Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal AI Engineer

$187.5k - $229.1k

Surescripts

Surescripts serves the nation through simpler, trusted health intelligence sharing, in order to increase patient safety, lower costs and ensure quality care. We deliver insights at critical points of care for better decisions - from streamlining prior authorizations to delivering comprehensive medication histories to facilitating messages between providers.


Job Summary:

The Principal AI Engineer is the most senior individual contributor and technical lead for Surescripts' AI solutions. The role owns the how, the execution, and the by-when for AI initiatives across the enterprise, pairing deep hands-on engineering with the architecture and business judgment to act as a trusted technical partner to product management, engineering, design, and business stakeholders.

The Principal AI Engineer is accountable for technical feasibility, business alignment, and responsible AI practice across Surescripts' platforms. This person designs and delivers AI solutions for both customer-facing products and the internal operations that support Surescripts team members, helping product teams deliver AI that is scalable, reliable, and something they can stand behind.

Responsibilities:

  • Own the technical how and the delivery timeline for AI initiatives, acting as both AI solution architect and principal engineer.
  • Architect and build scalable, interoperable, responsible AI solutions, including generative AI, RAG, agentic AI, and predictive models, and guide their deployment into production.
  • Serve as a trusted technical partner across groups and projects, providing solution architecture and weighing options on technical feasibility, effort, and performance targets.
  • Translate business and customer needs into technical requirements, and frame technical options and trade-offs so leaders and stakeholders can make informed decisions that line up with business outcomes.
  • Lead the technical evaluation of new AI technologies and vendors, judging architectural fit, capability, and integration approach.
  • Prototype and validate advanced AI approaches to prove out architectural direction and de-risk initiatives before teams commit to them.
  • Run architecture and design reviews across teams, surfacing key trade-offs and keeping decisions transparent and sound.
  • Set and evolve AI engineering standards, including model integration, data architecture, LLMOps, AgentOps, and AI development best practices from frameworks such as NIST RMF, CHAI, OWASP, etc.
  • Serve as a lead mentor regarding enterprise AI Trust & Safety best practices from: auto-inherited controls and guardrails based on AI solution type and risk level, to automated evals and testing in CI/CD, to operational monitoring and drift detection, to issue and incident response, to data-driven continuous improvement of AI solutions. Ensure the necessary technical components are designed-in and operationally effective to meet anti-bias, accuracy, transparency, explainability, safety, and regulatory compliance.
  • Mentor engineers and raise the technical bar, building a team culture of collaboration and steady learning.
  • Keep current with new AI technologies and frameworks and turn trends into practical strategies for the teams you support.
Qualifications:

Basic Requirements:
  • Bachelor's degree in Engineering, Computer Science, or a related field, or equivalent experience
  • 8+ years of related, progressive software, data, or AI/ML engineering experience
  • 4+ years in a lead and/or senior engineering role with a focus on leading and mentoring engineers to deliver software products
  • 3+ years of hands-on machine learning / AI engineering experience
  • Proven experience architecting and delivering solutions across multiple technical domains, such as APIs and microservices, systems integration and event-driven architectures, AI/ML engineering, data engineering and analytics, and core software engineering (cloud-native applications, distributed systems)
Preferred Qualifications:
  • 3+ years developing and implementing AI solutions in a healthcare setting
  • Experience designing production AI/ML applications using big-data technologies, cloud platforms (AWS, Azure, GCP), and data pipeline orchestration
  • Experience working in the SVPG framework or a substantially similar outcomes-driven product operating model

Surescripts embraces flexibility through its Flexible Hybrid Work model for most positions. This model allows employees to work virtually while still utilizing our offices as collaboration centers. With alignment and agreement from your leadership, you can come and go from the office as needed.

To be considered for employment, applicants must have a valid U.S. work authorization allowing work without restrictions with Surecripts in the U.S. At this time, we are unable to provide support or provide sponsorship for immigration benefits such as work visas. Additionally, we do not participate in academic training programs or work-study programs through an academic institution that require employer endorsement of F-1/CPT or F-1/STEM.

Why Wait? Apply Now


We're a midsize company. This means you're not just another employee ID number. Here, you can build real relationships and feel supported by truly awesome people with diverse backgrounds and talents in an innovative and collaborative work culture. We strive to create an environment where you can be yourself, share your ideas and work your way. We offer opportunities for employee development, as well as competitive compensation packages and extensive benefits.


