Fractional Controller

Fractional Controller – Biotechnology / Pre-IPO

Aphios Corporation North Reading, Massachusetts Area | Fractional / Consulting Job Code: APH-2605

Position Overview

Aphios Corporation, a clinical-stage biotechnology company advancing a diversified portfolio of therapeutic products and proprietary platform technologies, is seeking an experienced Fractional Controller to strengthen the Company’s accounting, financial reporting, internal controls, and audit readiness as Aphios advances its clinical programs, strategic partnerships, financing activities, and planned path toward the public markets.

This is a hands-on senior accounting position suited for an experienced Controller, Assistant Controller, CPA, or senior accounting professional who is comfortable working with an entrepreneurial biotechnology company while establishing the financial discipline and reporting infrastructure expected of a substantially larger organization.

The successful candidate should have strong accounting and financial reporting experience and familiarity with Sage accounting software or another accounting system capable of supporting GAAP-compliant financial reporting and robust internal controls .

Experience with NIH/SBIR funding, biotechnology accounting, financial audits, SEC reporting, IPO preparation, or public-company accounting is highly desirable.

Key Responsibilities

• Maintaining accurate general ledger, balance sheet, income statement, and cash-flow reporting
• Monthly, quarterly, and annual financial close
• Accounts payable, accounts receivable, payroll coordination, and cash-management oversight
• Bank and balance-sheet reconciliations
• Budget-to-actual reporting and financial analysis
• Maintaining appropriate accounting policies, procedures, documentation, and internal controls
• Preparing financial statements in accordance with U.S. Generally Accepted Accounting Principles (GAAP)
• Maintaining and improving the Company’s Sage accounting environment , or assisting with migration to or implementation of an appropriate scalable accounting system
• Preparing schedules and supporting documentation for independent financial statement audits
• Working with external accountants and auditors to maintain GAAP-compliant, audit-ready financial records
• Supporting development of accounting controls and reporting practices appropriate for an organization preparing for potential SEC reporting and public-company requirements
• Assisting management with financial information required for financing, investor, strategic partnership, and due-diligence activities
• Supporting accounting across Aphios Corporation and affiliated entities as appropriate

NIH / SBIR Experience – Highly Desirable

Aphios has a significant history of federally funded research and development. Experience with NIH, SBIR/STTR, or other federal grant accounting would therefore be particularly valuable.

Relevant experience may include:

• Tracking grant expenditures and allowable costs
• Direct and indirect cost allocation
• Project and grant-level accounting
• Payroll and labor allocationFinancial reporting and documentation supporting NIH awards
• Audit-ready documentation of federally funded expenditures
• Familiarity with applicable federal grant accounting and compliance requirements

Pre-IPO / Public Company Experience – Preferred

As Aphios strengthens its financial infrastructure in anticipation of future capital formation and potential entry into the public markets, additional value would be placed on experience involving one or more of the following:

• GAAP-compliant financial reporting and external audits
• IPO, direct listing, reverse merger, SPAC, or other public-market transactions
• Public-company accounting and reporting practices
• SOX/internal-control development or implementation
• Audit Committee interaction
• Equity, stock-based compensation, and capitalization accounting
• Investor, financing, and transaction due diligence

Qualifications

Required

• Bachelor’s degree in Accounting, Finance, or related discipline
• Significant hands-on accounting and financial reporting experience
• Strong knowledge and practical application of U.S. GAAP
• Experience with Sage or comparable accounting/ERP software
• Experience preparing for and supporting independent financial audits
• Ability to operate independently in a small-company environment while maintaining institutional-quality financial discipline

Preferred

• CPA or equivalent senior accounting credentials
• Controller, Assistant Controller, Audit Manager, or equivalent senior accounting experience
• Biotechnology, pharmaceutical, life sciences, or technology-company experience
• NIH/SBIR/STTR or federal grant accounting experience
• Pre-IPO or public-company accounting experience
• SEC reporting and SOX familiarity
• Experience working with independent auditors and Audit Committees
• Experience establishing or upgrading accounting systems, policies, controls, and financial reporting infrastructure for a growing company

Position Structure

This is initially envisioned as a Fractional or consulting position , with hours and structure determined based on the candidate’s experience and Aphios’ evolving requirements.

The role could expand as the Company’s clinical programs, financing activities, strategic partnerships, and public-market preparations progress.

About Aphios

Aphios Corporation is advancing a portfolio that includes a planned Phase 3 clinical program for Zindol® , planned Phase 2b programs in opioid addiction and chronic epilepsy , and additional therapeutic programs progressing through IND-enabling development.

Aphios combines clinical-stage assets with proprietary pharmaceutical and nanotechnology platforms and is pursuing strategic partnerships, institutional financing, and longer-term public-market opportunities.