Medical Director, AI Safety
$175k - $200kAvo
Avo is the leading AI platform for healthcare enterprises, helping clinicians make better decisions, move faster, and improve the quality of patient care. Serving as a central hub for care teams, Avo brings together patient data, clinical knowledge, and AI-powered workflows to support diagnosis, care planning, documentation, orders, and evidence-based decision-making at the point of care. Clinicians today navigate dozens of tabs, applications, datasets, hospital protocols, medical guidelines, and payer policies to deliver high-quality care. Avo changes that. We are product-obsessed, collaborative, and scrappy, united by a mission to improve healthcare delivery through AI. Our investors include Noro-Moseley Partners, AlleyCorp, Scrub Capital, and several leading hospitals and universities. The Role We are seeking a Medical Director, AI Safety that will own the safety of Avo's AI-generated clinical content. That means deciding what "safe enough to ship" means for a discharge summary, a pre-visit summary, or a decision-support module, building the tests that enforce it, and signing off before it reaches a clinician. You will design the grading rubrics, run the evaluations, classify failures by clinical severity, and turn the findings into changes the Studio and engineering teams make. Roughly 85% of your time goes to safety. The remaining 15% splits two ways: building clinical modules yourself in Avo's Studio, so your safety judgments are grounded in how the content is actually produced, and joining sales and customer conversations as the physician who can explain how we test and why a CMIO should trust the output. You report to the CMIO, with a dotted line to the Chief Commercial Officer. What You'll Do AI safety (core of the role) Define the safety standard for each product line: what counts as a hallucination, an omission, or a clinically material error, and how severe each is Design and run evaluation protocols for clinical AI modules, including hallucination detection, omission analysis, and accuracy checks against source records and evidence-based guidelines Build and maintain a clinical harm taxonomy and grading rubric (NCC MERP-style severity scoring) and apply it across benchmark sets Review AI-generated clinical content directly, and grade the automated graders so we know when to trust them Own the release gate: write the go/no-go safety assessment for new modules and major prompt or model changes Investigate reported clinical errors from customers, trace root cause, and drive the fix through Studio and engineering Write the safety reports, validation summaries, and white papers that buyers and their clinical governance committees ask for Track the regulatory and standards landscape for clinical AI (FDA, ONC, CHAI, Joint Commission) and translate it into internal requirements Clinical builder (~5-10%) Build or revise clinical modules in Avo's Studio, applying evidence-based guidelines and your own practice experience Feed what you learn from building back into the safety protocols, and vice versa Join prospect calls and pilot evaluations as the physician who can speak to how Avo's content is validated Present the safety program to CMIOs, CIOs, and clinical quality leaders, and answer their hardest questions about failure modes Challenge the status quo in the room: name where legacy documentation and CDS workflows fail patients, and show how a tested AI alternative does better What You Bring Active clinical license (MD/DO, NP, or PA) with hands-on patient care experience 3-7 years of clinical practice; you can read a discharge summary and spot the missed anticoagulation plan in under a minute Experience with or strong interest in clinical AI, CDS, or health informatics A testing mindset: you like designing the rubric, arguing about edge cases, and finding the error nobody else caught Ability to write a clear, defensible safety report for a clinical governance committee Comfort presenting to C-suite clinical leaders and answering pointed questions about AI failure modes Willingness to define the role's scope as the product and company grow *Travel: Some travel expected for customer meetings and demos, up to 10% Nice to Have Experience with EHR systems (Epic, Meditech, Athena) Background in clinical informatics, quality improvement, or patient safety Prior experience in a sales engineering, solutions, or customer-facing clinical role Familiarity with AI/LLM evaluation methodologies Why Join Avo Impact: Avo’s products run inside hospitals, helping clinicians make better calls at the point of care. The work is real, and the mission is meaningful. Ownership: We have a bias for action; you'll work alongside teams who take initiative, follow through on commitments, and take accountability for results. High Agency: We move fast, trust our people, and avoid bureaucracy. Great Team: Work alongside a talented, low-ego group of clinicians, engineers, and product folks who care deeply about craft. Remote-First: Work from anywhere in the US. The company has offices in NYC, so if you’re in the area we’d love the chance to work in-person together 2 days/week. How We Take Care of Our Team Generous Time Off: Flexible and generous PTO Comprehensive Health Plans: Medical, dental, and vision coverage for you and your family 401K Matching: Contribution matching to help invest in your future Personal Device Allowance: Tax-free funds for personal device usage Compensation and Equity: $175,000 - $200,000 OTE and equity #J-18808-Ljbffr Avo
