Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Machine Learning Engineer

Harnham

By joining our clients team as a Senior Machine Learning Engineer , you will play a pivotal role in building cutting-edge AI products that directly impact how new therapies reach patients. We’re looking for an experienced ML engineer who is passionate about turning advanced AI research into scalable, real-world solutions. You thrive on solving complex problems, pay close attention to detail, and consistently seek to automate and improve processes. You shine as a collaborator and excel as an individual contributor, with the courage to tackle challenging problems and the humility to learn and adapt. Your initiative and discipline allow you to thrive while working remotely, and your high degree of empathy and communication skills makes you the kind of colleague everyone wants on their team.

What You’ll Be Working On:

  • Build and deploy AI-driven products that accelerate clinical trials and improve patient outcomes. Your work will deliver scalable machine learning solutions to complex, real-world problems in clinical research.
  • Develop advanced ML models and LLM-powered agents for critical use cases like patient recruitment, enrollment forecasting, and study feasibility. You’ll also help expand our AI knowledge base architecture to support these innovative solutions.
  • Leverage modern cloud tools and MLOps best practices to build robust data pipelines and deploy models at scale. You’ll use technologies like Python (and Clojure), AWS services (Athena, Bedrock, SageMaker, etc.), dbt, Prefect, and CI/CD automation with monitoring to ensure models are reliable and up-to-date.
  • Collaborate across teams of data scientists, product managers, designers, engineers, and domain experts to integrate AI capabilities into our platform (including Care Access products). Ensure these AI solutions seamlessly support and enhance clinical research workflows for end-users.
  • Continuously learn and innovate. Stay up-to-date with the latest developments in ML/AI (LLMs, NLP, probabilistic modeling, etc.) and proactively bring new ideas to the team. You’ll have the freedom to experiment with cutting-edge techniques and turn promising prototypes into production features that drive our mission forward.

What You’ll Bring:

  • MUST HAVE EXPERIENCE IN HEALTHCARE - Candidates should understand: regulated environments, compliance requirements, security considerations, model governance, bias and fairness concerns
  • Minimum of 5+ years of hands-on experience building and deploying machine learning solutions in production at scale. Proven ability to implement end-to-end ML pipelines from data ingestion to model serving for real-world applications used by real people.
  • Strong programming and data skills: Proficiency in Python and its ML ecosystem (pandas, scikit-learn, TensorFlow/PyTorch), with clean and efficient coding practices. Comfortable working with large datasets, writing complex SQL queries, and leveraging modern data processing frameworks. Experience with functional programming (e.g. Clojure) is a plus but not required.
  • Cloud and MLOps expertise: Experience with AWS and containerization tools like Docker. Familiarity with MLOps best practices such as CI/CD pipelines, automated testing, and monitoring model performance/data drift to ensure reliable, scalable deployments.
  • Deep ML/AI knowledge: Strong understanding of machine learning fundamentals (model selection, training, evaluation, feature engineering) and statistical modeling. Familiarity with NLP and large language models is important.
  • Analytical problem-solving: Ability to break down complex problems and devise effective, efficient ML solutions. You balance pragmatic engineering with scientific rigor, ensuring models are not only accurate but also performant and maintainable in production.

The team wants candidates who can take machine learning products from:

Concept --> Development --> Deployment --> Monitoring --> Scaling

Vacancy posted 22 hours ago
Similar jobs that could be interesting for youBased on the Senior Machine Learning Engineer in Sioux Falls, SD vacancy
  • $100k - $150k

     ...Machine Learning Engineer II, Computer Vision Houston, TX | Remote | Hybrid · Full-time · $100,000 – $150,000 Imagine a warehouse team,...  ...work closely with data, platform, and product teams, and have senior engineers in your corner as you grow. Along the way, you'll... 
    Suggested
    Full time
    Immediate start
    Remote work
    Shift work

    Amniscient

    Sioux Falls, SD
    4 days ago
  • Northrop Grumman Corp. (JP) is seeking a Sr Principal Systems Administrator at Ellsworth AFB, SD, to join a high‑demand IT team supporting flight operations. The role requires directing real-time, multi-user ground systems, ensuring STIG compliance, and performing field...
    Senior

    Northrop Grumman

    Sioux Falls, SD
    19 hours ago
  •  ...building community through regular in-person events. Learn more about our flexible approach to where we work. About the Role: As a Machine Learning Engineer, you will have the opportunity to collaborate closely with senior engineers and product leaders as part of your... 
    Suggested
    Permanent employment
    Full time
    Work at office
    Remote work
    Work from home
    Flexible hours

