Global Development Lead, Internal Medicine, Sr. Director (non-MD)

Global Development Lead, Internal Medicine, Sr. Director (non‑MD) The Global Development Lead (GDL) represents Clinical on the Global Medicine Team and is the single clinical point of accountability for clinical development for assigned asset(s) in Internal Medicine. The individual will lead the cross‑functional Clinical Development Team, including clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations colleagues, in the design, execution and interpretation of studies in support of worldwide regulatory submissions. The GDL is accountable for creating and gaining endorsement for the Clinical Development Plan and associated protocol design documents. They may also act as a key partner to external companies in support of Pfizer’s Partner of Choice model and may assume responsibility for other clinical leadership opportunities in support of the Obesity portfolio. Responsibilities Partners effectively with the Medicine Team Lead to negotiate tradeoffs, milestones and ensure delivery of the clinical program in line with agreed timelines and budget. Responsible for comprehensive clinical development plan to secure approval and reimbursement globally (including China and Japan) and for creating the pediatric investigation plan / pediatric study plan and associated protocol design documents working closely with individual trial clinicians to ensure trial feasibility and optimized operational execution. Provides product/program specific input for target product profile(s). Willingness to bring innovative thinking and bold decision making across clinical development programs and individual studies. Develops specific clinical development enabling strategies including digital/innovation and patient engagement approaches. Partners with trial clinicians on governance reviews (incl Sci/Ops) for assigned clinical studies and provides category clinical development strategy input and insights. Provides therapy area/indication expertise in support of clinical review of clinical data – including CRF design, assistance in signal interpretation, contextualizing adverse events as required. Provides specialized medical monitoring support for individual trial team, if required. Key partner in trial‑level statistical analysis plan, table‑listings‑figures, database release in partnership with statistics and programming. Develops submission level deliverables (IAP, IARP and submission TLFs); responsible for submission deliverables including SCE and SCS. Supports appropriate interpretation and communication of clinical trial data. Reviews and approves submission level safety narrative plan. Supports product label development and maintenance. Engages key external stakeholders (e.g., Ad boards, Steering Committees, DMC, adjudication committees, patients and patient advocates) to drive strategic insight generation to support clinical development strategy and PDD development. Provides regulatory submission support (DSUR, PBRER) and product defense. Ensures compliance with internal SOPs and external regulatory standards. Reviews IIR proposals. Qualifications Education PhD/PharmD Experience Background in chronic weight management, endocrinology or internal medicine with experience in Phase 1‑3 clinical development and translational medicine. 8+ years of relevant experience and track record of success in academia and/or the biopharmaceutical industry in clinical research and development. Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, adverse event management. Demonstrated clinical/medical, administrative, and project management capabilities, as well as effective verbal and written communication skills. Demonstrated experience managing and training large teams in clinical development. Demonstrated experience in designing and launching large teams (preferred). Candidate demonstrates a breadth of diverse leadership experiences and capabilities including influencing, collaborating, coaching, and guiding colleagues to achieve meaningful outcomes and create business impact. Competency Requirements Medical / Scientific credibility/excellence – track record of achievement in pharmaceutical development, ability to coordinate and execute clinical development or lifecycle strategy, understanding of complexities and recent developments in principal disease areas, and discussion of scientific and regulatory issues. Management experience – ability to work in a highly complex matrixed environment and influence cross‑functional teams. Leadership – persuasive and effective leader of staff. Influencing – ability to manage and motivate internal teams on clinical trials. Conflict Management – act as mentor/coach, navigate conflicts, maintain professional equity. Team Building – fosters open dialogue, shares wins, builds morale, creates belonging. Accountability – personal responsibility for results, pushing self and others to exceed goals. Change agility – ability to demonstrate perspective and poise in uncertainty and get things done amid organizational change. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including influencing, collaborating, coaching, and guiding colleagues. Compensation & Benefits The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, the position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in the share‑based long‑term incentive program. Benefits offered include a 401(k) plan with Pfizer matching contributions and an additional Pfizer retirement savings contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Work Location & Travel Up to 30% travel may be required. Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week. Relocation Assistance Relocation assistance may be available based on business needs and/or eligibility. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States. U.S. work visa sponsorship (such as TN, O‑1, H‑1B, etc.) is not available for this role now or in the future. #J-18808-Ljbffr