Staff Software Engineer
HeartFlow
Staff Software Engineer
San Francisco, California
Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFR CT Analysis—provides a color-coded, 3D model of a patient's coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFR CT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.
Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide.
This position will play a pivotal technical leadership role in realizing Heartflow's vision of creating a single, comprehensive platform to manage heart disease. As a Staff Software Engineer, you will lead the architecture and data modeling necessary to build a next-generation distributed system that seamlessly and securely integrates Heartflow's cloud services with complex, on-premise hospital Electronic Health Record (EHR) systems.
You will own the technical strategy and execution within the interoperability domain, elevating how clinical data is processed, modeled, and delivered. Operating at the staff level, you will drive architectural decisions across multiple components, mentor engineering teams, and establish robust software development best practices. You will ensure that the platform's foundation scales efficiently and strictly adheres to the compliance, security, and quality standards set forth by the FDA and other regulatory bodies.
Job Responsibilities:
- Lead Platform Architecture & EHR Integration: Architect and oversee the development of Heartflow's interoperability services. You will design the robust technical bridge between complex, on-premise hospital Electronic Health Record (EHR) systems and our AWS cloud environment.
- Drive the Single Platform Vision: Define and execute advanced data modeling and persistence strategies. You will structure complex clinical data to realize our vision of a comprehensive, unified platform for managing heart disease.
- Own Mission-Critical Components: Direct the technical strategy and development of critical data acquisition and ingestion pipelines, ensuring the seamless, scalable, and secure extraction and normalization of patient data from diverse hospital networks.
- Build Enterprise-Grade APIs: Design highly reliable, secure, and low-maintenance APIs (leveraging REST alongside healthcare standards like FHIR and HL7) to securely connect on-premise hospital components to our cloud infrastructure.
- Champion Compliance & Security: Drive architectural decisions according to the highest software development best practices, ensuring all data flows and system integrations strictly adhere to the standards and guidance set forth by the FDA and other regulatory bodies.
- Provide Technical Leadership: Join a team of high-performing engineers on a mission to revolutionize precision heart care. As a staff-level technical multiplier, you will mentor peers and guide system design.
Skills Needed:
You have experience in the following:
- Software Engineering & Architecture: Expert-level Python development, applying Domain-Driven Design (DDD) principles, and architecting robust microservices and event-driven architectures at scale.
- Healthcare Interoperability: Integrating with Electronic Health Record (EHR) systems and utilizing healthcare data standards (e.g., FHIR, HL7).
- Data Strategy: Advanced data modeling and architecting scalable persistence layers for complex, high-volume data systems.
- Cloud & Connectivity: Building within modern cloud ecosystems and designing enterprise-grade, highly secure RESTful APIs.
- Technical Leadership: Mentoring high-performing engineers, driving system design, and establishing rigorous software development best practices and testing strategies.
- Quality Assurance: Designing testable systems and leading comprehensive testing strategies (Unit, Functional, and System-level) for mission-critical applications.
You are passionate about:
- Platform Vision: Realizing the vision of a single, unified platform to manage and treat heart disease.
- Engineering Excellence: Championing high-quality software, rigorous development processes, and elevating the technical baseline of the entire team.
- Strategic Ownership: Taking end-to-end ownership of complex architectural domains and operating independently with a high degree of latitude.
- Constructive Collaboration: Fostering a culture of open communication, speaking up when faced with challenges, and guiding healthy technical debates.
- Innovation: Pragmatically evaluating and introducing state-of-the-art technologies to solve complex interoperability and scaling challenges.
You are excited to dive deeper into:
- Domain Expertise: Advancing the frontier of Software as a Medical Device (SaMD) and data acquisition in the cardiology space.
- Regulatory Innovation: Navigating and innovating within strict regulatory environments (FDA, HIPAA) to securely deliver life-saving medical applications.
- System Resilience: Solving novel challenges in distributed, highly available, and resilient systems for mission-critical healthcare operations.
Educational Requirements & Work Experience:
- Bachelor's degree in Computer Science, Engineering, or related discipline, or equivalent experience.
- 10+ years of relevant industry experience
A reasonable estimate of the base salary compensation range is $190,000 to $250,000, bonus, and equity.
Heartflow is an Equal Opportunity Employer. We are committed to a work environment that supports, inspires, and respects all individuals and do not discriminate against any employee or applicant because of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. This policy applies to every aspect of employment at Heartflow, including recruitment, hiring, training, relocation, promotion, and termination. Positions posted for Heartflow are not intended for or open to third party recruiters / agencies. Submission of any unsolicited resumes for these positions will be considered to be free referrals. Heartflow has become aware of a fraud where unknown entities are posing as Heartflow recruiters in an attempt to obtain personal information from individuals as part of our application or job offer process. Before providing any personal information to outside parties, please verify the following: A) all legitimate Heartflow recruiter email addresses end with "@heartflow.com" and B) the position described is found on our careers site at
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