Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Applied Scientist

$142.8k - $274.8k

Microsoft Corporation

Overview

We are looking for a Principal Applied Scientist to help define, evaluate, and build the next generation of AI-powered product experiences. This role requires a leader who combines deep applied science expertise in LLMs, evaluation systems, AI, MLOps, experimentation, and software engineering with strong product judgment and a proven ability to ship high-quality AI solutions.

You will play a critical role in shaping how AI capabilities are developed, measured, improved, and brought into production. The ideal candidate has experience building AI-based products end to end, defining what success looks like for customers and the business, and creating rigorous evaluation frameworks that guide fast, high-confidence product iteration.

Microsoft’s mission is to empower every person and every organization on the planet to achieve more. As employees we come together with a growth mindset, innovate to empower others, and collaborate to realize our shared goals. Each day we build on our values of respect, integrity, and accountability to create a culture of inclusion where everyone can thrive at work and beyond.

Responsibilities

  • Lead applied science strategy for AI-powered product areas, from ambiguous opportunity identification through experimentation, launch, and continuous improvement.

  • Define what success looks like for AI product experiences , including customer value, quality thresholds, reliability, safety, engagement, and measurable business impact.

  • Design and operationalize LLM evaluation frameworks across the product development lifecycle , including early prototyping, model/prompt iteration, feature development, pre-launch validation, launch readiness, and post-launch monitoring.

  • Build evaluation methodologies for LLM-based, agentic, retrieval-augmented, and multimodal AI systems , including text, image, document, audio, video, and interaction-based experiences where applicable.

  • Develop robust offline experimentation and evaluation pipelines to compare models, prompts, system designs, retrieval strategies, grounding quality, tool use, and end-to-end product behavior.

  • Partner closely with engineering and PM leadership to align science priorities with product strategy, roadmap decisions, customer needs, and execution plans.

  • Work with software engineering teams to productionize AI systems with strong attention to reliability, scalability, latency, observability, maintainability, and MLOps best practices.

  • Drive fast iteration cycles by forming hypotheses, defining metrics, running experiments, interpreting results, and recommending clear product or technical actions.

  • Establish quality bars and decision-making frameworks for AI launches, including evaluation scorecards, regression testing, guardrail metrics, and responsible AI considerations.

  • Mentor scientists and engineers, raise the technical bar, and influence cross-team best practices for AI development, experimentation, and evaluation.

  • Communicate findings, tradeoffs, risks, and recommendations clearly to technical and non-technical stakeholders.

Qualifications

Required Qualifications:

  • Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 4+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 3+ years related experience (e.g., statistics, predictive analytics, research)

  • OR equivalent experience.

Other Requirements:

  • Ability to meet Microsoft, customer and/or government security screening requirements are required for this role. These requirements include but are not limited to the following specialized security screenings:

  • Microsoft Cloud Background Check: This position will be required to pass the Microsoft Cloud background check upon hire/transfer and every two years thereafter.

Preferred Qualifications:

  • Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 13+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 10+ years related experience (e.g., statistics, predictive analytics, research)

  • OR equivalent experience.

  • 5+ years experience creating publications (e.g., patents, libraries, peer-reviewed academic papers).

  • 2+ years experience presenting at conferences or other events in the outside research/industry community as an invited speaker.

  • 5+ years experience conducting research as part of a research program (in academic or industry settings).

  • 3+ years experience developing and deploying live production systems, as part of a product team.

  • 3+ years experience developing and deploying products or systems at multiple points in the product cycle from ideation to shipping.

  • Significant experience building, evaluating, and shipping AI/ML-powered products or services .

  • Hands-on experience with large language models , including prompt engineering, RAG, agents, tool use, model comparison, failure analysis, and evaluation-driven iteration.

  • Deep understanding of LLM evaluation throughout the development lifecycle , including dataset creation, annotation strategies, automated and human evaluation, benchmark design, regression testing, launch criteria, and production monitoring.

  • Experience designing offline experiments and interpreting results to inform model, system, and product decisions.

  • Experience evaluating multimodal AI systems or AI experiences involving multiple input/output modalities.

  • Solid understanding of product success metrics and ability to translate customer/business goals into measurable scientific and technical objectives.

  • Solid software engineering skills and experience collaborating with engineers to build production-quality AI systems.

  • Experience with MLOps , experimentation infrastructure, telemetry, monitoring, data pipelines, and continuous improvement loops.

  • Demonstrated ability to work closely with PM and engineering leadership to influence product direction and drive execution in ambiguous environments.

  • Excellent communication, collaboration, and technical leadership skills.

  • Experience with agentic workflows, enterprise AI, productivity tools, developer tools, or customer-facing AI products.

  • Experience with responsible AI, safety evaluations, red teaming, hallucination measurement, grounding quality, bias/fairness assessment, privacy, or compliance-related AI evaluation.

  • Experience creating reusable evaluation platforms, experimentation frameworks, model scorecards, or AI quality dashboards.

