Founding Backend & Infrastructure Engineer
$160k - $200kTrue Talent Solutions Partners
About the Role
Join an early-stage healthtech team building clinical AI systems for healthcare payments. You will own core backend infrastructure that processes complex healthcare data and supports clinical and financial workflows.
What You'll Do
Build and scale distributed backend systems for chart processing, claims, authorizations, denials, and payer and provider integrations.
Develop browser and computer-use automation to navigate electronic health record software and payer portals.
Design reliable infrastructure for scanned charts, PDFs, structured claims, unstructured notes, and operational data at scale.
Build orchestration, queuing, retry, and observability systems for long-running workflows across healthcare platforms.
Partner with research and product engineers to bring clinical intelligence capabilities into production and establish engineering patterns.
What We're Looking For
At least 3 years of backend software engineering experience, with a focus on infrastructure and complex systems.
Experience owning and scaling backend infrastructure at a technically complex company, such as in data infrastructure or fintech.
Strong Python, microservices, and distributed systems experience, including end-to-end system design and implementation.
Experience with production LLMs or machine learning models, data pipelines, workflow orchestration, or large, messy datasets.
Browser or computer-use automation and complex integrations experience are relevant.
Startup experience, comfort with fast-paced work and risk, and interest in an early-stage team are important.
A degree in computer science, mathematics, or a related field, or equivalent strong technical foundations.
Authorized to work in the United States. Visa sponsorship is not available.
Compensation & Benefits
Base salary: $160,000 to $200,000 annually. Visa sponsorship is not available.
Location
On-site in San Francisco, United States.
- fal is building the core platform that powers the company’s generative media ecosystem. We seek a founding backend platform engineer to own billing, pricing, accounts, access, API keys, and model discovery end-to-end. You’ll design APIs and data models, ensure correctness...Suggested
- Stealth Startup is seeking a Founding Senior Backend Engineer to shape core systems powering millions of AI-driven conversations. You’ll tackle real-time audio, telephony, and developer tooling, collaborating with the founding team from architecture to production. You...Suggested
- Zania Inc. is seeking a Founding Software Engineer (Mid-Senior) to help build the backend systems powering our agentic AI platform. This role focuses on scalable, secure services and petabyte-scale data pipelines, with high emphasis on reliability and security. You will...Suggested
- Backbone is building the clinical AI layer for healthcare payments. Founding Engineer, Backend & Infrastructure will own the systems that power Backbone’s clinical and financial workflows, including chart and claims data, authorization, denial handling, and payer/provider...Suggested
- Supio, headquartered in Seattle with an office in San Francisco, is building a new Compliance Platform. We are hiring a Senior Backend Engineer to design and implement the platform from the ground up, focusing on anonymization and secure access to PHI/PII for AI...SuggestedWork at office
- ...We are hiring a Founding Software Engineer in San Francisco. We are building a small, talent-dense... ...technical stack end-to-end, from core infrastructure and production systems to deployment... .... Architect, build, and scale core backend systems powering document intelligence...
- Prestige Ventures Inc. is seeking a generalist, high-agency backend engineer with 5+ years’ experience to build customer-facing products. You... ...-stage startup DNA, comfort with ambiguity, and strong collaboration with the founding team. #J-18808-Ljbffr Prestige Ventures Inc.
$200k - $300k
...Job Description About the Role Own the backend systems behind an AI assistant that communicates... ...through text, email, and phone. As a hands-on founding engineer, you will design, build, and operate reliable infrastructure for message delivery, long-running agent tasks...Immediate start$25k
...miss those nuances. They're hiring 3 founding engineers. What you'll own A production agent from... ...when the numbers disagree The backend and infra that get the product from pilot... ...Document AI, computer vision, MCP or agent infrastructure What’s in it for you $200k-$300k base...Full timeRemote workVisa sponsorship$200k - $300k
...the world. The role You’ll own the infrastructure Pally runs on. People text Pally... ...every week. This is a hands-on engineering role. You’ll design it, build it,... ...own everything you ship. You want founding-team scope. You’ll set the backend bar for Pally and help hire the engineers...Full time- Who we areAbout StripeStripe is a financial infrastructure platform for businesses. Millions of companies—from... ...information on our team matching process can be found here.What you’ll doWe're looking for Backend Engineers who want to make an impact on managing money at...Internship
$225k - $275k
...-caliber team building AI-powered video technology. As a founding backend engineer, you will lead the design of core systems and set a high... ...scalable backend systems that power AI video creation. Build infrastructure for agentic workflows, video generation pipelines,...Full time- True Talent Solutions Partners is seeking a founding backend engineer to design core systems for an AI-powered video platform. You will lead scalable backend development, own distributed architecture, and set engineering standards in a fast-growing startup On-site in San...