- Avo is hiring a Medical Director, AI Safety to own safety of AI-generated clinical content and set the bar for what is safe to ship. You’ll design grading rubrics, run evaluations, and sign off before clinicians see output. You’ll also split time building clinical modules...SuggestedRemote job
- Alphanumeric is supporting a leading pharmaceutical company in filling a contract Medical Director - Drug Safety. This is a full-time, 1-year contract with potential extension, and 100% remote work with base in Brazil. You will lead safety evaluation and benefit-risk assessments...SuggestedRemote jobFull timeContract work
- Sr. Medical Director - Drug Safety and Pharmacovigilance (Remote) job at Legend Biotech USA, Inc.. United States. Company Information Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in...SuggestedRemote jobContract workLocal areaFlexible hours
- Lead safety evaluation and benefit-risk assessments for assigned products. Support pharmacovigilance and risk management activities across clinical development and marketed products. Contribute to regulatory submissions and health authority interactions. Qualifications...SuggestedRemote jobFull timeContract work
- BeOne is seeking a Senior Medical Director to serve as Lead Product Safety Physician for multiple developmental programs, providing a unified interpretation of global safety data and guiding safety communication to internal teams and external regulators. The role requires...Suggested
- ...ResponsibilitiesSafety Leadership and Risk ManagementLead site Safety Committees and partner with leaders at all... ...course.First Aid, CPR, and emergency medical response training/certification.Work... ...everyone’s unique perspective.Use of AI in Hiring As part of the recruiting...Full timeWork at officeLocal areaWeekend workDay shiftAfternoon shift
- Torsap Thai Kitchen seeks an experienced Director of Engineering, Trust & Safety to lead the technical strategy and platforms safeguarding its global user base. You will oversee real-time risk, ML pipelines, and automated enforcement while preserving a seamless user experience...
$298.2k - $368.2k
...motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. The Senior Medical Director serves as the Lead Product Safety Physician for multiple or large complex strategically important developmental programs (often multi-indication...Hourly payLocal areaImmediate startFlexible hoursShift work- A digital health company in New York seeks a Medical Director to lead virtual care initiatives and design clinical pathways. The ideal candidate... ...with product teams to enhance care pathways, employing an AI-native approach to improve efficiency and service quality. Strong...
- Devoted Health is seeking a physician leader to design and scale a national Musculoskeletal (MSK) program built on our AI platform. You will practice the medicine you design while shaping care pathways and patient experience. You will build and lead a team of clinicians...
- Accenture Edge for AWS is seeking a Tech Practice Leader - Data and AI to build and lead the practice serving mid-market companies up... ...offers a market competitive suite of benefits including medical, dental, vision, life, and long-term disability coverage, a 401(...Full timeWork experience placementLive inWork at officeLocal area
- ...the SVP, Global Engineering and Infrastructure, the Senior Director of Health & Safety Operations Europe serves as a strategic leader driving safety... ...growth and succession planning. Pioneer the use of AI and emerging technologies as accelerators for continuous improvement...Local areaImmediate start
$216k - $288k
...changing therapies to patients faster. We are seeking a Senior Director of AI & Data Science to help shape that future by creating AI... ...you need when it matters most and provides benefits, including medical, dental, life and disability insurance, 401(k) matching, family...Work at officeLocal areaFlexible hours- DescriptionThe Mount Sinai Health System is seeking a Medical Director of Acute Care Psychiatry for Mount Sinai Behavioral Health Center. The... ...Services and MSBI Site Chair for clinical care and quality/safety initiatives.Located on the Lower East Side, the Center offers...Full timeTraineeshipLive inLocal area
- DescriptionThe Mount Sinai Health System is seeking a full-time psychiatrist to serve as the Medical Director of Behavioral Health Services in the Institute for Advanced Medicine (IAM) and the Center for Transgender Medicine and Surgery (CTMS).The Institute for Advanced...Full timeTraineeshipWork at officeLocal area
$250k - $290k
...sector expertise, paired with innovative AI-powered technology and an investor mindset... ...your future with confidence.As a Senior Director in EY-Parthenon’s Strategy & Execution -... ...addition, our Total Rewards package includes medical and dental coverage, pension and 401(k)...Work experience placementSummer holidayWork at officeFlexible hours3 days per week- ...initiatives. \n Evaluate and advance emerging technologies, including AI-enabled capabilities and automation opportunities. \n... ...\n Premium Health Notable Benefits: \n \n Paid Time Off, Medical, Dental and Vision plans, Retirement plans \n Public Service...Full timeTemporary workWork at officeRemote workMonday to Friday2 days per week
- ...CVS Health is seeking a Director in Analytics & Behavior Change to lead the creation, launch, and maintenance of an AI-powered clinical data insights platform powering automation and clinician workflows. You will collaborate with Data Science, Engineering, and cross...
