Translational Genetics & Medicine Lead - Target Discovery to Phase 2
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals seeks a physician-scientist to guide translational research from lead target discovery to early clinical trials (Ph1/2) in Cambridge, MA. You will integrate medicine with human genetics data and collaborate across translational biology, clinical research, and data science to prioritize targets and biomarkers. The role emphasizes building external relationships, trial design input, and effective scientific communication to advance RNAi-based therapeutics. #J-18808-Ljbffr Alnylam Pharmaceuticals
$212k - $333.19k
...DescriptionSenior Director, AIRx Discovery Biology Lead Takeda Research is... ...differentiated medicines to the clinic at... ...the mechanistic and translational foundation that... ...guiding the team from target hypothesis to clinical... ...citizenship status, genetic information or...TargetMinimum wageLocal areaRemote work$215k - $245k
Principal Scientist, Translational Data Science... ...Parabilis Medicines is a clinical-... ...important targets long considered... ...The company's lead investigational... ...activities and Phase 1/2 development.... ...insights from discovery into development... ...human genetics, tumor genomics...TargetShift work$202.3k - $273.7k
...scientist to join the Translational Research Group... ...guiding the discovery, validation,... ...therapeutic targets. You will join... ...and human genetics to new medicines. Our Research... ...programs from lead target identification... ...-stage (Ph1/2) clinical... ...identification through Phase 2 clinical...TargetFull timeTemporary workLocal areaFlexible hours$167k - $286k
...Medical Affairs Lead Cambridge, MA, United... ...potential of RNA medicines to transform... ...insights in human genetics to deliver scientific... ...toolkit of RNA-targeting modalities... ...across platform and discovery-stage programs at... ...Platform Discovery, Translational, Corporate Communications...TargetFull timeContract workTemporary workSummer workWork at officeLocal area$196.7k - $353.4k
...leader to serve as Senior Director, Translational Medicine Lead - Autoimmune. This individual will lead... ..., proteomics, serology, HLA/genetic analysis, and tissue-based approaches... ...response frameworks connecting dose to target engagement, immune-cell effects, disease...TargetPermanent employmentFull timeWork at officeWork from home- ...deliver innovative medicines and solutions... ...s Respiratory Discovery Research team,... ...Team (DDT) Lead is tasked with... ...to develop translational immunology insights... ...role of target pathways. The... ...projects across all phases of drug... ...peptides, and genetic medicine therapies...TargetLocal area
$195k - $239k
...vivo screening to unlock tissue-targeted medicines and organism-scale models of... ...computational models, which leads to better drug designs,... ...leadership of cross-functional drug discovery teams advancing lead... ...capabilities, as needed.Lead 1-2 cross-functional drug discovery...Target$156.18k - $189.25k
...deliver innovative medicines to prevail over... ...responsible for the discovery and development... ...focus on novel targets and pathways for... ...discovery through translational and early clinical... ...expertise, biology and leading academic research... ...expression, genetic information,...TargetHourly payFull timeSummer workLive inLocal areaRemote workFlexible hours$177k - $278.08k
...differentiate our drug discovery capabilities. This... ...capabilities, leading technical... ...and the ability to translate emerging technologies... ...including areas such as target identification and... ...status, genetic information or characteristics... ...innovation in medicine. Here, everyone matters...TargetMinimum wageFull timeWork at officeLocal areaWorldwide2 days per week3 days per week$114.1k - $211.9k
...scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker... ...strategies from target validation through development... ...Sciences, Translational Medicine, and Biomarker Development... ...biomarker strategy, biomarker discovery, or drug development...TargetFull timeLocal areaFlexible hours- ...Principal Scientist/Associate Director to lead a small group of biologists with... ...proteomics and imaging technologies to enable target discovery and validation across disease areas.... ...leadership, mentoring matrix teams, and shaping translational profiling capabilities using imaging,...Target
- ...Director of Global Proteomics to lead a wet-lab proteomics team within the Discovery Proteomic Platforms group. You will... ...across multiomics to guide target identification and therapeutic optimization... ..., and Neuroscience, and the translation of complex data into actionable...Target
- ...expertise in Innovative Medicine and MedTech, we are... ...merit. Job Function: Discovery & Pre-Clinical/Clinical... ...Development Job Sub Function: Translational Discovery &... ...Immunology Our Immunology team leads in the development of... ...these hypotheses into target product profiles,...Target
- Principal Scientist, Translational Computational... ...innovative medicines to prevail... ...lifecycle of drug discovery and... ...the path from target validation and... ...BMS's industry-leading early-stage clinical... ...our own early-phase trials, spanning... ...omics, genetic evidence, perturbation...Target
$117k - $195.13k