At Surescripts, base pay is one part of our Total Rewards Package (which may also include bonus, benefits etc.) and is determined within a range. The base pay range for this position is $187,500 - $229,100 per year. Your base pay may vary within or outside of this range depending on a number of factors, including (but not limited to) your qualifications, skills, experience, and location.

Benefits include, but are not limited to, comprehensive healthcare (including infertility coverage), generous paid time off including paid childbirth and parental leave and mental health days, pet insurance, and 401(k) with company match and immediate vesting. To learn more, review the Keep You and Yours Healthy, Balancing Work and Life, and Where Talent Takes Shape links under the Better Benefits. Better Work. Better Life section of our careers site.

Physical and Mental Requirements

While performing duties of this job, an employee may be required to perform any, or all of the following: attend meetings in and out of the office, travel, communicate effectively (both orally and in writing), and be able to effectively use computers and other electronic and standard office equipment with, or without, a reasonable accommodation. Additionally, this job requires certain mental demands, including the ability to use judgement, withstand moderate amounts of stress and maintain attention to detail with, or without, a reasonable accommodation.

Surescripts is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate on the basis of race, color, religion, age, national origin, ancestry, disability, medical condition, marital status, pregnancy, genetic information, gender, sexual orientation, parental status, gender identity, gender expression, veteran status, or any other status protected under federal, state, or local law.

#LI-REMOTE
Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Principal AI Engineer in Minneapolis, MN vacancy
  •  ...We are looking for a passionate and hands-on AI Builder to join our AI Engineering team. This role is ideal for someone with 1–2 years of experience who enjoys building AI-powered applications, experimenting with the latest Large Language Models (LLMs), and developing... 
    Suggested
    Full time

    Brillio

    Minneapolis, MN
    9 hours ago
  • $114.5k - $171.8k

     ...SUMMARY  Mortenson is currently seeking a Senior AI Ops Engineer - ITS that will be responsible for providing advanced support in all activities related to the development of solutions within our applications architecture; working with other groups to design, document... 
    Suggested
    H1b
    Work at office

    Mortenson

    Minneapolis, MN
    2 days ago
  • $171.9k - $300.8k

     ...closing in March 2026. The combination brings together Veza's AI-native Access Graph with ServiceNow's AI Control Tower and agentic...  ...applications, data, cloud environments, and AI agents. For engineers joining Veza today, this means the scale and resources of an enterprise... 
    Suggested
    Full time
    Work experience placement
    Work at office
    Remote work
    Flexible hours

    Servicenow

    Minneapolis, MN
    9 hours ago
  •  ...We are: A forward-thinking services company at the forefront of AI-native innovation. We partner with enterprise clients to create next-generation, agent-powered workflows engineered to scale in real-world settings. Our engineers embed deeply with customers, moving... 
    Suggested
    Work experience placement
    Live in
    Work at office
    Local area

    Accenture

    Minneapolis, MN
    3 days ago
  • $73.5k - $212.28k

     ...At PwC, our people in data and analytics engineering focus on leveraging advanced technologies and techniques to design and develop robust...  ...Engineering team you will lead the development of innovative AI solutions that drive remarkable client outcomes. As a Manager... 
    Suggested
    H1b

    PwC

    Minneapolis, MN
    1 day ago
  • $161.3k - $201.9k

     ...processes and bring data to life. The Principal position will balance business solution architecture...  ...experience as a seasoned middleware engineer. • Minimum of seven (7) years of...  ...time We may use artificial intelligence (AI) tools to support parts of the hiring... 
    Full time
    Part time
    Work at office
    Local area
    Visa sponsorship

    Allegiant Travel

    Minneapolis, MN
    9 hours ago
  •  ...acquisition, and creative development firm that addresses clients' most pressing needs and challenges. We are currently looking for an AI Engineer (Databricks Background). Need: AI Engineer (Databricks Background) Location - Remote Duration Long term... 
    Remote work

    Momento USA

    Minneapolis, MN
    2 days ago
  • AI Engineer- 1-2 Years exp) Minneapolis, MN- 100% onsite Full Time Job Description Programming & Software Engineering: Expertise in Python (and optionally Java, JavaScript, or C#), unit testing, and version control (Git). AI/ML Knowledge: Solid grasp of machine learning... 
    Full time

    Siri InfoSolutions Inc

    Minneapolis, MN
    2 days ago
  • About Blank Metal Blank Metal is an AI-native engineering company that partners with enterprises to deliver production AI fast. We blend strategic insight with hands-on execution, shipping high-impact systems that turn AI initiatives into measurable business results. We... 