    Instacart

    Sioux Falls, SD
    4 days ago
  • $107.66k - $161.7k

     ...topics and providing a unique platform to learn and connect with others. Poe : a...  ...About the Team and Role: Our small engineering team works on challenging problems every...  ...product and our company. At Poe, we use Machine Learning in various parts of the product... 
    Suggested
    Remote job
    Full time
    Work experience placement
    Internship

    Quora

    Sioux Falls, SD
    4 days ago
  • $119k - $145k

     ...Position: Senior Data Engineer, Databricks Compensation: $119-$145k, depending on experience Location: Remote Inceed has partnered...  ...check and drug test If you are interested in learning more about the  Senior Data Engineer Databricks opportunity,... 
    Senior
    Remote work

    Jobrapido

    Sioux Falls, SD
    1 day ago
  •  ...OneUS Technologies has partnered with a premier, globally recognized management and technology consultancy to identify talented Senior Data Engineers. Our client specializes in delivering complex, sector-focused strategy and transformation programs for the financial... 
    Senior
    Permanent employment
    Full time
    Remote work
    Monday to Thursday
    Afternoon shift

    OneUS Technologies LLC

    Sioux Falls, SD
    4 days ago
  • $145k - $220k

     ...definitions, and system integration efforts. Evaluate emerging technologies and guide technology roadmaps. Collaborate with global engineering teams, customers, and strategic technology partners. REQUIREMENTS and SKILLS: ~ MS or PhD in Electrical Engineering,... 
    Senior
    Work experience placement
    Work from home
    Worldwide

    Jobrapido

    Sioux Falls, SD
    2 days ago
  • $136.5k - $276.5k

     ...to stretch and grow your career our culture will embrace you. Open up opportunities with HPE. Job Description Senior Technical Marketing Engineer (TME) – Data Center Networking (Apstra) Location: anywhere in the U.S. (remote) HPE is seeking a Technical Marketing... 
    Senior
    Work experience placement
    Remote work
    Work from home

    Hewlett Packard Enterprise

    Sioux Falls, SD
    4 days ago
  •  ...A leading architecture firm in Sioux Falls seeks a Senior Architect to serve as the design authority and provide leadership on multiple projects. This role requires a licensed architect with 8-15+ years of experience. Responsibilities include leading projects, mentoring... 
    Senior
    Relocation package
    Flexible hours

    rsa-create

    Sioux Falls, SD
    19 hours ago
  •  ...applicable. Provide support to market-released products, as necessary. Qualifications: ~ M.S. degree or higher in a Science, Engineering or related technical field of study ~10 – 15 years of experience in a Regulated industry, preferably Medical Devices industry... 
    Senior

    Jobrapido

    Sioux Falls, SD
    1 day ago
  • $26 - $36 per hour

    Good Samaritan Society in Sioux Falls, SD, is seeking a Part Time Days LPN to join our not-for-profit, Christian environment. The role offers 22 hours weekly, a $26–$36 hourly pay range, and a $5,000 sign-on bonus. Schedule includes every other weekend, with two shifts...
    Senior
    Hourly pay
    Part time
    Relocation package
    Shift work
    Day shift

    Good Samaritan Society

    Sioux Falls, SD
    3 days ago
  • $100k

     ...looking for entry-level software programmers Java Full stack developers Python/Java developers Data analysts/ Data Scientists Machine Learning engineers for full time positions with clients. Who Should Apply Recent Computer science/Engineering /Mathematics/Statistics or... 
    Full time
    H1b

    SynergisticIT

    Sioux Falls, SD
    2 days ago
  • Walbridge in the United States seeks an experienced construction leader to provide overall administrative and technical direction for a large, complex project, interfacing with clients, design teams, subcontractors and end users to deliver on scope, schedule and budget...
    Senior
    For subcontractor

    Walbridge

    Sioux Falls, SD
    3 days ago
  • Orca Bio is seeking a Medical Science Liaison to foster relationships with key opinion leaders and support the scientific and clinical strategy for our allogeneic cell therapies. The MSL will collaborate with HCPs in the Great Lakes territory to share trial data, publications...
    Senior

    Orca Bio

    Sioux Falls, SD
    4 days ago
  • Avera Research Institute in Sioux Falls is seeking a Biostatistician to provide essential statistical expertise for health outcomes research. You will design analyses, draft analytic plans and prepare manuscripts, while handling data processing and reporting. The role ...
    Senior

    Avera Health

    Sioux Falls, SD
    3 days ago
  •  ...CVS Health Corporation is seeking an experienced Senior IAM Engineer to enhance and support enterprise IAM platforms, including Ping Identity, LDAP, and authentication solutions. The role covers administration, automation, and 24x7 operational support of SSO, MFA, and... 
    Senior