- ...building an AI operating system for commercial lending. We are hiring 3 founding engineers to own end-to-end features from the borrower portal to live data reconciliation. You’ll work on production-grade backend and infra, computer vision for financial statements, and turning...
- Onos Health Inc. is seeking an experienced engineering leader in San Francisco to own a significant portion of the platform. You will work... ...lead a growing engineering team while collaborating with the founding team. The role focuses on architecting AI/ML workflows,...
$170k - $243k
Senior Backend Engineer, Compliance Platform Seattle Hybrid / San Francisco Hybrid Software Engineering... ...every personal injury matter. As the founding backend engineer, you will design and... ...Strong experience with cloud data infrastructure — S3, relational databases, and the...Full timeWork at officeRemote workFlexible hours$180k - $240k
NQB8, a national security company incubating ambitious startups in San Francisco, is seeking an exceptional backend software engineer. You are among the top 10% of developers you have ever worked with and thrive in a founder-led, high-velocity environment. This in-person...- ...systems with adaptive, learning software. Founded in early 2024, Serval is already trusted... ...IT, HR, Finance, Security, Legal, and Engineering. Our mission is to eliminate repetitive,... ...Overview As a Senior Software Engineer, Backend at Serval, you will play a pivotal role...
- Mercator in San Francisco is seeking its first product engineer to architect and build the core systems powering a simulation-driven product... ...workflows, translate them into system design, and own the backend logic that turns complex scenarios into clear, actionable outcomes...
- ...and graceful fallbacks. Define all cloud resources in Pulumi; deploy through GitHub Actions. Optimize serverless GPU functions for cold-start, cost, and concurrency. Set SLOs, add Datadog alerts, and maintain clear runbooks. Focus: 60% backend, 40% infrastructure Tranzeal
- The RoleRaydar is recruiting for this role on behalf of our client. Own production infrastructure that supports large-scale automated data collection from websites that try to restrict it. The work spans network routing, session handling and troubleshooting stubborn intermittent...
- Pally is hiring a senior to staff level backend engineer to own and scale the infrastructure that powers a consumer AI assistant. You’ll design, build, run, and be paged for reliability as traffic grows weekly. Expect hands-on work across messaging pipelines, agent runtimes...
$170k - $205k
...energy and intelligence. As the only vertically integrated AI infrastructure company built from the ground up, we own and operate each... ...us at Crusoe.About This Role:We are seeking a Senior Backend Software Engineer to join the Core Backend team within Cloud Customer...Temporary work$200k - $260k
...Job Description Job Description Founding Security Infrastructure Engineer Company: Confidential — customizable AI phone sales agents Location: San Francisco, CA (hybrid, 3-4 days per week in office) Compensation: $200,000 - $260,000 + competitive equity...Full timeH1bWork at officeVisa sponsorship3 days per week- Salesforce is seeking a Software Engineer - GovCloud for the Public Cloud engineering team. You will design, develop, and optimize distributed... ...delivery, and debt management. A related technical degree and 3+ years of backend experience are required. #J-18808-Ljbffr Salesforce
- A leading gaming technology company is seeking a Senior Backend Engineer to enhance their cloud development practices and build scalable services. You will significantly impact gaming experiences while collaborating with diverse teams. A strong background in backend systems...Remote jobWork at office
- Cisco Systems, Inc. in San Francisco is seeking a backend-focused engineer to architect and scale cloud video streaming, exports, and cloud storage, with opportunities to contribute across the full stack. The role emphasizes high-availability systems on AWS, API design...Remote job
$180k - $250k
...teams across the United States to help them hire. Founding Full-Stack Engineer Location San Francisco, CA Fully... ...software engineering, with strong ownership across backend, frontend, infrastructure, and AI-powered systems. Employment Type Full...Full timeWork at officeImmediate startRemote workRelocation packageShift work- Leadout Capital is seeking a Software Engineer for GovCloud in San Francisco. You will help design, build, and operate a large-scale distributed backend platform with a strong focus on reliability, security, and AI-enabled tooling. You will work across AWS/GCP/Azure-like...
- ...into connected data for AI agents. You will design and build backend systems to ingest, organize, connect, and retrieve enterprise... ...ensuring accuracy and context for AI tasks. This role blends backend engineering, data architecture, and experimentation. #J-18808-Ljbffr Mason...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Founding Backend & Infrastructure Engineer. Be the first to apply!
- senior backend developer San Francisco, CA
- back-end developer San Francisco, CA
- backend software engineer San Francisco, CA
- remote back end developer San Francisco, CA
- lead infrastructure engineer San Francisco, CA
- infrastructure developer San Francisco, CA
- infrastructure engineering manager San Francisco, CA
- data infrastructure engineer San Francisco, CA
- remote infrastructure engineer San Francisco, CA
- entry level infrastructure engineer San Francisco, CA




