Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Investigator

Metric Bio

Job Description

Principal Investigator – Psychiatry Clinical Research

Los Angeles, California

Metric Bio is partnered with a leading clinical research site network to appoint an experienced Principal Investigator with a strong background in Psychiatry studies.

This is an exciting opportunity to join a high-performing research organisation at the forefront of CNS and psychiatric clinical trials, supporting cutting-edge therapies across a diverse patient population in the Los Angeles area.

The Opportunity

As Principal Investigator, you will provide medical oversight across a broad portfolio of Psychiatry clinical studies, working alongside an established research infrastructure with dedicated coordinators, raters, and operational support teams.

The organisation has built a strong reputation for delivering complex CNS trials and offers access to a robust patient database, advanced research capabilities, and long-term study pipelines with global sponsors.

Key Responsibilities

  • Serve as Principal Investigator across Phase I–IV Psychiatry clinical trials
  • Ensure patient safety, protocol compliance, and regulatory oversight
  • Conduct psychiatric evaluations and study assessments
  • Collaborate closely with sponsors, CROs, and internal research teams
  • Support patient recruitment and retention strategies
  • Maintain high-quality standards in line with GCP and FDA regulations
  • Provide leadership and mentorship within the clinical research team

Requirements

  • MD or DO
  • Active and unrestricted California medical license
  • Prior experience as a Principal Investigator or Sub-Investigator in clinical research
  • Strong understanding of CNS/Psychiatry trials
  • Experience working within industry-sponsored studies preferred
  • Passion for advancing innovative mental health treatments through research

Why Join?

  • Join one of the most respected and rapidly growing research site networks in the industry
  • Strong pipeline of Psychiatry and CNS studies
  • Dedicated operational and recruitment support
  • Competitive compensation package
  • Opportunity to contribute to breakthrough mental health therapies
  • Collaborative, patient-centric research environment

For a confidential discussion, please apply directly or contact - Oli Oldham - View email address on ziprecruiter.com for further information.

Vacancy posted 8 days ago
Similar jobs that could be interesting for youBased on the Principal Investigator in San Jose, CA vacancy
  •  ...Cerebras is adding an ML team that can focus on a new ML effort that can align with existing teams. We are seeking a principal investigator who will partner with our ML leaders to formulate the new effort and to build up the new team and capabilities. This new team... 
    Principal

    CEREBRAS SYSTEMS INC.

    Sunnyvale, CA
    1 day ago
  • $162.7k - $263.18k

    Palo Alto Networks, Inc. is looking for a Principal Security Researcher in Santa Clara, California. The ideal candidate should hold a BS/MS/PhD in Computer Science or Computer Engineering and have 6 to 8+ years of experience. Responsibilities include developing new features... 
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    12 hours ago
  • $205.5k - $310.2k

    Dell Technologies is seeking a Senior Principal Security Software Engineer to contribute to the design and architecture of cryptography security software. This role involves implementing encryption algorithms and collaborating with top engineers. Candidates should have... 
    Principal

    Dell Technologies

    Santa Clara, CA
    12 hours ago
  • $180k

     ...at the forefront of protecting Uber. We are a hands-on, fast-paced team that responds to security incidents, conducts forensic investigations, and builds automated solutions to scale our defenses. As a Senior Security Investigator , your role is to lead complex, high-... 
    Suggested

    Uber

    Sunnyvale, CA
    12 hours ago
  • $162.7k - $263.18k

    Job Summary The DNS Security Research team delivers high-quality content to our products to prevent successful cyberattacks, focusing especially on DNS security, IP layer defense, and network security. We design, build, and maintain various detection systems and data infrastructures...
    Principal

    Palo Alto Networks

    Santa Clara, CA
    12 hours ago
  • Intel Corporation in Santa Clara is looking for a Senior Principal Engineer specializing in Physical Design. This role involves driving physical design implementation for custom IP and SoC designs. The ideal candidate will have extensive experience in synthesis, static... 
    Principal

