Senior Finance Manager

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world‑class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe. Our Frederick Manufacturing Center (FMC) is one of 30 production facilities in 18 countries that creates life‑changing medicines for people around the world. The Frederick manufacturing facility is a biologics manufacturing site that makes a direct contribution to treating people with cancer, respiratory and autoimmune conditions across the globe. It’s challenging but highly rewarding work, involves more than 700 talented people throughout the manufacturing lifecycle and supporting office functions. We work hard to deliver life‑changing medicines to patients, and we take time to have fun and celebrate our accomplishments. From catered site festivities to competitive events, community outreach activities, environmental and wellness showcases and team‑building events, we take time to recognize our achievements. We are dedicated to creating a culture of inclusion and collaboration. We are committed to continuous learning and offer ongoing skill building and training for our staff and encourage additional secondary schooling with tuition reimbursement of 100% up to $10,000 each year. The FMC is also an award‑winning employer and has been recognized as a ‘Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’ distinction in 2015 and 2019. Come join our award‑winning team and support the manufacturing of life‑changing medicines for patients across the world. Everything we do is to make people’s lives better. To us it’s personal, as we invent, make, deliver and support. Taking our cutting‑edge innovations from our science labs to patients. Fueled by our aspiration to deliver accelerated growth for our company and to make people’s lives better, there’s never been a more exciting time to shape the next phase of Operations’ evolution and growth. We explore, willing to support new ideas, go above and beyond to find better solutions, every day. This is a place for the resilient – hungry for new challenges and diverse opportunities. The driven – willing to learn, take personal accountability and step out of their comfort zone. To build a collective legacy of doing good for people, the environment and society. Why Join Operations? Here we turn molecules to medicines, bringing our Research & Development pipeline to life through a rigorous process of development, manufacturing, testing and delivery. In our fast‑paced, growing environment, embrace an exciting opportunity to build a long‑term, varied career. With a huge variety of global opportunities and learning from other teams this is the place to embrace lifelong learning and build capabilities, setting your own direction and pace. If you have the passion and the drive to accelerate growth and make people’s lives better – then this is the place for you. As a Senior Finance Manager in Frederick, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. It offers one of the most exciting, fast paced, challenging, and rewarding work environments in the world of operations, supply chain and manufacturing. Responsibilities Reviews monthly financial results and variance analysis for the site manufacturing income statement in coordination with our center of excellence team Coordination in the compilation of a comprehensive monthly financial package Able to provide analysis on calculating accruals/reserves Provides guidance, insight and technical insight into the multi‑year budgeting process Able to provide guidance, support and then effectively communicate to multiple parties the impact the cost changes in our annual product cost setting process Forecasting coordination with site leadership while making recommendations to support effective teams Compliance – assists in the development and review of internal controls on a monthly basis for financial compliance and testing by internal and external parties. Independently and timely performs non‑recurring, one‐off projects and other analysis as delegated by the site controller. Analysis of complex income statement transactions and balance sheet entries and reconciliations Reviews financial results monthly and provides variance analysis. Partners with an off‑site accounting group to effectively manage month‑end processes and multi‑year budgeting scenarios. Works collectively with team to identify new processes and system improvement opportunities while working to resolve or escalates repetitive and/or complex discrepancies. Independently functions to analyze gaps / issues related to manufacturing variances. Partner with the site management to assess problems from multiple angles and develop recommendations. Communicates both basic and advanced financial information to senior leaders including potential impacts and actions. Minimum Requirements Bachelor’s degree in Finance, Business, Accounting, Economics, or any relevant field. 8+ years of relevant experience Preferred Requirements Master or MBA Why AstraZeneca? At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life‑changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio‑pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods, and bringing unexpected teams together. Interested? Come and join our journey. Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you! Next Steps – Apply today! To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a phenomenal fit, please share this posting with them. Find out more on Social Media LinkedIn Facebook Instagram About Operations The annual base pay (or hourly rate of compensation) for this position ranges from $132,827 to $199,240. Hourly and salaried non‑exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at‑will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors Date Posted: 20-Jul-2026 Closing Date: 24-Jul-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. #J-18808-Ljbffr