$115.49k - $192.33k
...Description The mission of the Patient Safety and Quality department within the Mount Sinai Institute of Critical Care Medicine (ICCM... ...collaborative relationships with nursing staff, leadership, medical staff and other administrative staff. Monitor quality performance...Full timeTraineeshipLocal area- ..., move, health plan, and life stage. Our AI-native platform helps us deliver personalized... ...self-guided tools, coaching, therapy, medication management, and specialty care. With... ...role and our mission. The Lead PM, AI Safety and Platformwill drive the product roadmap...Full timeWork at officeWorldwideRelocation2 days per week3 days per week
- Alignerr seeks a Clinical Business Intelligence Manager to drive analytics for AI training initiatives in a remote, contract role. You will lead a BI team, shape analytics infrastructure, and translate complex clinical data into actionable insights that inform AI models...Remote jobContract work
$100 per hour
Ethos is seeking directors of clinical development to help train an AI model on professional documents, spreadsheets, and slide decks. The role focuses on clinical... ..., investigator brochures, regulatory modules, medical affairs slides, and publication plans. The engagement...Hourly payImmediate startRemote workFlexible hours- Lilly seeks a Director, AI Evidence Registry to build and maintain a structured, AI-ready corpus of clinical evidence for Lilly medicines, designed for human readers and large language models. You will set the structure, standards, and quality controls powering the program...
- DescriptionThe Mount Sinai Adolescent Health Center seeks a Medical Director for its School Based Health Centers. Description Job Title: Medical Director School Based Health CentersGrade: FacultyReports to: Division Chief, Adolescent Medicine, Mount Sinai Adolescent Health...Full timeTraineeshipLocal areaFlexible hours
- AuraOne, Inc. seeks a Medical Communications Manager for remote evaluation of AI outputs that touch clinical review. You will assess differential reasoning, dosing logic, and guideline adherence, flag patient-safety issues, and document corrected reasoning for model improvement...Remote job
- Obsidian is seeking an experienced Clinical Documentation Integrity Manager to improve AI tools enhancing clinical documentation accuracy and coding integrity. You will lead CDI programs, ensure compliance with regulations, and educate clinical staff on best practices....Remote job
$120k - $160k
...technology have finally made it possible for AI to impact clinical care in a meaningful... ...’ll do:We're looking for a Clinical Data Director who will be responsible for setting the... ...incentive compensation, restricted stock units, medical and other benefits depending on the...Full timeFlexible hours- SpaceXAI is seeking an experienced Safety Integrity Program Manager, Harmful Activity, to lead priorities, measures, and system health across upstream and downstream operations. You will translate policy, legal constraints, and technical requirements into practical workflows...
- Alice is seeking a seasoned researcher-leader to helm AI safety benchmarks and evaluations. You will own the taxonomy, harness, and release cadence, coordinating researchers and freelancers while reporting to the CTO office. You will influence the public research agenda...FreelanceWork at office
- ...Slingshot AI in New York is seeking a hands-on Product Manager to help bring Ash to more people through partnerships. You’ll span with partner teams, engineering, design, and clinical staff to integrate Ash into workflows and measure outcomes. You’ll work with our...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Medical Director, AI Safety. Be the first to apply!
- medical product manager New York, NY
- healthcare facilities manager New York, NY
- clinical supervisor lmft lcsw New York, NY
- behavioral health supervisor New York, NY
- clinical program manager New York, NY
- lead clinical data manager New York, NY
- assistant clinical director New York, NY
- associate medical director New York, NY
- occupational health manager New York, NY
- director behavioral health New York, NY