    Intel Corporation

    Santa Clara, CA
    12 hours ago
  • $162.7k - $263.18k

    Key Responsibilities Develop and maintain a comprehensive, industry-leading repository of vulnerability content to enhance detection and mitigation strategies. Shape and drive the tactical response to zero-day and critical vulnerabilities across all attack surfaces, ensuring...
    Principal
    Work at office
    Visa sponsorship
    Work visa

    Palo Alto Networks

    Santa Clara, CA
    1 day ago
  • $162.7k - $263.18k

     ...supports real‑time problem‑solving, stronger relationships, and the kind of precision that drives great outcomes. Your Career As a Principal Security Researcher (Antivirus Systems), we are looking for a motivated, intelligent, hardworking and creative individual to join... 
    Principal
    Full time
    Work at office

    Palo Alto Networks, Inc.

    Santa Clara, CA
    4 days ago
  •  ...in the country for research commercialization success. As our Principal Distributed Systems Research Engineer, you won't just be...  ...contracts to push our technology forward. Serve as Principal Investigator and/or staff member on externally‑funded research projects. Actively... 
    Principal
    Work from home
    Home office
    Flexible hours

    Real-Time Innovations

    Sunnyvale, CA
    4 days ago
  • $147k - $237.5k

    Palo Alto Networks, Inc. is seeking a Senior Principal Software Engineer in Santa Clara, CA. This role requires leading the design and development of next-generation Layer 7 security capabilities. Candidates should have extensive experience in software engineering, particularly... 
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    1 day ago
  • $114k - $213.4k

    A leading defense technology employer is seeking a Principal or Senior Principal Technical Services Project Manager in Sunnyvale, CA. This role involves managing project operations, fostering teamwork, and ensuring adherence to safety practices in a manufacturing environment... 
    Principal

    Northrop Grumman Corp. (AU)

    Sunnyvale, CA
    3 days ago
  • $170k - $277k

    Palo Alto Networks, Inc. is seeking a Senior Principal Software Engineer in Santa Clara, California to lead the design and development of advanced Layer 7 security capabilities for next-generation firewall platforms. This role requires expert-level proficiency in C, strong... 
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    3 days ago
  • $170k - $277k

    Palo Alto Networks, Inc. is looking for innovative engineers to design and develop security features for next-generation firewalls. You will work closely with cross-functional teams, applying your programming skills to tackle real-world security problems. A successful candidate...
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    4 days ago
  • $129.3k - $193.9k

    Northrop Grumman Corp. (JP) is seeking a Deputy Operations Program Manager in Sunnyvale, CA. This role involves leading project teams, managing manufacturing operations, and ensuring program delivery meets schedule and budget. Ideal candidates bring extensive experience...
    Principal

    Northrop Grumman Corp. (JP)

    Sunnyvale, CA
    3 days ago
  • $126k - $204.5k

    Palo Alto Networks, Inc. is looking for a candidate to engage in security research, focusing on vulnerabilities and AI applications for threat detection. Responsibilities include designing security tools, analyzing network traffic, and collaborating with teams. A degree...
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    4 days ago
  • $219k - $305k

    Google Inc. is seeking a Senior Principal Analyst in Sunnyvale, CA, to lead safety strategies for generative AI launches, ensuring business objectives. This role requires collaboration with Engineering, Product, and Policy teams to promote user safety across products like... 
    Principal

    Google Inc.

    Sunnyvale, CA
    4 days ago
  • Ll Oefentherapie in Santa Clara is seeking a visionary technical leader for Oracle Cloud Infrastructure (OCI). You will provide technical leadership and mentorship while delivering high-performance cloud services and platforms. Ideal candidates will have extensive experience...
    Principal

    Ll Oefentherapie

    Santa Clara, CA
    4 days ago
  • $147k - $237.5k

    Palo Alto Networks, Inc. is looking for a Principal Software Engineer to lead the technical development of innovative cloud security solutions. You will collaborate with cross-functional teams to design and implement scalable cloud architectures. Candidates should possess... 
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    1 day ago
  • $118.5k - $244.1k

    Apple Inc. is seeking a Software Integrity Engineer for its Cocoa QA team in Cupertino, California. This role involves triaging bug reports, developing automation tools, and collaborating with engineering teams to maintain high-quality standards across macOS, iOS, watchOS...

