Scientist I/II, LNP Formulations

Seeking a Scientist I/II specializing in Lipid Nanoparticle (LNP) Formulations to lead the design, execution, and analysis of experiments for next-generation LNP systems. This role focuses on developing, optimizing, and characterizing LNPs for nucleic acid delivery in a dynamic research setting. Responsibilities: Design and analyze experiments using DOE approaches to create and optimize innovative LNP formulations. Drive formulation innovation by selecting lipids, optimizing compositions, and evaluating process parameters. Conduct LNP screening and characterization, assessing size, PDI, encapsulation efficiency, stability, and performance. Utilize analytical and statistical methods to interpret complex data and inform formulation strategies. Collaborate with multidisciplinary teams to advance research and development programs. Document experiments thoroughly and communicate findings and recommendations to stakeholders. Troubleshoot formulation issues and enhance experimental workflows for continuous improvement. Support scale-up processes and technology transfer activities as required. Qualifications: PhD or MS in Chemistry, Pharmaceutical Sciences, Chemical Engineering, Materials Science, or a related discipline. Hands-on experience with LNP formulation development and optimization. Expertise in DOE methodologies and statistical experimental design. Proficiency in LNP screening and analytical techniques such as DLS, encapsulation assays, stability studies, and physicochemical characterization. Strong understanding of lipid-based delivery systems and formulation science. Demonstrated ability to work effectively in a fast-paced, team-oriented environment. Excellent problem-solving skills and capability to manage multiple priorities. Effective communication skills for presenting data and influencing technical decisions. #J-18808-Ljbffr ClinLab Solutions Group