Senior Operations Manager

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Sr. Operations Manager

Schedule: Monday – Friday, 6:00 AM – 4:00 PM (flexibility required)
Location: Tolleson, AZ
Travel: <5%

The Sr. Operations Manager (M3) leads multiple operations teams within a high-volume distribution center, driving execution, performance, and continuous improvement across core functions. This role sets operational strategy, establishes performance standards, and ensures alignment to business objectives, while delivering safe, compliant, and cost-effective operations.

Operating at a senior leadership level, this role leads through supervisors and frontline leaders, influencing outcomes through people, process, and data. The Sr. Manager is accountable for operational excellence, talent development, and building a high-performance culture that supports long-term business growth.

Operational Leadership & Strategy

• Set direction and priorities for Operations Supervisors and support teams, aligning execution to DC and enterprise goals
• Establish and monitor KPIs (service, quality, cost, safety) and drive accountability to performance targets
• Lead cross-functional planning to optimize throughput, service levels, and operational efficiency

People Leadership & Culture

• Lead through managers and supervisors, ensuring strong engagement, development, and succession planning
• Build and sustain a high-performance, inclusive culture grounded in I2CARE and ILEAD behaviors
• Coach leaders to drive accountability, performance management, and team development

Execution & Continuous Improvement

• Identify root causes of operational challenges and implement sustainable process improvements
• Drive change management initiatives to improve productivity, reduce cost, and enhance service outcomes
• Standardize processes and ensure consistent execution of SOPs across functions

Safety, Compliance & Quality

• Ensure compliance with all company, federal, state, and local regulations
• Champion a safety-first culture and enforce quality standards across operations
• Maintain audit readiness and operational controls across inventory and distribution processes

Financial & Operational Oversight

• Manage budgets, labor planning, and expense control to meet financial targets
• Leverage data and analytics to inform decisions and improve operational performance
• Partner with site and enterprise leaders to align operational plans with business strategy

Minimum Qualifications

• 7+ years of operations experience (distribution, warehouse, manufacturing, or production)
• 7+ years of people leadership experience, including leading through supervisors or managers
• 5+ years of experience leading change management or continuous improvement initiatives
• Experience managing budgets, expenses, and operational performance metrics
• Advanced analytical skills with the ability to interpret data and drive insights
• Strong communication skills with ability to influence senior leadership
• Proficiency with Microsoft Office; experience with WMS systems

Preferred Qualifications

• Bachelor’s degree
• Six Sigma or Lean experience
• Knowledge of FDA and OSHA regulations
• Experience with JDE or similar ERP systems

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$85,500 - $142,500

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com .

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) View email address on click.appcast.io or (Canada) View email address on click.appcast.io . Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!