Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Product Engineer - Evinova

AstraZeneca

The RoleWe are looking for a pragmatic builder-architect — a senior engineer who ships fast without leaving a mess, and makes architectural choices that hold up as the product scales. This is a hands-on technical leadership role: roughly 40% writing code and prototyping, with the remainder spent on architecture, mentoring, and raising the engineering bar within your team.You will embed with a product team for extended periods, owning technical direction and building AI-powered features end-to-end — from idea through production. You won’t just advise; you’ll build, and what you build will set the pattern for others. You may end up managing some engineers.Most engineers lean one way. “Hackers” ship fast but accrue debt; “architects” build clean abstractions but stall on delivery. You are both. You know when to prototype loosely and when to invest in the durable version — and you can articulate why.What You’ll DoDesign and build AI-powered product features — agent architectures, RAG pipelines, model orchestration, evaluation frameworks, and guardrails — with the same engineering rigor as any production system: testable, observable, gracefully degrading.Own the full stack for the features you build — application code, data, infrastructure — making end-to-end decisions about deployment, observability, cost, and security.Make architectural choices that optimize for reversibility early and durability when the problem is actually understood.Mentor and coach engineers on your team, transferring judgment and mental models, not just answers. Calibrate involvement to stakes: get out of the way for cheap-to-reverse work, lean in for load-bearing decisions.Read existing systems as accumulated knowledge before treating them as debt. Understand why things are shaped the way they are before proposing changes.Identify and manage the blast radius of technical decisions — the dangerous ones at this level aren’t bad deployments, they’re bad directions.What We’re Looking ForEngineering JudgmentYou think in failure modes and second-order effects, not happy paths and demos. “Who inherits this, and what does it cost them if I’m wrong?” is a question you ask naturally.You optimize for sustainability — testability, clear boundaries, sane defaults, documentation — so what you build can be owned and extended by others.You treat constraints as the design problem. You map what’s frozen, what’s validated, what other systems depend on, and what can’t take downtime before proposing solutions.AI EngineeringYou have built and shipped AI-powered features in production — not just used AI tooling for personal productivity.You treat AI systems as engineering problems: versioned, evaluated, observable, and designed to degrade gracefully when models behave unexpectedly.You use AI as a force multiplier on judgment you already have — it accelerates the parts you understand well, precisely because you can evaluate the output.You use AI to compress the learning loop, not skip it. You build real mental models of new technology, using AI as an accelerant, not a crutch.Working with TeamsYou transfer judgment, not just answers. You surface reasoning, install mental models, and make yourself progressively less necessary.You lead through demonstrated competence, not positional authority — and you know that doing the work yourself is sometimes the failure mode.You learn the team’s context, constraints, and history before injecting opinions. You earn trust by understanding what came before.LearningYou learn to a depth proportional to the decision. Evaluating something? Defensible opinion, move on. Committing the product to it? Deep enough to understand failure modes and sharp edges.When you pick up new technology, you’re trying to understand why it works the way it does and what problem its designers were solving — because that’s what transfers.Technical EnvironmentOur stack spans the following. We don’t expect mastery of all of it — but given the role, you should be able to pick up almost any of it quickly.Cloud: AWS (primary) — architecture and infrastructureFront-end: React, TypeScript, Vite, Tailwind, shadcn/ui, BlockNote, NginxBack-end: Node.js, Next.js, Python, Kafka, FastAPI, Dramatiq + Valkey (task queue), PynamoDB (single-table DynamoDB), SQLAlchemy async + asyncpg (PostgreSQL), Prometheus, MongoDBInfrastructure: Docker, Kubernetes (EKS), AWS CDK (TypeScript), ECS Fargate, DynamoDB, S3, RDS, Elasticache Valkey, Bedrock, Secrets Manager, SSMDevOps: NX, pnpm, GitHub Actions, GHCR, Docker/Buildx, Wiz, GitHub OIDCAI Infrastructure: Google ADK, LiteLLM, OpenRouter, Bedrock (KB, BDA, Guardrails), MCP, Langfuse + OpenTelemetry, RAGAS, specialist domain agentsAI Tooling: Claude Code, Cursor, Copilot, opencode, Hermes AgentRequirementsBachelor's DegreeMinimum 8+ years of experience in software engineering, with meaningful time spent at a senior/staff/principal level owning technical direction.Production experience building AI-powered features — agent systems, RAG, model orchestration, or similar. Not just prompting or fine-tuning in isolation.Strong full-stack capability — comfortable across application code, data stores, and infrastructure. You don’t need to be an expert in all three, but you can’t treat any of them as someone else’s problem.Experience with AWS at scale — you’ve designed, deployed, and operated production systems on AWS, not just used it for personal projects.Demonstrated ability to mentor and elevate other engineers — through pairing, design review, or informal technical leadership.Nice to HaveExperience in regulated industries (healthcare, pharma, finance) where compliance constraints shape technical decisions.Background building multi-agent or agentic AI systems in production.Familiarity with infrastructure-as-code (CDK, Terraform, Pulumi) and container orchestration (EKS, ECS).Experience working in product-led engineering organizations where engineers own outcomes, not just outputs.When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.The annual base pay for this position ranges from $172,466.00 - $258,700.00 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.Are you ready to bring new insights and fresh thinking to the table? Fantastic! We have one seat available, and we hope it’s yours. Apply today.Date Posted08-Sep-2026Closing Date21-Sep-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.SummaryLocation: US - Gaithersburg - MDType: Full time

