Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior IT Infrastructure & Operations Manager

myDNA, Inc.

Senior IT Infrastructure & Operations Manager Our Purpose Our mission is to build a healthier and more connected world with precision health and genealogy services. We empower individuals with actionable insights into their genetic makeup, fostering a deeper understanding of their ancestry, health, and wellness. By integrating the experience of Gene by Gene Laboratory Services, FamilyTreeDNA genealogy, and myDNA reporting services, we strive to deliver cutting‑edge genetic testing and personalized solutions that inspire informed decisions and enhance quality of life. Our team is dedicated to advancing the field of genomics through innovation, research, and a commitment to excellence. Our Values All employees are expected to demonstrate our values of Innovate , One Team , and Integrity when carrying out the accountabilities and responsibilities of their role. This is how we show up every day for ourselves, our colleagues and our customers and strategic partners to deliver our vision and strategic goals. Position Overview The Senior IT Infrastructure & Operations Manager will own and scale the internal technology infrastructure, IT services and operations, ensuring that our labs, offices, and remote staff are running reliably and securely across the organization. This is a working manager role. Reporting to the Chief Information Technology Officer, you will own the day‑to‑day operation of our Systems team and forward direction of the IT service desk, systems operations, networking, cloud and data center environments. This role manages and maintains on‑call rotation for after‑hours coverage across the Infrastructure and Systems team for incident response. The role will be expected to translate business and technology objectives into resilient infrastructure, strong end‑user support, and a mature security posture, while managing the teams, vendors, and budgets that underpin these services. The Manager will act as a senior escalation point of accountability for uptime, internal end‑user experience, major incidents and security events and will partner closely with internal stakeholders to ensure technology enables, rather than constrains, business performance. In addition to broad business‑as‑usual responsibilities, this role will also provide opportunities to lead and contribute to interesting projects as required for a growing business. Equally important will be an aptitude for combining technical depth with commercial judgment to deliver dependable and cost‑effective operations, a flair for building highly collaborative working relationships, and the energy and drive to manage competing priorities in a growth‑focused and high‑performing corporate environment. Accountabilities and Responsibilities Systems & Infrastructure Operations Define the organization’s requirements, standards, and roadmap for on‑premises and cloud infrastructure, including compute, storage, virtualization, network, and identity. Ensure systems are designed and implemented for availability, performance, scalability, and recoverability in line with business requirements. Direct infrastructure portfolios, including upgrades, migrations, and capacity planning, ensuring delivery on time and within budget. Establish and govern configuration, patching, and lifecycle management standards across the server and platforms. Define, maintain, and oversee the testing of backup, disaster recovery, and business continuity capabilities. Strategically evaluate and recommend new technologies that improve reliability, efficiency, or cost. Fostering Team Success Model leadership and champion an institutional commitment to safety and risk mitigation in the workplace. Champion and align organizational directives with organizational values, procedures, and systems. Provide strategic leadership, development, and mentorship to the infrastructure, operations, service desk, and security teams. Set strategic objectives, manage performance frameworks, and build the capability and resilience of the team. Act with the mindset of a strategic business partner; collaborate and drive alignment when required to create win‑win outcomes and continuous improvement. Demonstrate agility and flexibility, steering the coordination of business activities or other duties as directed by executive leadership. Embrace and thrive in a changing environment, successfully navigating and leading through ambiguity. Enforce and uphold strict standards to ensure confidentiality is respected and always maintained. Cybersecurity & Information Security Collaborate in building out the cybersecurity program and work closely with cybersecurity lead to ensure appropriate cybersecurity risk mitigation. Run IT security operations, including identity, access, endpoint protection, patching, logging, and backups. Monitor, review, and implement vulnerability, patch, threat management, and logging programs, ensuring robust monitoring, detection, and timely remediation with appropriate technical parties. Govern identity and access management standards, including provisioning, privileged access, and periodic access reviews. Lead incident response, directing investigation, containment, and reporting efforts. Champion security awareness training and enforce acceptable‑use and information‑security policies. Creation and review of documentation, controls and evidence to support audits, cyber‑insurance