Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Clinical Research Associate - CNS (US, Midwest)

$97k - $193k
Full-time

Worldwide Clinical Trials

Join a global Contract Resource Organization (CRO) where innovation meets purpose. At Worldwide Clinical Trials , we're driven by a shared commitment to improving lives through high-quality clinical research. Our teams are empowered to think creatively, take ownership, and deliver meaningful work that helps bring life-changing therapies to patients around the world.

With more than 4,000 professionals across the globe, we foster a collaborative and inclusive environment where diverse perspectives are valued, growth is encouraged, and every contribution makes an impact. Whether you're building your career or bringing years of experience, you'll have the opportunity to learn, grow, and help shape the future of clinical research.

Make an Impact as a Senior CRA at Worldwide

As a Senior CRA, you’ll play a critical role in ensuring clinical studies are conducted with the highest standards of quality, patient safety, and regulatory compliance. Your expertise will help drive the successful execution of studies from site qualification through closeout, supporting the delivery of reliable data that advances clinical research.

In this role, you'll serve as a trusted partner to investigative sites, study teams, and sponsors, building strong relationships while providing leadership, guidance, and oversight across clinical trial activities. You’ll have the opportunity to influence study success through proactive monitoring, site management, and collaboration with global teams.

Your contributions will directly support high-quality study delivery by ensuring protocol adherence, regulatory compliance, timely data collection, and effective site performance throughout the clinical trial lifecycle.

Where You'll Work

This is a home-based Clinical Research Associate role supporting sites across the Midwest of the United States. Candidates must reside within the territory to effectively support site visits and study activities. You will collaborate with sites, sponsors, and global study teams while traveling to investigative sites approximately 8-10 days per month.

To best support our sites, we're seeking candidates who are based in the Midwest of the United States. Travel will primarily be regional, with occasional travel to support sites in other locations as needed.

What You'll Do

  • Manage clinical research activities at investigative sites participating in Worldwide clinical studies.
  • Identify and assess potential research sites to support successful study execution.
  • Coordinate study start-up activities, including collection of regulatory documentation and support of contract and budget processes.
  • Conduct all types of monitoring visits: Pre-Site Selection Visits (PSSVs), Study Initiation Visits (SIVs),Interim Monitoring Visits (IMVs) and Closeout Visits (COVs).
  • Train site personnel on protocol requirements, data collection processes, and safety reporting expectations.
  • Monitor site performance and provide ongoing support throughout study maintenance activities.
  • Ensure compliance with informed consent requirements, safety reporting obligations, and applicable regulatory standards.
  • Partner with sites and study teams to drive data quality, participant safety, and overall study success.
  • Support site closeout activities and ensure study requirements are completed at the conclusion of the trial.

What You'll Bring

  • Bachelor's Degree or a Nursing Degree, along with 5+ years as a regional, traveling Clinical Research Associate.
  • Required experience monitoring CNS clinical trials.
  • Requires travel within the specified region; 8 – 10 DOS monthly
  • Experience in full-service monitoring preferred.
  • Strong knowledge of clinical trial processes, site management, and regulatory requirement

Discover the Difference

We love knowing that someone is going to have a better life because of the work we do. Discover the Difference at Worldwide Clinical Trials. Explore additional opportunities on our careers page, visit , or connect with us on LinkedIn .

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.

The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):
United States of America - $97,000.00 - $193,000.00


The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.

Worldwide is an equal opportunity employer that is committed to enabling professionals from all backgrounds and experiences to succeed and, to that end, we prioritize attracting diverse talent and cultivating an inclusive environment that encourages collaboration and creativity. We know that when our employees feel appreciated and included, they can be more creative, innovative, and successful. We’re on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We provide equal employment opportunities to all employees and applicants regardless of race, color, ethnicity, ancestry, religion, national origin, gender, sex, gender identity or expression, sexual orientation, age, citizenship, marital or parental status, disability, military status, or other class protected by applicable law .

