks.Develop and implement frameworks to ensure adherence to regulatory requirements and Good Clinical Practice (GCP) guidelines. Ensure adherence to global regulatory requirements, ICH-GCP, and company SOPs.Develop training programs and support change management initiatives to embed best practices.Drive continuous process improvements to enhance operational efficiency, quality, and effectiveness in clinical oversight.Skills and experience you’ll bring:10+ years of experience in the biotech/pharmaceutical industry with direct experience in project management within Clinical OperationsProven track record in process improvement, clinical trial execution, and operational strategy.Experience with planning, management, and oversight of activities and deliverables within Clinical OperationsStrong understanding of clinical trial management, ICH-GCP, and regulatory complianceProven track record of managing multiple projects and/or programs concurrentlyExcellent analytical, problem-solving, and organizational skills.Strong communication and interpersonal skills with the ability to influence cross-functional stakeholders.Demonstrated ability to lead change and foster a culture of continuous improvement.Equal Employment OpportunityKymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.CompensationKymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.The anticipated base salary range for this role is $195,000 – $275,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.