requirements, and regulatory obligations (i.e. CAP/CLIA, HIPAA, GDPR, Australian Privacy Principles, etc.). Escalate material security risks and incidents to the Chief Information Technology Officer. Oversee the IT service desk to deliver responsive, high‑quality support against agreed service levels (SLAs). Manage incident, request, and problem management processes, driving root‑cause resolution and reducing recurring issues. Define and enforce end‑user computing standards, including hardware, software, and onboarding / offboarding frameworks. Govern performance intelligence, evaluate strategic service metrics and user satisfaction, and direct continuous‑improvement frameworks. Data Center & Network Operations Oversee the strategic operation, monitoring frameworks, and maintenance standards of data center and network environments, whether on premises, collocated, or in cloud. Ensure appropriate power, cooling, physical security, and environmental control frameworks are sustained and governed. Review and uphold network performance, connectivity, and resilience standards across sites, including LAN, WAN, wireless, and remote access. Direct capacity, redundancy, and lifecycle of data center, network, and hardware assets. Govern key vendors, service providers, and contracts to ensure value, performance, and accountability. Develop and manage the IT systems, infrastructure and operations budget, including capital and operating expenditure, and forecasting in partnership with Finance. Oversee the compliance and integrity of asset, license, and contract records. Compliance, Governance & Risk Partner with the compliance function to ensure infrastructure and operations comply with applicable regulations, policies, and contractual obligations. Establish and update IT policies, standards, and documentation, ensuring organizational readiness for internal and external audits. Identify, assess, and govern technology risks, authorizing controls to mitigate them. Position Requirements Skills & Knowledge Strong knowledge of enterprise operations and infrastructure: servers, virtualization, storage, networking, OS governance and identity (e.g., Windows Server, RHEL, Active Directory / IdM / FreeIPA, VMware / KVM, Group Policy, SSSD). Strong knowledge of IT service management practices (e.g., ITIL) and SLA‑based support delivery. Understanding of data center operations, networking (LAN / WAN / wireless), and backup / disaster‑recovery design. Exceptional skills in troubleshooting and performing root cause analysis. Solid understanding of cybersecurity principles, controls, and frameworks (e.g., NIST CSF, CIS Controls). Working knowledge of cloud platforms (e.g., AWS, OCI or Azure) and hybrid environments. Strong leadership, communication, and stakeholder‑management skills across all levels of the business. Ability to plan, prioritize, and deliver projects on time and within budget. Sound commercial judgment, including budget and vendor management. Excellent skills in Google Workspace or Microsoft Office 365. Experience with security tooling (SIEM, EDR, MFA, vulnerability management) is preferred. Experience managing managed service providers (MSPs) and colocation / data‑center providers is preferred. Experience Minimum 8 years of experience in IT infrastructure and operations, including at least 3 years in a leadership or supervisory role. Demonstrated experience managing infrastructure, service desk, and security functions. Proven experience leading infrastructure or cybersecurity programs. Ability to work autonomously in a dynamic and fast‑paced environment. Demonstrated ability to manage competing priorities and a diverse workload. Experience operating within high‑pressure situations and on‑call schedules. Experience in a regulated, healthcare, pharmaceutical, or FMCG environment is preferred. Previous exposure to mergers, integrations, or organizational change is preferred. Education Bachelor's degree in Information Technology, Computer Science, or a related discipline, or equivalent experience. Relevant professional certifications strongly preferred (e.g., ITIL, CISSP, CISM, AWS, Microsoft / Azure, CCNA / CCNP). Travel and Schedule Occasional, including travel across sites and data center facilities. Ability to work a standard shift of Monday – Friday, 8:00 AM – 5:00 PM. Based in the Houston area with the ability to work on‑site 3 days a week, plus flexibility for additional on‑site presence as needed for hands‑on management or critical incidents. Why Join Us At Gene by Gene, you’ll join a mission‑driven team advancing the science of genetics and discovery. You’ll have the opportunity to shape meaningful campaigns, tell compelling brand stories, and collaborate with talented professionals who share your passion for creativity, curiosity, and impact. Medical & Health Savings: Choice of 3 medical tiers generously sponsored by the company, with a monthly $50–$100 employer HSA contribution based on plan type and dependent level. 100% Covered Dental & Vision: No premium costs for employees or dependents. 401(k) Matching: Generous 50% company match up to 6% of annual base salary. Diverse PTO Framework: Structured time off incorporating vacation, sick leave, mental health days, personal days, company holidays, and a flexible floating holiday. Income Protection & Family Leave: Full company sponsorship of Short‑Term and Long‑Term Disability (STD/LTD) alongside Paid Family Leave offerings. #J-18808-Ljbffr myDNA, Inc.

