Principal Scientist (Director), Translational Medicine - Infectious Diseases
$260.3k - $409.7kMerck
Merck seeks a physician-scientist to lead translational medicine and early clinical development for infectious disease therapeutics. The role bridges discovery research and clinical trials, requiring expertise in target validation, biomarker strategy, and clinical pharmacology across development phases.
Responsibilities
- Partner with discovery teams to identify and validate novel infectious disease targets using clinical data
- Lead early clinical development strategy from preclinical stage through Phase 2 proof-of-concept studies
- Design and execute clinical pharmacology studies across all development phases including drug-drug interactions
- Develop biomarker validation strategies through experimental medicine and cross-functional collaboration
- Provide regulatory and scientific support for clinical trial design and filing preparation
Requirements
- MD or MD/PhD degree
- Strong background in clinical translational research
- Expertise in infectious disease and anti-infective development
- Experience leading early-phase clinical development programs
- Knowledge of clinical pharmacology and biomarker strategy
Vacancy posted 10 days ago
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