Vacancy posted 25 days ago
Similar jobs that could be interesting for youBased on the Principal Product Engineer - Evinova in Gaithersburg, MD vacancy
  • $144.65k - $216.97k

    WHY JOIN US?Evinova is a health-tech business focused on accelerating better health...  ...meaningful connection.Introduction to Role:As Principal AI Engineer, you'll design and implement...  ...ultimately patient careCollaborate with product teams, clinical experts, and ML engineers... 
    Suggested
    Full time
    Temporary work
    Work at office
    Worldwide
    3 days per week

    AstraZeneca

    Gaithersburg, MD
    9 days ago
  • $18 - $50 per hour

     ...simulation- helping innovative global manufacturers design better products, faster! With the resources of a large company, and the energy...  ...Position Overview: As a Thermo-Mechanical Product Engineering Intern , you will support the development and application of... 
    Suggested
    Remote job
    Hourly pay
    Full time
    Internship
    Work at office
    Local area

    Siemens

    Rockville, MD
    4 days ago
  •  ...represent X-energy directs you in a manner otherwise, please contact us at .Job DescriptionThis role is responsible for performing engineering tasks associated with selecting, qualifying, and conducting lifetime assessment analyses for materials in a nuclear reactor or... 
    Suggested
    Full time
    Work at office

    X Energy

    Rockville, MD
    2 days ago
  • $122.31k - $183.47k

    AstraZeneca is seeking an experienced principal process engineer for our cell therapy Global Manufacturing Science and Technology (MS&T) team....  ...teams to ensure successful commercialization of cell therapy products; represent Manufacturing Operations on product CMC teams,... 
    Suggested
    Temporary work

    Socket.dev

    Gaithersburg, MD
    5 days ago
  • $269k - $328.9k

     ...are looking for an experienced Executive Director of Process Engineering to lead our cell therapy process engineering team. The Executive...  ...out a team. You will help ensure that our cell therapy products are manufactured, cost-effectively, from early development through... 
    Suggested
    Full time
    Work at office
    3 days per week

    AstraZeneca

    Gaithersburg, MD
    10 hours ago
  • $18 - $50 per hour

     ...simulation- helping innovative global manufacturers design better products, faster! With the resources of a large company, and the energy...  ...Position Overview: As an Electronics Reliability Product Engineering Intern , you will support the development of Simcenter Simlab... 
    Remote job
    Hourly pay
    Full time
    Internship
    Work at office
    Local area

    Siemens

    Gaithersburg, MD
    4 days ago
  • Company DescriptionCRB is a leading provider of sustainable engineering, architecture, construction and consulting solutions to the global life sciences and food and beverage industries. Our more than 1,200 employees provide best-in-class solutions that drive success and... 
    For subcontractor
    Work at office