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Senior IT Infrastructure & Operations Manager in Saint Louis, MO vacancy
  •  ...1 am CST. Responsibilities As an IT Manager on the Network Operations team, candidates will be responsible...  ...will have the chance to work with senior leaders in the organization, so collaboration...  ...of urgency to issues Network Infrastructure Oversight Provide overall... 
    Suggested
    Immediate start

    PTR Global

    Saint Louis, MO
    1 day ago
  • $120k - $150k

    Position Summary We are seeking an experienced Senior Manager of Infrastructure Protection Operations to strengthen the security and resilience of our enterprise...  ...equivalent experience). 7+ years of experience in enterprise IT infrastructure security, operations, or systems... 
    Senior
    Remote job
    Work at office
    Local area

    Focus Financial Consultants

    Saint Louis, MO
    5 days ago
  • PTR Global in St. Louis is seeking an IT Manager for the Network Operations team. In this leadership role, you will oversee daily operations, ensuring effective team performance and collaboration across various IT teams. Ideal candidates should have strong experience in... 
    Senior
    Night shift

    PTR Global

    Saint Louis, MO
    1 day ago
  • Enterprise Mobility is seeking an IT Manager for its Network Operations team to lead day-to-day operations and manage a team of network engineers. The position focuses on agility and continuous improvement in support of the company's technology strategy. The ideal candidate... 
    Suggested
    Remote job

    Enterprise Mobility

    Saint Louis, MO
    3 days ago
  • Hanson Professional Services Inc. is seeking a Senior Civil Site Engineer to join multidisciplinary design teams in delivering infrastructure projects across the industrial, site development, and transportation sectors. The role includes grading, storm water, rail and... 
    Senior

    Hanson Professional Services Inc.

    Saint Louis, MO
    1 day ago
  • A leading IT consulting firm is seeking a Senior Software Architect in St. Louis, MO. This role involves translating user requirements into software designs, creating architectural specifications, and collaborating with stakeholders. Candidates must have a background in... 
    Senior
    Remote work

    Telesis7 Consulting

    Saint Louis, MO
    2 days ago
  • The Timberline Group seeks a Software Architect to lead architectural design and development across client projects. You will guide a team through design, coding, and testing, ensuring scalable, robust solutions aligned with business needs. Key focus areas include enforcing...
    Senior

    The Timberline Group

    Saint Louis, MO
    4 days ago
  •  ...the program. As the technical authority, you will monitor systems, troubleshoot anomalies, and develop roadmaps while collaborating with end users, contractors, and Government managers to ensure mission success and engineering excellence. #J-18808-Ljbffr Via Logic LLC
    Senior
    For contractors

    Via Logic LLC

    Saint Louis, MO
    2 days ago
  • BARNES-JEWISH HOSPITAL in St. Louis, MO, invites applications for a Full-Time Senior MRI Advanced Modality Technologist in the Center for Advanced Medicine within the Radiation Oncology Department. The role performs MRI and related modalities, supports lead technicians... 
    Senior
    Full time
    Day shift

    Barnes-Jewish Hospital

    Saint Louis, MO
    1 day ago
  • Volkswagen Group of America seeks a Quality Technical Manager (QTM) to support Volkswagen dealerships by supervising advanced repair diagnostics and ensuring adherence to VW standards. The role focuses on expert guidance to technicians, training, and process improvements... 
    Senior
    Remote job

    Volkswagen Group

    Saint Louis, MO
    1 day ago
  •  ...architecture and modernization strategies while mentoring engineering teams. You will monitor and troubleshoot enterprise-scale systems, manage cloud-based applications for high availability, and collaborate with end users and government managers to ensure mission success.... 
    Senior

    Leidos

    Saint Louis, MO
    2 days ago
  •  ...design, develop, and manage highly customized, risk...  ...leadership and guidance across infrastructure engineering...  ...virtualization, network, and core IT systems such as Active...  ...Head of Technology Operations to develop NISA's...  ...Collaborate with senior leadership and other teams... 
    Senior

    NISA Investment Advisors, LLC

    Saint Louis, MO
    4 days ago
  • An established industry player is looking for a Senior Supply Distribution Technician to oversee the management of medical supplies in a dynamic hospital environment...  ...role involves ensuring efficient supply chain operations, maintaining safety standards, and providing... 
    Senior
    Afternoon shift

    BJC HealthCare

    Saint Louis, MO
    1 day ago
  • A leading technology consulting firm is seeking a Senior Technical Lead to manage technology within complex projects. The role involves mentoring development teams in .Net, guiding code reviews, and ensuring adherence to quality standards. Strong proficiency in the .Net... 
    Senior

    TechDigital Group

    Saint Louis, MO
    1 day ago
  • A leading national engineering and consulting firm seeks a Senior Geotechnical Engineer to support their St. Louis office. This role involves overseeing geotechnical projects, mentoring junior staff, and fostering client relationships. Candidates should possess 12+ years... 
    Senior
    Work at office

    GEI Consultants

    Saint Louis, MO
    1 day ago
  • A leading pharmaceutical company seeks a Senior Technical Support Representative in St. Louis, Missouri. This critical role acts as the liaison between customers and technical teams, providing support and training for both sales teams and customers. Responsibilities include... 
    Senior

    Altana Pharma Deutschland S.L. (Nycomed Germany Holding GmbH...

