Translational Genetics & Medicine Lead - Target Discovery to Phase 2
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals seeks a physician-scientist to guide translational research from lead target discovery to early clinical trials (Ph1/2) in Cambridge, MA. You will integrate medicine with human genetics data and collaborate across translational biology, clinical research, and data science to prioritize targets and biomarkers. The role emphasizes building external relationships, trial design input, and effective scientific communication to advance RNAi-based therapeutics. #J-18808-Ljbffr Alnylam Pharmaceuticals
$212k - $333.19k
...DescriptionSenior Director, AIRx Discovery Biology Lead Takeda Research is... ...differentiated medicines to the clinic at... ...the mechanistic and translational foundation that... ...guiding the team from target hypothesis to clinical... ...citizenship status, genetic information or...TargetMinimum wageTemporary workLocal areaRemote work$202.3k - $273.7k
...scientist to join the Translational Research Group... ...guiding the discovery, validation,... ...therapeutic targets. You will join... ...and human genetics to new medicines. Our Research... ...programs from lead target identification... ...-stage (Ph1/2) clinical... ...identification through Phase 2 clinical...TargetFull timeTemporary workLocal areaFlexible hours$215k - $245k
...About Parabilis Medicines Parabilis... ...important targets long considered... ...The company's lead investigational... ...leader within Translational Medicine responsible... ...and Phase 1/2 development.... ...insights from discovery into development... ...Integrate human genetics, tumor genomics...TargetShift work$167k - $286k
...Medical Affairs Lead Cambridge, MA, United... ...potential of RNA medicines to transform... ...insights in human genetics to deliver scientific... ...toolkit of RNA-targeting modalities... ...across platform and discovery-stage programs at... ...Platform Discovery, Translational, Corporate Communications...TargetContract workTemporary workSummer workWork at officeLocal area$196.7k - $353.4k
...leader to serve as Senior Director, Translational Medicine Lead - Autoimmune. This individual will lead... ..., proteomics, serology, HLA/genetic analysis, and tissue-based approaches... ...response frameworks connecting dose to target engagement, immune-cell effects, disease...TargetPermanent employmentFull timeWork at officeWork from home- ...deliver innovative medicines and solutions... ...s Respiratory Discovery Research team,... ...Team (DDT) Lead is tasked with... ...to develop translational immunology insights... ...role of target pathways. The... ...projects across all phases of drug... ...peptides, and genetic medicine therapies...TargetLocal area
$138.39k - $207.59k
...within oncology and/or translational research and have... ...team of translational medicine leads supporting our exciting... ...the pre-clinical Discovery, Early Clinical Development... ...and early clinical phase engagement.... ...across a wide variety of targeted therapies. To this end...TargetHourly payFull timeTemporary workWorldwide$110k - $140k
...About Parabilis Medicines Parabilis Medicines... ...important targets long considered undruggable... .... The company's lead investigational... ...Scientist to join our Hit Discovery team, reporting to... ...transcription/translation workflows, and... ...systems and genetic-code expansion enabling...TargetShift work$120k - $180k
...possible to deliver medicines that address critical... ...bringing together a target-centric approach, a toolbox... ...to support target discovery, translational biology, biomarker... ...Biology, Bioinformatics, Genetics, Immunology, Systems... ...related discipline. 2+ years of experience...Target$195k - $239k
...vivo screening to unlock tissue-targeted medicines and organism-scale models of... ...computational models, which leads to better drug designs,... ...leadership of cross-functional drug discovery teams advancing lead... ...capabilities, as needed.Lead 1-2 cross-functional drug discovery...Target$114.1k - $211.9k
...scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker... ...strategies from target validation through development... ...Sciences, Translational Medicine, and Biomarker Development... ...biomarker strategy, biomarker discovery, or drug development...TargetFull timeLocal areaFlexible hours$110k - $160k
...healthcare incubator. From discovery to delivery,... ...-based modalities targeting tissues beyond the... ...biological and genetic evidence but have... ...focus offers strong translatability from animal models... ...data that drive lead selection and optimization... ...field, with 2-5 years of...TargetFull timeShift work$100k - $181.5k
...first-in-class medicines and transformative drug targets. The company’s... ...collaborations with leading pharmaceutical... ...and support discovery efforts in projects... ...drug discovery translational biology. The... ..., genetic) and generate novel... ...strongly preferred 2+ years (Scientist...Target$310k - $400k
...committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision,... ...efficient single base changes, at targeted genomic sequences, without... ...projects across all phases of drug discovery. Proven track record of successful...TargetFull time- ...dedicated to drug discovery, clinical development... ...and pain. Our Phase 3 azetukalner program... ...from our Phase 2 X-NOVA clinical trial... ...heritage in human genetics, deep... ...selective ion channel targeting. We continue to advance... ...country language(s), translations and regulatory...TargetTemporary workWork at office2 days per week