    Blank Metal

    Minneapolis, MN
    6 days ago
  • $175k - $205.9k

     ...Are you ready to make an impact?West Monroe is searching for a Principal AI Software Engineer, to join our team in our Technology & Experience (TechEx) practice. You will partner with our clients and other West Monroe team members on transformational AI projects. On client... 
    Local area
    Immediate start
    Flexible hours

    West Monroe Partners

    Minneapolis, MN
    a month ago
  • $117.6k - $206k

     ...future.SummaryIn this role, you will lead the execution, operationalization, scaling, and continuous improvement of enterprise AI engineering and delivery initiatives across Vizient. You will implement scalable AI engineering practices, AI delivery operating models, AIOps... 
    Full time
    For contractors

    Vizient

    Edina, MN
    a month ago
  • $100k - $170k

     ...of transforming Financial Advisor productivity through agentic AI workflows—bridging business problems with intelligent automation...  ...interoperate within a governed ecosystem. This is not a pure engineering role—it's a product-minded builder role that shapes, validates,... 
    Full time
    Flexible hours

    Royal Bank of Canada

    Minneapolis, MN
    14 days ago
  • $18 - $50 per hour

     ...university graduation and completion of the program Position Overview: Siemens Digital Industries Software is seeking an AI & Engineering Data Intern to support emerging Artificial Intelligence and Digital Thread initiatives within the Capital PreSales... 
    Remote job
    Hourly pay
    Full time
    Internship
    Local area

    Siemens

    Minneapolis, MN
    3 days ago
  • AI Engineer Opportunity Plymouth, MN (On-Site) 40 hrs/week | Start: Immediate The SaaSpocalypse is real. Salesforce, Workday, ServiceNow, and Epic are all feeling it. The per-seat, legacy-workflow model is being dismantled in real time and the companies that built their... 
    Immediate start

    EWINGS INC.

    Minneapolis, MN
    6 days ago
  • $215k - $275k

     ...and software products with clients who are ready to accelerate AI-enabled digital product development. We imagine how things can...  ...quality, resilience, and purpose. By blending design, product engineering, analytics, and automation, we build the AI-enabled custom software... 
    Temporary work
    Local area

    Slalom

    Minneapolis, MN
    1 day ago
  • $125k - $150k

     ...Description The Senior AI/ML Engineer will play a crucial role in the AI Center of Excellence (CoE), supporting cross-functional teams across the organization. This position will focus on designing, developing, and developing machine learning (ML), artificial intelligence... 
    Permanent employment
    Remote work
    Minneapolis, MN
    3 days ago
  •  ...similar). 2 years of hands-on experience in developing and deploying AI agents and machine learning models. Demonstrate deep expertise...  ...in a startup-style environment. Work closely with senior engineers and researchers, learning best practices and contributing to production... 

    Omni Inclusive

    Minneapolis, MN
    6 days ago
  • $65 per hour

    About the job AI/ML Engineer AI/ML Engineer Location: Minneapolis, MN Job Type (C2C): C2C Job Mode: Remote Pay Rate: $65/hr Industry: Information Technology / AI & CRM Integration End Date: 01-Dec-2026 Job Description We are seeking an AI/ML Engineer with strong expertise... 
    Remote work

    Simarn Solutions

    Minneapolis, MN
    6 days ago
  •  ...to inspire healthy living through WOW flavor experiences.   Our corporate office in Livonia Michigan is currently seeking an AI Engineer to join our team. The AI Engineer is responsible for building, deploying, and maintaining AI-powered applications and integrations... 
    Full time
    Work at office