  • Experience combining offline evaluation, online experimentation, telemetry, and qualitative customer feedback into a unified product decision framework.

  • Track record of influencing senior stakeholders through applied science insights and measurable customer or business impact.

  • Publications, patents, open-source contributions, or recognized technical leadership in AI/ML are a plus.

#AI #LLM #Evals #AppliedScience

Applied Sciences IC5 - The typical base pay range for this role across the U.S. is USD $142,800 - $274,800 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.

Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here:

This position will be open for a minimum of 5 days, with applications accepted on an ongoing basis until the position is filled.

Microsoft is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, color, family or medical care leave, gender identity or expression, genetic information, immigration status, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran or military status, race, ethnicity, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable local laws, regulations and ordinances. If you need assistance with religious accommodations and/or a reasonable accommodation due to a disability during the application process, read more about requesting accommodations. (

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Principal Applied Scientist in Redmond, WA vacancy
  • $198.9k - $269k

     ...As a Principal Applied Scientist, you are a trusted part of the technical leadership. You bring business and industry context to science and technology decisions. You set the standard for scientific excellence and make decisions that affect the way we build and integrate... 
    Principal
    Flexible hours

    Amazon

    Bellevue, WA
    2 days ago
  •  ...Principal Applied Scientist The people at UiPath believe in the transformative power of automation to change how the world works. We're committed to creating category-leading enterprise software that unleashes that power. To make that happen, we need people who are... 
    Principal
    Work at office
    Immediate start
    Remote work

    UiPath

    Bellevue, WA
    4 days ago
  • $142.8k - $274.8k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...advertiser strategies and auction mechanisms. In our team, applied scientists work together and utilize all sorts of platforms, techniques,... 
    Principal
    Ongoing contract
    Work at office
    Local area

    Microsoft

    Redmond, WA
    5 days ago
  • $142.8k - $274.8k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...GitHub Copilot and Azure OpenAI. We are looking for a Principal Applied Scientist to join our team!Microsoft’s mission is to empower every person... 
    Principal
    Ongoing contract
    Work at office
    Local area
    Shift work
    3 days per week

    Microsoft

    Redmond, WA
    6 days ago
  • $142.8k - $274.8k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...on the planetCollaborate closely with backend engineers, data scientists, site reliability engineers (SREs), and product managers to gather... 
    Principal
    Ongoing contract
    Local area
    3 days per week

    Microsoft

    Redmond, WA
    7 days ago
  • $142.8k - $274.8k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...Copilot, Bing, Edge, Windows, and Xbox. We are seeking a Principal Applied Scientist to define and develop the next generation of intelligent,... 
    Principal
    Ongoing contract
    Work at office
    Local area

    Microsoft

    Redmond, WA
    7 days ago
  • $142.8k - $274.8k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...streamline workflows across organizational tools. As a Principal Applied Scientist, you will define scientific vision and lead the development... 
    Principal
    Ongoing contract
    Work at office
    Local area
    Immediate start

    Microsoft

    Redmond, WA
    7 days ago
  • $130k - $160k

     ...contributions to the company's success.   We are seeking a Principal Scientist to provide technical leadership for the development of...  ...SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.... 
    Principal
    Full time

    Systimmune

    Redmond, WA
    more than 2 months ago
  • $150k - $300k

     ...catastrophic situations. Job Description J.S. Held is seeking a Principal Epidemiologist to join our Health Sciences practice. This role...  ...in a consulting environment Methods & Analytics Apply advanced epidemiologic methodologies, including: Cohort and... 
    Principal
    Remote work
    Flexible hours

    J.S. Held LLC

    Redmond, WA
    4 days ago
  •  ...believe the next generation of software won't simply automate tasks—it will reason, plan, adapt, and act autonomously.As a Principal Applied Scientist, you'll help invent that future.You will lead the research and development of frontier AI systems that combine foundation... 
    Principal
    Work at office
    Immediate start
    Remote work

    UiPath

    Bellevue, WA
    4 days ago
  • $198.9k - $269k

    The Principal Applied Scientist will own the science mission for building next-generation proactive and autonomous agentic experiences across Alexa AI's Personalization, Autonomy and Proactive Intelligence organization. You will technically lead a team of applied scientists... 
    Principal
    Worldwide
    Flexible hours

    Amazon

    Bellevue, WA
    5 days ago
  • $142.8k - $274.8k

     ...ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Research...  ...and multi-disciplinary group of scientists, researchers and engineers with passion...  ...seeking entrepreneurial and creative Principal Applied Researcher to lead groundbreaking... 
    Principal
    Ongoing contract
    Local area
    3 days per week

    Microsoft

    Redmond, WA
    5 days ago
  • $192k - $304.75k

     ...accelerated computing. We're looking for a passionate AI research scientist with deep quantum computing expertise to path-find the future...  ..., and our goal is to accelerate the entire ecosystem. As a Sr. Applied Research Scientist in Quantum Computing, you will architect and... 