    CRB

    Rockville, MD
    10 hours ago
  • $134.33k - $181.35k

     ...Job Summary This is a fully in-person role located in Germantown, Maryland. We are seeking a Principal Systems Engineer to contribute to new and evolving radar products by defining requirements, shaping system architecture, and planning verification and validation... 
    Contract work
    Work experience placement
    Local area
    Relocation
    Flexible hours
    Shift work

    Leonardo DRS

    Germantown, MD
    3 days ago
  • $131.3k - $237.35k

     ...Leidos is seeking a Principal Systems Engineer (LEAD) to join the Air Traffic Business Area within the Homeland Sector, supporting the development...  ...software engineering practices that improve developer productivity, code quality, testing, and delivery.Core Technical... 
    Full time
    Remote work

    Leidos

    Gaithersburg, MD
    1 day ago
  • $119.94k - $161.92k

     ...Relocation: Available Career Functional Area: Engineering Schedule: 9/80 Shift: 1st About the Role We're hiring a Principal Test Engineer to lead our test engineering...  ...test procedures and protocols that verify products meet performance specifications Conduct... 
    Contract work
    Work experience placement
    Local area
    Relocation
    Flexible hours
    Shift work

    Leonardo DRS

    Germantown, MD
    5 days ago
  • $185k - $207.5k

     ...please contact us at .Job DescriptionOur Heat Exchanger Design Engineer is responsible for the engineering design and development of...  ...ensure the development of the systems and components through production including any necessary prototyping, testing, and commissioning... 
    Full time
    Internship
    Work at office

    X Energy

    Rockville, MD
    1 day ago
  •  ...become part of a global team of over 50,000 planners, designers, engineers, scientists, digital innovators, program and construction...  ...world. Join us.Job DescriptionAECOM is seeking a highly talented Principal Geotechnical Dam Safety Engineer to join the East Region Dams... 
    Contract work
    Part time
    Local area
    Remote work
    Worldwide
    Flexible hours

    AECOM

    Germantown, MD
    2 days ago
  •  ...CRB Group seeks an Entry-Level Process Engineer in Rockville, MD to assist in designing manufacturing facilities and equipment, supporting infrastructure and critical utility systems. You will perform engineering calculations, balance material and energy, and contribute... 

    CRB Group

    Rockville, MD
    1 day ago
  •  ...some of the most powerful facilities in the world - those that change people's lives. We are the leading provider of sustainable Engineering, Architecture, Construction and Consulting solutions to the global life sciences and food and beverage industries. Our employees... 
    Work at office

    CRB

    Rockville, MD
    16 hours ago
  •  ...Job Description Job Description Job Title: PCB Design Engineer Location: Germantown, MD onsite Responsibilities Develop PCB layouts from released schematics, netlists, and engineering requirements with minimal oversight. Perform component placement and... 
    Local area

    System One

    Germantown, MD
    28 days ago
  •  ...and AdenoVerse™ immunotherapies to patients. We have multiple products being evaluated in the clinic using our innovative manufacturing approach to cell and gene therapies.We are seeking a Process Engineer - Drug Substance Manufacturing to support the Precigen, Inc. drug... 
    Work at office

    Precigen

    Germantown, MD
    2 days ago
  • $100k - $120k

    PCB Design Engineer Germantown, Maryland ID: j-2807 JOB TYPE: Direct Hire COMPENSATION: $100000 - $120000 / yr Staffing Pros, a division...  ...- lead hardware development for satellite communication products end-to-end, from concept to production and beyond. Drive innovation... 
    Full time
    For contractors

    Veterans Enterprise Technology Solutions Inc

    Germantown, MD
    3 days ago
  • $100k - $125k

     ...requirements, and program/project requirements. Additionally, this role oversees the implementation of rigorous, repeatable Fire Protection Engineering processes, ensures technical integration, monitors risks, and provides system-level oversight and support. The position is... 
    Full time
    Contract work
    Work at office
    Remote work

    X Energy

    Rockville, MD
    10 hours ago
  • $213.75k - $242.5k

     ...Plant Support Systems, Physical Plant Integration, and Systems Engineering disciplines. The Director sets the vision, technical standards...  ...leadership and cross-functional teams, including development, product, and operations, to define enterprise integration requirements... 
    Full time
    Work at office