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Clinical Research Associate - CNS (US, Midwest) in Minnesota vacancy
  • $97k - $193k

     ...Worldwide Clinical Trials seeks a Senior Clinical Research Associate to manage investigative sites across the Midwest, overseeing study execution from qualification through closeout. The...  ...adherence, and data quality while supporting CNS clinical trials. Responsibilities... 
    Senior
    Interim role
    Worldwide

    Worldwide Clinical Trials

    Minnesota
    13 hours ago
  • $97k - $193k

     ...Worldwide Clinical Trials seeks a Senior Clinical Research Associate to manage oncology clinical trials across Midwest investigative sites. The role involves site qualification, monitoring visits, protocol compliance oversight, and study execution from initiation through... 
    Senior
    Interim role
    Worldwide

    Worldwide Clinical Trials

    Minnesota
    13 hours ago
  • $97k - $193k

     ...Senior Clinical Research Associate position managing research activities at clinical trial sites in CNS/Psychiatry studies. Responsibilities include site selection, study initiation, regulatory compliance, and site closeout across remote and regional in-person activities... 
    Senior
    Work at office
    Remote work

    Worldwide Clinical Trials

    Minnesota
    a month ago
  • $97k - $193k

     ...Worldwide Clinical Trials seeks a Senior Clinical Research Associate to manage oncology trial sites across the Midwest and Central regions. The role involves site selection, study initiation, regulatory compliance, and remote site monitoring with periodic regional travel... 
    Senior
    Contract work
    Work at office
    Remote work
    Worldwide

    Worldwide Clinical Trials

    Minnesota
    a month ago
  • $97k - $193k

     ...Senior Clinical Research Associate position with a global CRO supporting psychiatry trials across the Midwest. The role involves managing research activities at clinical trial sites, including study initiation, site training, compliance monitoring, and study closeout,... 
    Senior
    Work at office
    Remote work

    Worldwide Clinical Trials

    Minnesota
    a month ago
  • $97k - $193k

     ...Senior Clinical Research Associate role supporting CNS and rare disease studies across central U.S. sites. Manages site activities from initiation through closeout, including regulatory compliance, data quality, and safety reporting. Remote position with required regional... 
    Senior
    Contract work
    Work at office
    Remote work

    Worldwide Clinical Trials

    Minnesota
    a month ago
  •  ...Parexel FSP is looking for a CRA/Sr CRA in the US. Oncology Experience required. Cell therapy experience is strongly preferred. Job Purpose: The Clinical Research Associate (CRA) has local responsibility for the delivery of the studies at allocated sites and... 
    Senior
    Local area
    Remote work
    Flexible hours
    Shift work

    PAREXEL

    Saint Paul, MN
    4 days ago
  • $97k - $193k

     ...Worldwide Clinical Trials seeks a Senior Clinical Research Associate to manage psychiatric research activities at clinical trial sites across the Central U.S. The role involves site selection, regulatory documentation, staff training, and remote monitoring of studies... 
    Senior
    Work at office
    Remote work
    Worldwide

    Worldwide Clinical Trials

    Minnesota
    a month ago
  • $106k - $133k

     ...salary range at the Consultant level is $106,000 - $133,000, at the Senior Consultant level is $133,000 - $166,000, and at the Principal...  ...or other compensation information in this posting, please contact us at: [1] ****@*****.***. Please note, this recipient is not... 
    Senior
    Temporary work
    Work at office
    Local area

    Slalom

    Minneapolis, MN
    4 days ago
  • $130k - $160k

     ...to join our team in the beautiful Upper Midwest Region of the U.S .Our systems are trusted...  ...systems can be found in quality control, research and development and educational laboratories...  ..., MN, Chicago, IL or Milwaukee, WI. As a Senior Sales Engineer at Instron, you’ll lead... 
    Senior
    Temporary work
    Local area
    Immediate start
    Night shift

    Illinois Tool Works

    Minneapolis, MN
    1 day ago
  • Job SummaryThe Senior Program Manager will play a key part on program teams to support the...  ...This person will support Programs in the Midwest. The role will involve leading assignments...  ...service, collaboration, and innovation. Join us, and you will find a home where you can do... 
    Senior
    Full time
    Temporary work
    Work experience placement
    Work at office
    Local area
    Remote work

