Sr. Director, Pricing Transformation and AI Enablement

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care. What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you. Job Title: Sr. Director, Pricing Transformation and AI Enablement Position Summary The Sr. Director, Pricing Transformation and AI Enablement leads the strategic modeling and enterprise transformation of pricing across McKesson, leveraging advanced analytics, data, and AI capabilities. This role partners closely with the Chief Data and AI Officer to translate complex commercial and operational pricing challenges into measurable, data-driven decisions that drive margin and business performance. Serving as a senior bridge between Pricing, Sourcing, Distribution, and technical AI/data teams—as well as governance partners including Legal, Privacy, and Cybersecurity—this role ensures pricing initiatives are commercially impactful, compliant, and aligned with enterprise priorities. This role operates initially as an individual contributor, delivering results through matrixed data science, engineering, and analytics teams, with the expectation to evolve into a leadership role building enterprise pricing analytics capabilities as McKesson’s AI transformation matures. Key Responsibilities Pricing Strategy and Modeling Partner with Pricing, Sourcing, and Finance leadership to prioritize and scope high-value pricing opportunities, including large deals, discount optimization, and revenue management at scale Lead the design of AI- and analytics-driven pricing models across the full margin lifecycle (acquisition cost, resale pricing, and distribution economics) Identify opportunities where advanced modeling and data insights can drive incremental margin performance Define, track, and communicate financial outcomes of pricing initiatives, ensuring clear and attributable ROI AI Enablement and Use Case Development Identify and prioritize AI and GenAI use cases across the pricing value chain Translate business challenges into well-defined analytical opportunities, balancing competing objectives and securing stakeholder alignment Serve as a senior cross-functional liaison to ensure pricing initiatives meet compliance and ethical standards in partnership with Legal, Privacy, and Cybersecurity Advise business leaders on value, feasibility, and risk trade-offs to enable adoption of data- and AI-driven pricing strategies Enterprise Influence and Alignment Drive alignment across business, technical, and governance stakeholders to enable scalable pricing transformation Influence senior leaders and stakeholders to adopt new data-driven decision frameworks Deliver through matrixed teams without direct authority, ensuring execution across multiple functions Minimum Requirements (Knowledge, Skills, & Abilities) 15+ years of experience translating complex commercial problems—particularly in pricing and revenue management, into analytics or AI-driven solutions at enterprise scale Prior experience in pricing within a large, complex enterprise environment Advanced degree in a quantitative field (e.g., Operations Research, Statistics, Economics, Applied Mathematics) Deep expertise in quantitative modeling techniques, including machine learning (classification, regression, clustering, neural networks), optimization, and simulation Demonstrated ability to lead and deliver results through influence in a highly matrixed environment Strong track record of tying business initiatives to measurable financial outcomes, including incremental margin and quantified ROI Ability to translate complex analytical findings into clear, actionable insights for both technical and executive audiences Experience shaping AI strategy and governance, with ability to operate as a trusted advisor to senior leadership Preferred Qualifications Experience with enterprise-scale data and AI platforms (e.g., Databricks, Snowflake) Working knowledge of Python or SQL to effectively engage with technical teams Experience in pharmaceutical distribution, healthcare, or other regulated, high-volume industries Exposure to GenAI or agentic AI use case development Travel requirement: 10-20% Physical Requirements: General Office Demands Relocation assistance / allowance is not budgeted for this position We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here. Our Base Pay Range for this position $219,200 - $365,300 McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind: McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application. McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates. McKesson job postings are posted on our career site: careers.mckesson.com. McKesson is an Equal Opportunity Employer McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page. McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) View email address on click.appcast.io or (Canada) View email address on click.appcast.io. Resumes or CVs submitted to this email box will not be accepted. Join us at McKesson! McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care. What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.