    X Energy

    Rockville, MD
    4 days ago
  • X Energy, LLC is seeking a Heat Exchanger Design Engineer in Gaithersburg, MD to lead mechanical design and development of SSCs for nuclear products. The role covers concept development, analysis, prototyping, and commissioning to meet stringent specifications. The position... 
    Work at office

    X-energy

    Rockville, MD
    3 days ago
  • $120k - $145k

     ...Job DescriptionX-energy LLC is hiring a HVAC Mechanical Design Engineer to support a Plant & Process Design team. This role is responsible...  ...technical problems and deliver high quality engineering work products on time and within budget.Perform other duties as assigned by... 
    Full time
    Contract work
    For subcontractor
    Work at office

    X Energy

    Rockville, MD
    10 hours ago
  • CRB is seeking an AIC Engineer III to oversee discipline budgets and coordinate with clients, engineers, and vendors on small to medium projects. The role emphasizes delivering design across programming, feasibility, and detailed design phases, and may lead automation... 

    CRB

    Rockville, MD
    5 days ago
  •  ...Overview Project Engineering Manager - Water/Wastewater. About the job Project Engineering Manager - Water/Wastewater The Opportunity...  ...and quality control across disciplines. Coordinate and direct production teams while serving as the responsible engineer in charge. Client... 
    Flexible hours

    SolveNow Inc.

    Gaithersburg, MD
    5 days ago
  • $122.31k - $183.47k

     ...Job Description AstraZeneca is seeking an experienced Principal Process Engineer to support late-phase process development, process characterization...  .... The role will partner with Drug Substance, Drug Product, Analytical Sciences, Quality, Regulatory Affairs, Manufacturing... 
    Hourly pay
    Temporary work
    Gaithersburg, MD
    20 days ago
  • $112.3k - $168.46k

     ...looking for a highly motivated and experienced Senior Process Engineer for Viral Vector Upstream Process Development. The candidate will...  ...& Scale Translation : Execute unit operations across seed, production, and harvest interfaces; support scale-up strategies from... 
    Hourly pay
    Temporary work
    Gaithersburg, MD
    7 days ago
  • $220k - $240k

     ...claiming to represent X-energy directs you in a manner otherwise, please contact us at .Job DescriptionThe Director, Value Engineering and Product Management at X-energy will work cross functionally across Project Controls, Engineering, Procurement / Supply Chain, Construction... 
    Full time
    Temporary work
    Work experience placement
    Work at office
    Monday to Friday

    X Energy

    Rockville, MD
    1 day ago
  •  ...Management Solutions for Technical Assistance to Support Design Engineering Inspections Services on behalf of The U.S. NRC - HQ...  ...participates in the e-Verify program)Proficient with Microsoft Office Products (Microsoft Word, Excel, PowerPoint, Publisher, & Adobe)Other DetailsWork... 
    Full time
    Contract work
    For contractors
    H1b
    Work at office
    Flexible hours

    Prosidian Consultng

    Rockville, MD
    1 day ago
  • $103.29k - $154.93k

     ...Senior Process Engineer, Manufacturing Sciences & Technology, Cell Therapy: Location: AstraZeneca, Rockville, MD   Travel: Up to...  ...effective manufacturing of clinical and commercial cell therapy products.   Responsibilities include leading on-the-floor / hands-on... 
    Hourly pay
    Full time
    Temporary work
    Shift work

    AstraZeneca

    Rockville, MD
    1 day ago
  •  ...important issues such as food scarcity and global health.Job DescriptionAbout the RoleThe Lead Automation, Instrumentation, & Controls Engineer is responsible for overseeing the discipline at a project level and managing the project discipline budget on simple to complex... 

    CRB

    Rockville, MD
    4 days ago
  • $106.4k - $149k

     ...process. If anyone claiming to represent X-energy directs you in a manner otherwise, please contact us at .Job DescriptionCombine your engineering knowledge and business insights, to vet engineering services, equipment designers and fabricators to help develop a supplier... 
    Full time
    Contract work
    Work at office

    X Energy

    Rockville, MD
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Product Engineer - Evinova. Be the first to apply!