Senior ML Scientist, Biological Systems

Your Impact at LILA Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Science AI (LSAI), we develop autonomous-science capabilities for cellular and tissue biology, spanning single-cell omics, perturbation biology, spatial profiling, imaging, genetics, and multi-modal experimental data that integrate deep biological expertise with foundation modeling and agentic systems. We are seeking a Senior Machine Learning Scientist to help execute this vision by building autonomous life science systems grounded in epistemology, scientific methodology, Bayesian argumentation, and automation. This role will translate the scientific direction of Autonomous Life Science AI into working architectures, workflows, and evaluation methods that allow AI systems to reason rigorously about biological hypotheses, propose experiments, incorporate evidence, and accelerate discovery. This is a hands‑on scientific and technical role for someone who can operate at the intersection of machine learning, biological reasoning, agentic systems, and experimental design. The right person will be comfortable formalizing how scientific knowledge is represented, how uncertainty is handled, how evidence changes belief, and how automated systems can execute increasingly rigorous cycles of life science discovery. What You’ll Be Building Build autonomous life science systems that connect AI reasoning, biological evidence, experimental design, and automated execution. Translate the broader Autonomous Life Science AI vision into concrete architectures, workflows, prototypes, and production-quality research systems. Develop methods for representing hypotheses, uncertainty, evidence, and scientific arguments in ways that enable robust machine reasoning. Apply Bayesian reasoning, epistemology, and scientific methodology to the design of AI systems that can propose, test, and revise biological hypotheses. Design agentic workflows that plan experiments, reason over results, and close the loop between computational predictions and automated laboratory feedback. Partner with ML scientists, experimental scientists, automation teams, and platform teams to ensure systems are biologically grounded and experimentally actionable. Build evaluation frameworks for autonomous discovery systems, including benchmarks for reasoning quality, hypothesis generation, evidence integration, and experimental utility. Contribute to the technical roadmap for autonomous life science research systems and help raise the scientific rigor of the team’s approach. What You’ll Need to Succeed PhD in Computer Science, Machine Learning, Computational Biology, Statistics, Biology, or a related quantitative field. Strong research track record in machine learning, AI for science, computational biology, probabilistic modeling, agentic systems, or a related area. Deep understanding of scientific reasoning, experimental design, uncertainty, and evidence integration. Experience building or researching systems that reason over complex scientific, biological, or experimental data. Strong foundation in modern ML methods, with hands‑on experience in frameworks such as PyTorch, JAX, or TensorFlow. Ability to translate biological questions into computational and ML problems, and to translate ML system behavior back into scientific terms. Strong technical judgment, with the ability to operate in open‑ended research settings where the right architecture, abstraction, or evaluation method is not yet obvious. Excellent collaboration skills across AI, biology, automation, and platform teams. Bonus Points For Experience with Bayesian modeling, probabilistic programming, causal inference, or formal methods for reasoning under uncertainty. Experience building agentic, active-learning, closed-loop, or autonomous-science systems. Familiarity with biological data modalities such as single-cell omics, perturbation data, imaging, spatial profiling, genetics, or multi-omics. Experience designing systems that generate, rank, test, or revise scientific hypotheses. Background in philosophy of science, epistemology, scientific methodology, or formal argumentation. Experience integrating computational predictions with experimental or automated lab workflows. Track record of publishing or presenting work at premier ML, computational biology, or scientific venues. Compensation We offer competitive base compensation with bonus potential and generous early‑stage equity. Your final offer will reflect your background, expertise, and expected impact. U.S. Benefits Full‑time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer‑paid life and disability insurance; flexible time off with generous company‑wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike‑share memberships for office‑based employees; and a company‑subsidized lunch program. International Benefits Full‑time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market. Expected Base Salary Range

$268,000 – $336,000 USD

About LILA Lila Sciences is building Scientific Superintelligence™ to solve humankind’s greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard‑coding expert knowledge into tools, LILA builds systems that can learn for themselves. LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you’d love to work in, even if you don’t meet every qualification listed above, we encourage you to apply. We’re All In Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy. A Note to Agencies Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto. #J-18808-Ljbffr Lilasciences