    Saint Louis, MO
    22 hours ago
  •  ...St. Louis is seeking an experienced professional for a full-time position specializing in Big Data. You'll lead technical teams and manage client interactions, while utilizing your expertise in Hadoop and data warehousing. Ideal candidates will have a Bachelor’s degree... 
    Senior
    Permanent employment
    Full time

    Sonsoft Inc

    Saint Louis, MO
    1 day ago
  • $75.2k - $158.1k

    CACI International Inc is seeking a Network Engineer III in St. Louis, Missouri. This role involves performing research, requirements analysis, design, installation, and troubleshooting of network hardware. Candidates should have a minimum of 5 years of experience in large...
    Senior
    Flexible hours

    CACI International Inc

    Saint Louis, MO
    1 day ago
  • Chameleon Integrated Services is looking for a Senior Network Engineer to support complex LAN/WLAN/WAN issues. This remote role requires hands-on experience with essential networking protocols, tools, and the ability to lead network specialists. The ideal candidate will... 
    Senior
    Remote job

    Chameleon Integrated Services

    Saint Louis, MO
    3 days ago
  • CACI is seeking a Network Engineer III to perform research, requirements analysis, design, installation, documentation, troubleshooting, and sustainment of local and wide-area networks. The role emphasizes system specifications, risk mitigation, QA compliance, and performance...
    Senior
    Local area

    Dormont Manufacturing Co

    Saint Louis, MO
    1 day ago
  • CACI International Inc. is seeking a Network Engineer III in St. Louis, MO, to lead network research, design, and implementation. The role demands strong skills in requirements analysis and technical problem-solving to enhance network performance and security compliance...
    Senior

    CACI International Inc.

    Saint Louis, MO
    1 day ago
  •  ...blend of cloud engineering expertise, operational rigor, and leadership. As a DevOps Team...  ...cloud architecture, lifecycle management, automation strategies, and proactive...  ...environments (Dev & Ops) Responsible for Infrastructure as Code and configuration management... 
    Senior
    Work experience placement
    Relocation
    Relocation package

    General Dynamics Information Technology

    Saint Louis, MO
    10 days ago
  •  ...work on revolutionary federal IT infrastructure, and the opportunity to...  ...have strong experience in operational support and can help take to...  ...has expertise in operations management, quality systems, data operations...  ...from within. Role:  Senior Network Engineer Consultant... 
    Senior
    Immediate start
    Flexible hours

    Chameleon Integrated Services

    Saint Louis, MO
    1 day ago
  • TechDigital Group is seeking an experienced IT Project Manager to lead and deliver technology projects within our IT Services division. The role requires managing scope, timelines, and vendor management while aligning with business goals and IT standards. The candidate... 
    Senior

    TechDigital Group

    Saint Louis, MO
    5 days ago
  •  ...stability, security, and performance of our IT infrastructure across sites nationwide. You will...  ...configure, and troubleshoot network devices, manage security platforms, and provide...  ..., and proactive improvement of network operations. Travel to sites and construction trailers... 
    Senior

    McCarthy Holdings, Inc.

    Saint Louis, MO
    4 days ago
  • SBM Management Services, LP is seeking a Senior Manager for Digital Growth Marketing in St. Louis, MO. This role involves developing and executing digital marketing strategies aimed at customer acquisition and retention through various channels. The ideal candidate will... 
    Senior

    SBM Management Services, LP

    Saint Louis, MO
    4 days ago
  • Washington University in St. Louis is seeking a Senior Technical Project Manager (Hybrid) to own day-to-day and strategic operations of the XNAT open-source project within the Radiology department. You will coordinate a distributed team of engineers and external contributors... 
    Senior

    Washington University

    Saint Louis, MO
    1 day ago
  • Everforth Apex Systems is seeking an Infrastructure Project Manager to lead 15-20 concurrent projects, focusing on scheduling, coordination, and execution...  ...closure, provide executive updates, and collaborate with IT delivery, facilities, and infrastructure teams. A PMP or... 
    Senior

    Apex Systems

    Maryland Heights, MO
    3 days ago
  •  ...consulting through innovation and AI-enabled solutions. This leadership role combines deep actuarial expertise with strategic client management, mentoring teams, and expanding the practice across the insurance ecosystem, while modernizing delivery with analytics and... 
    Senior

    Oliver Wyman

    Saint Louis, MO
    3 days ago
  • Advantage Solutions is looking for a Senior Director of Business Development to lead sales and business development operations. The ideal candidate will have over 8 years of...  ...developing new business opportunities and managing travel requirements, with expectations ranging... 
    Senior
    Remote job
    Full time

    Advantage Solutions

    Saint Louis, MO
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior IT Infrastructure & Operations Manager. Be the first to apply!