Principal Project Manager

Principal Project Manager Date: Jun 18, 2026 Location: St. Louis, MO, United States, 63146 About Curium Curium is the world's largest nuclear medicine company with more than a century of industry experience. We develop, manufacture and distribute world‑class radiopharmaceutical products to help patients around the globe. Our proven heritage combined with a pioneering approach are the hallmarks to deliver innovation, excellence and unparalleled service. With manufacturing facilities across Europe and the United States, Curium delivers SPECT, PET and therapeutic radiopharmaceutical solutions for life‑threatening diseases to over 14 million patients annually. The name ‘Curium’ honors the legacy of pioneering radioactive researchers Marie and Pierre Curie, after whom the radioactive element curium was named and emphasizes our focus on nuclear medicine. The tagline ‘Life Forward’ represents our commitment to securing a brighter future for all those we serve: an enhanced quality of care for our patients, a trusted partner to our customers, and a supportive employer to our valued team. Summary of Position This Principal Project Manager role provides a unique opportunity to collaborate across the different functions including Regulatory Affairs, Research and Development (R&D), Operations, Quality, Supply Chain, Finance, Legal, HR, Engineering, Marketing and Commercial. This individual will work closely with the Vice President – North American Project Management Office and the Senior Director Project Manager – North American Project Management Office to implement Curium's strategic initiatives and projects. This position requires effective communication on program status to senior leadership across the company. Work Schedule: Monday – Friday 8:00 am – 5:00 pm. Hours could be adjusted. Essential Functions Maintain operational compliance with US and international regulatory agencies and guidelines (e.g., FDA, EU, HC, TGA, PIC/S, ISO, USP, NRC, cGMP, etc.). Coordinate and align multiple shared services activities between board‑approved New Product Development (NPD) and MOB‑related initiatives. Provide Project Management Services for North America Strategic Business Initiative projects that are classified as NPD or MOB. Facilitate key meetings, including core and designated sub‑team meetings. Coordinate MOB and Strategic Business Initiatives to be integrated in escalation and governance processes where critical projects are managed and reported. Support efforts to improve and enhance the PMO process/governance structure and systems initiatives, including resource management across all functional groups for NPD, MOB and other Strategic Business issues; optimize the financial forecasting process; support PMO portfolio software implementations; assist with execution of stage‑gate process for all projects. Provide PM Services, when necessary, to ensure business continuity within the PMO. Present project status, issues and risks to the Project Review Committee team members and provide recommendations on project direction. Work with the PMO group during the concept phase to provide scoping, scheduling and cost information for requirements. Provide PM services/support for elements of Integration activities for M&A. Use Project Management systems to capture and share information from each project to drive continuous improvement and best practices. All other responsibilities as assigned, with or without accommodation. Requirements Bachelor’s level degree in engineering or related sciences or equivalent experience. 8 or more years of experience in the pharmaceutical industry and leading cross‑functional projects. Technical understanding of pharmaceutical processing. Knowledge/experience in aseptic/terminally sterile operations; isolator technology a plus. Knowledge/experience in radiopharmaceutical industry and operations a plus. Experience in manufacturing operations preferred. Team member and team leader experience. Strong evidence and mastery of being a team contributor. Demonstrates strong interpersonal skills, including the ability to maintain composure and professionalism under pressure. Allocate resources effectively across multiple projects and appropriately set priorities. Work well under tight and conflicting deadlines. Excellent written and oral communication skills. Strong interpersonal and negotiation skills, conflict management, priority setting, strategic agility, building effective teams, managing vision and purpose. Strong management, time‑management and organizational skills. PMP certification preferred. Strong computer skills and experience with Microsoft Word, PowerPoint, Excel, Visio, MS Project and other Project Management software; experience in ERP/database management a plus. Lean or Six Sigma trained/certified a plus. Requires travel (10–25 %). Working Conditions Willingness to work in a plant producing radioactive materials and to participate in safety programs designed to minimize potential and/or actual exposure levels. Ability to lift up to 70 pounds, kneel, crouch, twist the upper body, walk, bend, stoop, push, pull, reach and negotiate stairs and evacuation ladders (with or without accommodation); wear and operate safety equipment, enter vessels and inspect equipment. Use of material handling devices (e.g., hand truck, forklift, conveyors) when possible; employ proper lifting and movement techniques to prevent injury. Willingness to wear a variety of personal protective equipment (PPE) and hearing protection as needed. May be required to sit or stand for long periods (8+ hours a day) while performing duties. Good hand‑eye coordination and close attention to detail required. Work indoors and outdoors with exposure to mechanical/moving parts, corrosive, flammable and toxic material, dust, dirt, odors and irritants. Willingness to complete safety training within allotted timeframes and to work in a team‑based environment. Must be able to work outside of regular work hours, including off‑shift, weekend and holiday work as business needs require. Disclaimer The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Equal Opportunity Employer Curium is an equal opportunity employer and believes everyone deserves respect, dignity and equality. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. We believe diversity includes disability and actively encourage applications from people with disabilities. If you require any accommodations during the recruitment process, please let us know—we are happy to support you. #J-18808-Ljbffr