    Brown and Caldwell

    Saint Paul, MN
    1 day ago
  • $98k - $115k

     ...make an impact at Henkel. What youll do The Senior Territory Sales Manager will be...  ...expanding market presence throughout the Midwest. Territory coverage includes Michigan, Indiana...  ...uniqueness of all our employees is the power in us. Henkel is an equal opportunity employer.... 
    Senior
    Minimum wage
    Local area
    Flexible hours

    Henkel

    Cannon Falls, MN
    1 day ago
  • $1,662 per week

     ...work for you! A work ethic forged in the Midwest, we are here to stand by your side and...  ...minded, awesome candidates to travel with us. Be bold. Enjoy work again. Let us help....  ...information you need, schedule appointments and research costs, to help you save time and money... 
    Hourly pay
    Weekly pay
    Full time
    Contract work
    Work experience placement
    Shift work

    OneStaff Medical

    Winona, MN
    1 day ago
  • $125k - $130k

     ...income benefits, life and AD&D insurance, a 401(k) plan and match, paid time off, and fitness reimbursements. Fair Chance Statement US & Canada We are committed to providing equal employment opportunities in compliance with all applicable Federal, Provincial/... 
    Senior
    Full time
    Local area

    Everbridge

    Minnesota
    20 days ago
  • Experienced Clinical Research Associate - Sponsor Dedicated Syneos Health is a leading fully integrated biopharmaceutical solutions organization built...  ...only make Syneos Health easier to work with, but to make us easier to work for. Whether you join us in a Functional... 
    Contract work
    Interim role
    Local area
    Immediate start
    Remote work
    Flexible hours

    Syneos Health/ inVentiv Health Commercial LLC

    Virginia, MN
    5 days ago
  • $170k - $213k

     ...Chicago, IL, United States; Minneapolis, MN, United StatesWorkplace: RemoteSchedule: Full timePosted: 2026-08-27As a Senior Manager - Energy Solutions (Midwest) here at Honeywell, you will lead and oversee the successful execution of energy-related customer programs. You... 
    Senior
    Temporary work
    Flexible hours

    Honeywell

    Minneapolis, MN
    4 days ago
  • $82k - $105k

     ...solutions, and OneSource services. Job Title Senior Materials Characterization Support Specialist (REMOTE US or CAN) Location(s) US Remote - AL, US...  ...including proficiency in all software platforms of associated supported equipment. Ability to apply sound judgment... 
    Senior
    Full time
    Work at office
    Remote work
    Work from home
    Home office

    PerkinElmer

    Minnesota
    16 days ago
  • $97k - $193k

     ...Worldwide Clinical Trials seeks a Senior Clinical Research Associate to manage oncology study activities across Central U.S. sites. This role involves site selection, regulatory oversight, training, compliance monitoring, and occasional travel for study initiation visits... 
    Senior
    Contract work
    Work at office
    Worldwide

    Worldwide Clinical Trials

    Minnesota
    a month ago
  • $228k - $342k

     ...invasive surgery worldwide.The Senior Director, Downstream Marketing...  ..., translating customer, clinical, competitive, and business insights...  ...worldwide customer and market research, competitive analysis, segmentation...  ...of Medtronic, please contact us immediately at ****@*****.***... 
    Senior
    Full time
    H1b
    Work at office
    Local area
    Immediate start
    Worldwide
    Flexible hours

    Medtronic

    Saint Paul, MN
    1 day ago
  • $143.83k - $155.63k

     ...Demonstrated analytical/critical thinking skills, attention to detail, and research skills.• Demonstrated negotiation skills for contracts or...  .../ Protected VeteransJob SummaryID: 2026-75671Job Location: US-VA-Chantilly | US-MN-Bloomington | US-AZ-Scottsdale | US-VA-ManassasRequired... 
    Senior
    Contract work
    For subcontractor
    Flexible hours