...expertise in Innovative Medicine and MedTech, we are... ...merit. Job Function: Discovery & Pre-Clinical/Clinical... ...Development Job Sub Function: Translational Discovery &... ...Our Immunology team leads in the development of... ...these hypotheses into target product profiles, study...TargetContract workLocal areaImmediate start$179k - $236.5k
...transformative drug targets and first-in-class medicines. The company’s... ...collaborations with leading pharmaceutical partners... ...Lead to lead our discovery program in Women’s... ...interpreting results, and translating them into program... ...multi-omic or genetic data into experimental...Target$110k - $160k
...healthcare incubator. From discovery to delivery,... ...-based modalities targeting tissues beyond the... ...biological and genetic evidence but have... ...focus offers strong translatability from animal models... ...data that drive lead selection and optimization... ...field, with 2-5 years of...TargetFull timeShift work- ...developing precision medicines utilizing its... ...traditional drug discovery, as well as current AI-based target-centric drug discovery... ...advancing its lead program, ACR-368 (... ...potentially registrational Phase 2 trial for EC. The... ..., Biology, Translational Science, and DMPK/...Target
$310k - $400k
...committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision,... ...efficient single base changes, at targeted genomic sequences, without... ...projects across all phases of drug discovery.Proven track record of successful...TargetFull time$177k - $278.08k
...choices that inform the target product profile and... ...You Will Contribute Lead commercial scenario planning... ...assumptions, and translate complex scientific and... ...leading innovation in medicine. Here, everyone matters... ...disability, citizenship status, genetic information or...TargetMinimum wageFull timeLocal areaWorldwide$141.08k - $235.13k
...delivering new medicines for people living... ...DMPK Drug Discovery Modeling will serve... ...-making from target validation through... ...opportunity to lead key activities... ...and translational models (PBPK, IVIVE... ...optimization to Phase I clinical studiesStrong... ..., disability, genetic information (...TargetFull timeLocal areaRelocation package$108k - $128k
...Scientist Parabilis Medicines is a clinical-... ...important targets long considered undruggable... .... The company's lead investigational medicine... ...may help translate the mechanism toward... ...transduction, or related genetic approaches to... ...in oncology drug discovery is strongly preferred...TargetShift work$229.8k - $402.8k
...lives. We develop medicines, intelligent devices... .... You will lead global clinical development... ..., including target product profiles,... ...Safety, Biostatistics, Translational Medicine, Medical... ...leading global Phase 2/3 or registrational... ...dedicated to Sparking Discovery and Elevating...TargetFlexible hours3 days per week$240k - $255k
...of novel disease targets – working at the... ...convergence of human genetics, best-in-class... ...design, and precision medicine. We are... ...) disorders. Our lead antibody program... ...stakeholders, including Translational Medicine,... ...conducting a stakeholder discovery session as they...TargetFull time$200.39k - $250.33k
...We’re pioneers in RNA-targeted medicines, and our platform... ...to revolutionize drug discovery and transform lives for... ...marketed medicines and a leading pipeline in neurology... ...it is moving and translating that into a differentiated... ...with biology, human genetics, and drug discovery...TargetRemote work$260.3k - $409.7k
...Clinical Director) in Translational Medicine/Early Clinical... ...collaboration with our discovery scientists and... ...of novel targets by partnering with... ...preclinical stage through Phase 1 studies of safety... ..., to Phase 2 studies demonstrating... ...strategyTaking a lead role in developing...TargetFull timeFor contractorsLocal areaWorldwideFlexible hours$260.3k - $409.7k
...PositionTranslational Medicine is responsible... ...with Discovery Sciences and late... ...and/or clinical translational research and a... ...Pharmacology testing (Phase 1), and... ...Concept (Phase 2).Development of... ...identification of novel targets by partnering... ...plans for Lead Optimization programs...TargetFull timeFor contractorsLocal areaWorldwideFlexible hours- ...Vice President of Translational Medicine. This is a senior... ...scientific, drug discovery and corporate... ...disease areas, drug targets, medicine profiles, and leading early translational... ...including human genetics, human target... ...leadership of Quotient’s Phase 1/2 clinical trials;...Target
$142.5k - $256.5k
...join the Antibody Discovery team within Therapeutics... ...Scientist will lead integrated... ...therapeutic-area research, target and antigen... ...technologies and translate relevant advances... ...to reimagine how medicines are created and delivered... ...veteran status, genetic information, sexual...TargetPermanent employmentFull timeWork from home- ...This individual will lead critical strategic... ...range forecasting, target product profile... ...and the ability to translate complex market dynamics... ...week; or select 2. On-Site: work five... ...disability, veteran status, genetic information, sexual... ...transformative medicines for people with...TargetRemote workFlexible hours2 days per week
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