    CVS Health

    Sioux Falls, SD
    2 hours ago
  •  ...Affirm is seeking a Senior Counsel, Capital Markets to lead and advise on diversified capitalization strategies. The role requires expert knowledge of financing, corporate transactions, and capital markets law, with collaboration across internal teams and external partners... 
    Senior
    Remote work

    Affirm

    Sioux Falls, SD
    3 days ago
  • The Nursing Assistant (NA) serves as caregiver to the resident during the scheduled work period in long term care. Provides resident-centered nursing care and daily living assistance to assigned resident under the supervision of a registered nurse (RN). Knowledge of...
    Senior
    Part time
    Weekend work

    Good Samaritan Society

    Sioux Falls, SD
    19 hours ago
  • CSAA Insurance Group is seeking a Capital Modeling Lead for P&C Insurance to work remotely across the United States. You will lead internal economic capital modeling, build and challenge models, and partner with risk management, actuary, investments, and FP&A to inform...
    Senior
    Remote work

    CSAA Insurance Group

    Sioux Falls, SD
    3 days ago
  •  ...across the Operations organization. You will define readiness for people, processes, and enablement systems, partnering with Product, Engineering, Compliance and vendor teams to drive adoption and measurable outcomes. The role requires 7+ years in program management, strong... 
    Senior
    Remote work

    Affirm

    Sioux Falls, SD
    3 days ago
  •  ...Canistota, SD is hiring for a full-time social services/ counseling role within a not-for-profit setting dedicated to quality care for seniors. You will join an interdisciplinary team to support residents and their families with social, emotional, and practical needs. The... 
    Senior
    Full time

    Good Samaritan

    Sioux Falls, SD
    22 hours ago
  •  ...ISG is a multidisciplinary, employee-owned firm delivering architecture, engineering, environmental, and planning services. The Senior Physical Substation Engineer will lead high-voltage substation physical packages, mentor staff, and serve as a primary client contact... 
    Senior

    I&S Group

    Sioux Falls, SD
    1 day ago
  •  ...Halogen Engineering is seeking a Senior TechSIGINT Systems Engineer to provide enterprise-focused engineering support to the Weapons and Space Modernization Systems Engineering team. The role involves implementing requirements, governing processes, and assessing system... 
    Senior

    Halogen Engineering Group, Inc

    Sioux Falls, SD
    3 days ago
  •  ...Eide Bailly in Sioux Falls, SD is seeking a senior tax professional with a CPA or EA designation and 7+ years of public accounting tax experience, including gift, trust and estate returns. The role emphasizes transfer tax and estate planning expertise. You will review... 
    Senior
    Work at office

    Eide Bailly

    Sioux Falls, SD
    4 days ago
  •  ...KBR is seeking a Senior-Level Ground System Interface Engineer in Sioux Falls, SD, to help advance Earth science data systems. You’ll lead interface design, drive architecture decisions, and collaborate with scientists and mission partners in a fast-paced, mission-driven... 
    Senior

    KBR

    Sioux Falls, SD
    2 days ago
  • $18 - $20.26 per hour

     ...American Baptist Homes of the Midwest is seeking a Certified Medication Aid to provide essential support to residents at Trail Ridge Senior Living. In this role, you will administer medications, assist with daily living activities, and collaborate on care plans, making a... 
    Senior
    Hourly pay
    Afternoon shift

    American Baptist Homes of the Midwest

    Sioux Falls, SD
    19 hours ago
  •  ...TCOM is seeking an Software Engineering Manager to lead software engineers and team leads, shaping architecture and engineering practices across the organization. You will manage staffing, performance, and resource allocation while enabling teams to deliver complex software... 
    Senior

    T-Com

    Sioux Falls, SD
    3 days ago
  •  ...Pathward, N.A. is seeking a Senior Analyst, Quality Control for BSA/AML & Sanctions Operations. The role involves independent quality review of alerts, cases, investigations, merchant acquiring, and sanctions dispositions with read-only access and examiner-ready feedback... 
    Senior
    Remote work

    Pathward, N.A.

    Sioux Falls, SD
    4 days ago
  •  ...Bridges Trust, a privately-owned trust and wealth management firm, seeks a Senior Compliance Analyst in Sioux Falls, SD, reporting to the Chief Compliance Officer. You will conduct compliance monitoring, testing, risk assessments, regulatory reporting, and support examinations... 
    Senior

    Bridges Trust

    Sioux Falls, SD
    19 hours ago
  • Grifols, S.A in Sioux Falls, SD is seeking a Plasma Center Technician to support plasma collection and donor care. You will assist in donor screening, operate plasmapheresis equipment, and help ensure donor safety and product quality. The role requires a high school...
    Senior

    Grifols, S.A

    Sioux Falls, SD
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Machine Learning Engineer. Be the first to apply!