    Apple Inc.

    Cupertino, CA
    4 days ago
  • $152k - $208.5k

    Applied Materials, Inc. is looking for an Insider Risk Investigator in Santa Clara, CA. This full-time position requires leading insider risk investigations and cross-functional collaboration to protect our intellectual property and data. The ideal candidate should have... 
    Full time

    Applied Materials, Inc.

    Santa Clara, CA
    1 day ago
  • $152k - $208.5k

     ...wherever you may go. Learn more about our benefits.**Position Description**Applied Materials is seeking an experienced Insider Risk Investigator to join our Insider Risk Team. This role sits within a highly collaborative, multidisciplinary team within our Legal and... 
    Full time
    Relocation

    Applied Materials, Inc.

    Santa Clara, CA
    1 day ago
  • A leading aerospace firm is seeking a Sr. Principal Program Project Management Specialist in Sunnyvale, CA. This role involves managing program schedules, assisting in risk management, and coordinating with stakeholders on project tasks. Ideal candidates should have a Bachelor... 
    Principal
    Work at office

    Northrop Grumman

    Sunnyvale, CA
    3 days ago
  • Palo Alto Networks, Inc. is looking for a Sr Principal Software Engineer to lead the development of next-generation cloud security solutions in Santa Clara, California. This role involves driving technical leadership and collaborating with cross-functional teams to implement... 
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    1 day ago
  • $113.5k - $170.3k

    Northrop Grumman (Corporate) seeks a Senior Principal Program Cost Control Analyst in Sunnyvale, CA. The role involves providing financial support by preparing budgets, analyzing costs, and monitoring contracts. Candidates require a Bachelor's degree in Finance or related... 
    Principal

    Northrop Grumman (Corporate)

    Sunnyvale, CA
    4 days ago
  • $210k - $255k

    Astera Labs (NASDAQ: ALAB) provides rack-scale AI infrastructure through purpose-built connectivity solutions. By collaborating with hyperscalers and ecosystem partners, Astera Labs enables organizations to unlock the full potential of modern AI. Astera Labs' Intelligent...
    Principal
    Worldwide
    Flexible hours

    Astera Labs

    San Jose, CA
    3 days ago
  • $170k - $277k

    Palo Alto Networks, Inc. is looking for a skilled developer to join their Layer-7 Security group in Santa Clara, CA. The role involves designing and developing device identity solutions for Next-Generation Firewalls, with an emphasis on functionality and performance. Candidates...
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    12 hours ago
  • $170k - $277k

    Palo Alto Networks, Inc. is seeking a Senior Principal Software Engineer to lead the technical vision for the Cortex Xpanse ASM platform. This role involves architecting scalable backend systems and data pipelines while mentoring engineering talent. The ideal candidate... 
    Principal

    Palo Alto Networks, Inc.

    Santa Clara, CA
    4 days ago
  •  ...A cybersecurity company is seeking a Principal Consultant for SOC Transformation & XSIAM Deployment. This remote role requires a seasoned leader with over 10 years of experience in SIEM deployment and security operations. You will lead large-scale SOC transformations,... 
    Principal
    Remote work

    Palo Alto Networks

    Santa Clara, CA
    1 day ago
  • $205.5k - $310.2k

    Senior Principal Security Software Engineer - C and Cryptographic Systems Join us to do the best work of your career and make a profound social impact as a Senior Principal Data Security Software Engineer on our Software Engineering Team. This is an on‑site position in... 
    Principal
    Relocation

    Dell Technologies

    Santa Clara, CA
    1 day ago
  • Proofpoint is seeking a Principal ML Architect to lead the design and development of next-generation AI systems focused on cybersecurity. In this role, you will leverage advanced machine learning techniques, including LLMs and SLMs, to create intelligent security solutions... 
    Principal

    Proofpoint

    Sunnyvale, CA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Investigator. Be the first to apply!