    General Dynamics Mission Systems

    Minneapolis, MN
    2 days ago
  •  ...Clinical Technician OpportunityAre you passionate about healthcare and seeking an exciting...  ...knowledge within the healthcare industry. Join us today and let your passion for healthcare...  ...experience working within specialty care.Midwest ENT CultureHere at Midwest ENT, we are... 
    Full time
    Relocation
    Monday to Friday

    Midwest Ear Nose & Throat Specialists

    Saint Paul, MN
    5 days ago
  • $159.75k - $225.5k

     ...capture moments that reflect who they uniquely are.We are seeking a Senior Principal Software Engineer to lead the design and development of...  ...which Shutterfly is registered to do business. This includes all US states except District of Columbia, North Dakota, Mississippi,... 
    Senior
    Remote work

    Shutterfly

    Eden Prairie, MN
    12 hours ago
  • $200.7k - $211.68k

     ...RF, undersea, interstellar space and everything in between.As a Senior Deputy PM Engineer, you’ll plan, authorize and monitor engineering...  ...Disabilities / Protected VeteransJob SummaryID: 2026-74907Job Location: US-MN-BloomingtonRequired Clearance: Secret, obtainable within... 
    Senior
    Casual work
    Remote work
    Work from home
    Flexible hours

    General Dynamics Mission Systems

    Bloomington, MN
    4 days ago
  • $169.1k - $198.8k

     ...Manager to join the Technology and Experience practice in one of our US offices.This role focuses on leveraging artificial intelligence...  ...into modern software delivery.ResponsibilitiesPartner with senior stakeholders to define product strategies that incorporate AI-driven... 
    Local area
    Immediate start
    Flexible hours

    West Monroe Partners

    Minneapolis, MN
    1 day ago
  •  ...your future with United Rentals! The Senior Construction Manager is responsible for complex...  ...will be located in the Mid-Central/Midwest** What you’ll do: Strategic Project...  ...Rentals’ policies and procedures. Why join us? We don’t just “talk the talk!” We’re... 
    Senior
    Hourly pay
    Contract work
    For contractors
    Night shift

    United Rentals

    Little Canada, MN
    a month ago
  •  ...Job Description Job Description Senior Cultural Resources Specialist – Principal Investigator Location: Minneapolis, MN Travel...  ..., and construction monitoring projects across the Upper Midwest. This role is responsible for overseeing cultural resources... 
    Senior
    Work at office

    MSR Technology Group

    Minneapolis, MN
    more than 2 months ago
  • $193k - $236k

     ...scale global transformation programs, mentor senior consultants and architects, and...  ...Microsoft Fabric, BigQuery, Redshift, and associated cloud ecosystems* Experience designing AI...  ...information in this posting, please contact us at: [1] ****@*****.***. Please note... 
    Temporary work
    Work at office
    Local area

    Slalom

    Minneapolis, MN
    2 days ago
  • $82.97k - $133k

     ...meaningful business value? Whether you bring deep expertise as a senior leader or strategic enterprise-level experience as a principal-level...  ...for any part of the application and hiring process may contact us at ****@*****.***$82,970-$133,000Job... 
    Senior
    Ongoing contract
    Contract work
    Work at office

    Marvin

    Warroad, MN
    4 days ago
  • $130k - $140k

     ...accommodation or an alternative application process. Senior Client Executive Full Time Sales Minneapolis Medina, MN, US Salary Range: $130,000.00 To $140,000.00...  ...of enterprise relationships in Minnesota and the Midwest. Experience managing complex, multi-stakeholder... 
    Senior
    Full time
    Work at office

    Keyva

    Saint Paul, MN
    1 day ago
  • $170k - $230k

     ...intellectual curiosity, and the ability to simplify complexity for senior audiences.Diverse ExperiencesAWS values diverse experiences. Even...  ...inclusion and empower our people to take pride in what makes us unique. Our inclusion events foster stronger, more collaborative... 
    Flexible hours
    Day shift

    AmazonWebServices

    Minneapolis, MN
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Clinical Research Associate - CNS (US, Midwest). Be the first to apply!