$141.08k - $235.13k
...delivering new medicines for people living... ...DMPK Drug Discovery Modeling will serve... ...-making from target validation through... ...opportunity to lead key activities... ...and translational models (PBPK, IVIVE... ...optimization to Phase I clinical studiesStrong... ..., disability, genetic information (...TargetFull timeLocal areaRelocation package$142.22k - $172.34k
...deliver innovative medicines to prevail over... ...responsible for the discovery and development of... ...scientists focus on novel targets and pathways for... ...discovery through translational and early clinical... ..., biology and leading academic research... ...the Life Sciences 2+ of academic and...TargetHourly payFull timeContract workSummer workLive inRemote workFlexible hours$154.5k - $202k
...Advancements in AI and drug discovery are creating more... ...limit the number of new medicines that can reach patients... ...About the Role As Lead Tech Recruiter, you will... ...events relevant to our target candidate pools to build... ...orientation, age, disability, genetic information, marital...TargetFull timeWork at officeLocal areaRelocation3 days per week$229.8k - $402.8k
...lives. We develop medicines, intelligent devices... .... You will lead global clinical development... ..., including target product profiles,... ...Safety, Biostatistics, Translational Medicine, Medical... ...leading global Phase 2/3 or registrational... ...dedicated to Sparking Discovery and Elevating...TargetFlexible hours3 days per week- ...identification of novel disease targets – working at the convergence of human genetics, best-in-class... ..., and precision medicine. We are pioneering... ...&I) disorders. Our lead antibody program (... ...team through all phases of clinical... ...Experience with phase 1/2 clinical studies is...TargetFull timeFor contractors
$122.25k - $176.58k
...accelerate the path from discovery to patient impact.... ..., part of the Target, Disease, and Systems... ...first-in-class medicines to patients. Our approach... ...to creatively lead projects and coordinate... ...biology.At least 2 years of post-... ...cellular or blood trait; genetic information (...TargetFull time$109.2k - $174.6k
...antigens across discovery programs. This is... ...alone biologics, targeting modules, and components... ...the ability to translate experimental... ...aspired to build the leading mRNA technology... ...to reimagine how medicines are created and delivered... ...veteran status, genetic information,...TargetFull timeWork from home- ...In Vivo Pharmacology & Translational Biology Location:... ...Biosciences and help lead our efforts to develop transformative genetic medicines. We are seeking an experienced... ..., transgene and target protein expression, and... ...disease, or drug discovery/development setting....TargetFull time
$260.3k - $409.7k
...Clinical Director) in Translational Medicine/Early Clinical... ...collaboration with our discovery scientists and... ...of novel targets by partnering with... ...preclinical stage through Phase 1 studies of safety... ..., to Phase 2 studies demonstrating... ...strategyTaking a lead role in developing...TargetFull timeFor contractorsLocal areaWorldwideFlexible hours$177k - $294.8k
...We unite caring with discovery to help make life better... ...life-changing medicines, strengthen how health... ...is a clinical-stage genetic medicines company on... ...single-course cure. Its lead programs target PCSK9 and ANGPTL3 to... ...trials across multiple phases of developmentDeep understanding...TargetFlexible hours$200k - $240k
...Description About Parabilis Medicines Parabilis... ...biologically important targets long considered undruggable... .... The company's lead investigational medicine... ...to driving the Discovery programs forward that... ...focused on science as it translates to patient impact....TargetShift work$260.3k - $409.7k
...PositionTranslational Medicine is responsible... ...with Discovery Sciences and late... ...and/or clinical translational research and a... ...Pharmacology testing (Phase 1), and... ...Concept (Phase 2).Development of... ...identification of novel targets by partnering... ...plans for Lead Optimization programs...TargetFull timeFor contractorsLocal areaWorldwideFlexible hours$142.5k - $256.5k
...join the Antibody Discovery team within Therapeutics... ...Scientist will lead integrated... ...therapeutic-area research, target and antigen... ...technologies and translate relevant advances... ...to reimagine how medicines are created and delivered... ...veteran status, genetic information, sexual...TargetPermanent employmentFull timeWork at officeWork from home$310k - $340k
...Description About Parabilis Medicines Parabilis... ...important targets long considered undruggable... ...medicines. The company's lead investigational medicine... ...of the company's early discovery efforts, which span... ...focused on science as it translates to patient impact....TargetFull timeShift work$165k - $200k
...Description About Parabilis Medicines Parabilis... ...biologically important targets long considered undruggable... .... The company's lead investigational medicine... ...to the VP of Discovery DMPK, you will serve as... ...focused on science as it translates to patient impact....TargetShift work
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