    Sunset

    Plymouth, MN
    9 hours ago
  • $148.9k - $255.3k

     ...together.UnitedHealthcare is accelerating its next-generation AI transformation through Claims AI 10.0 and Enterprise Agentic AI...  ...initiatives. We are seeking a highly experienced Senior Manager AI/ML Engineering to lead multiple AI engineering teams responsible for building... 
    Minimum wage
    Full time
    Work experience placement
    Work at office
    Local area
    Remote work

    UnitedHealth Group

    Minnetonka, MN
    a month ago
  • $164.6k - $282.2k

     ...work better for everyone. From advanced data analytics and AI to cybersecurity, we use innovative approaches to solve some...  ...start Caring. Connecting. Growing together.We are looking for a Principal AI/ML Engineer to lead the architecture, design, and end-to-end development... 
    Minimum wage
    Full time
    Work experience placement
    Work at office
    Local area
    Remote work

    UnitedHealth Group

    Plymouth, MN
    2 days ago
  • $200.4k - $343.5k

     ...system work better for everyone. From advanced data analytics and AI to cybersecurity, we use innovative approaches to solve some of...  .... Connecting. Growing together.The Vice President of AI/ML Engineering for Medicare & Retirement (M&R) is responsible for driving AI-first... 
    Minimum wage
    Full time
    Work experience placement
    Work at office
    Local area
    Remote work

    UnitedHealth Group

    Minnetonka, MN
    a month ago
  • $124.36k - $146.3k

    Senior Engineer (Generative AI) At U.S. Bank, we're on a journey to do our best. Helping the customers and businesses we serve to make better and smarter financial decisions and enabling the communities we support to grow and succeed. We believe it takes all of us to bring... 
    Temporary work
    Work experience placement
    3 days per week

    U.S. Bancorp

    Minneapolis, MN
    2 days ago
  • $78.3k

     ...and career. Here, you’ll be supported in progressing – whatever your ambitions.   Position Summary As a forward deployed AI Engineer, you will serve as an embedded technical expert supporting the development, deployment, and sustainment of AI-enabled solutions across... 
    Hourly pay
    Full time
    Contract work
    Shift work

    Boston Scientific

    Arden Hills, MN
    9 hours ago
  • $15k

     ...more about our company culture and impact in our latest annual report. Summary/Function: We are seeking a Mid-Level AI and Automation Engineer to develop next-generation AI capabilities within our Microsoft-based environment. This role will focus on building... 
    Work experience placement
    Local area

    D.A. Davidson

    Minneapolis, MN
    27 days ago
  •  ...AI Software Engineer Anywhere Type: Contract-to-Hire Category: Engineer Industry: Financial Services Workplace Type: Remote Standard Hours: Open Reference ID: JN -092026-108475 Date Posted: 09/01/2026 Shortcut: Description Recommended... 
    Hourly pay
    Contract work
    Local area
    Remote work

    Eliassen Group

    Saint Paul, MN
    1 day ago
  •  ...like you that way.We improve the way employers offer health benefits and provide employees coverage they can use. The Staff AI Test Automation Engineer at Gravie will take hands-on ownership of our AI-driven test automation systems across our product portals. The... 
    Contract work
    Work experience placement
    Local area
    Flexible hours

    Gravie

    Minneapolis, MN
    7 days ago
  •  ...Senior Life Sciences Knowledge Engineer Company: Norstella Location: Remote, United States Date Posted: Jul 24, 2026 Employment...  ...intersection of deep scientific domain expertise and applied AI development. This role will be embedded within a group of life science... 
    Full time
    Temporary work
    Work at office
    Local area
    Remote work
    Flexible hours
    Shift work

    Norstella

    Saint Paul, MN
    2 days ago
  •  ...degree or Master’s degree or equivalent experience in Electrical Engineering, Electronics, or Computer Architecture.Minimum of 15 years of...  ...from candidates as consideration for their employment with Micron.AI alert: Candidates are encouraged to use AI tools to enhance... 
    Full time
    Local area
    Immediate start

    Micron

    Minneapolis, MN
    a month ago
  •  ...Principal Engineer, Agentic AI At Teradata, we believe that people thrive when empowered with better information. Teradata Autonomous Knowledge Platform activates enterprise intelligence by unifying data, knowledge and business context to achieve tangible outcomes.... 
    Flexible hours

    Minnesota Jobs

    Saint Paul, MN
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal AI Engineer. Be the first to apply!