    NVIDIA Gruppe

    Redmond, WA
    1 day ago
  • $192k - $304.75k

     ...with deep quantum computing domain expertise to path-find the future. As a Senior Quantum Error Correction Research Scientist for Quantum Computing Applied Research, you'll focus on technical pathfinding, helping to develop innovative technologies that advance the state... 
    Full time

    Nvidia

    Redmond, WA
    5 days ago
  • $192k - $304.75k

     ...approach to accelerated computing. We're looking for a passionate scientist at the intersection of quantum device physics and advanced...  ...help accelerate the entire quantum ecosystem. As a Sr. Quantum Applied Research Scientist, you will help design and build high-fidelity... 
    Full time
    Remote work

    Nvidia

    Redmond, WA
    5 days ago
  • $192k - $304.75k

     ...approach to accelerated computing. We're looking for a passionate scientist at the intersection of quantum device physics, quantum...  ...help accelerate the entire quantum ecosystem. As a Sr. Quantum Applied Research Scientist, you will help design and build real-time models... 
    Full time
    Remote work

    Nvidia

    Redmond, WA
    5 days ago
  • $102.1k - $202.2k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...team within this division is looking for an experienced Applied Scientist II and a Senior Applied Scientist with a proven track record to... 
    Ongoing contract
    Local area
    3 days per week

    Microsoft

    Redmond, WA
    6 days ago
  • $167.1k - $226.1k

     ...agencies, Amazon Leo will serve people and organizations operating in locations without reliable connectivity.The RoleAs a Senior Applied Scientist in Project Leo, you’ll be leading us in making critical and time sensitive decisions that impact customers. You’ll use your... 
    Permanent employment
    Flexible hours

    Amazon

    Redmond, WA
    4 days ago
  • $119.8k - $234.7k

     ...yearEmployment type: Full-TimeWork site: 4 days / week in-officeRole type: Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany: MicrosoftOverviewMicrosoft Monetization is building the next generation of AI-... 
    Ongoing contract
    Work experience placement
    Work at office
    Local area

    Microsoft

    Redmond, WA
    3 days ago
  • $119.8k - $234.7k

     ...Individual ContributorTravel: Less than 25%Profession: Research, Applied, & Data SciencesDiscipline: Applied SciencesCompany:...  ...delayed conversions and shifting marketplace dynamics.Engineers and scientists on the team work at the intersection of deep learning, large-scale... 
    Ongoing contract
    Work at office
    Local area
    Shift work

    Microsoft

    Redmond, WA
    6 days ago
  • $169.59k - $206.23k

     ...tumor targets.Position OverviewWe are seeking an experienced Principal Scientist, Chemical Development to join our dynamic team to help advance...  ...targeted cancer therapies. The successful candidate will apply their expertise in small molecule process development and manufacturing... 
    Principal
    Afternoon shift

    Immunome

    Bothell, WA
    3 days ago
  • $90k - $130k

     ...contributions to the company's success. We are seeking an innovative Scientist or Senior Scientist with industry experience in protein...  ...SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.... 
    Full time
    Work at office

    Systimmune

    Redmond, WA
    more than 2 months ago
  • $90k - $140k

     ...significant contributions to the company's success.   The Senior Scientist in the Cell Science Department is responsible for the...  ...SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.... 
    Full time
    Shift work
    Weekend work

    Systimmune

    Redmond, WA
    more than 2 months ago
  • $86.9k - $122.7k

     ...case narratives and electronic data deliverables, evaluating method performance and QA/QC results, and documenting data usability. Apply knowledge of analytical chemistry, environmental sampling design, laboratory methods, data validation principles, data quality objectives... 
    For subcontractor
    Local area

    WSP

    Redmond, WA
    4 days ago
  • $90k - $140k

     ...significant contributions to the company's success. This Senior Scientist role is in the research and development division. The ideal...  ...agentic AI-based system development are highly encouraged to apply.   This role is full-time onsite at our Redmond, WA location... 
    Full time
    Work at office

    Systimmune

    Redmond, WA
    a month ago
  • $84k - $100k

     ...Children is an amazing place to grow your career as a Research Scientist. We're a social enterprise dedicated to advancing the well-being...  ...Methods, or related field required. ~ Experience conducting applied research to support product development, innovation, program design... 
    Work at office
    Remote work
    Flexible hours

    Committee for Children

    Redmond, WA
    1 day ago
  • $192.2k - $260k

     ...obstacles to varying weather and lighting conditions - all while ensuring every package arrives safely as per our promise.As an Applied Scientist on our Last Mile Technology team, you'll be at the forefront of developing computer vision and perception systems that enable... 
    Local area
    Flexible hours

    Amazon

    Bellevue, WA
    7 days ago
  • $167.1k - $226.1k

    Alexa AI is looking for a Senior Applied Scientist to build Alexa+, Amazon's LLM-powered conversational assistant. You will work on key initiatives spanning large language model fine-tuning, alignment, agentic reasoning, and evaluation — directly shaping the experience... 
    Worldwide
    Flexible hours

    Amazon

    Bellevue, WA
    4 days ago
  • $167.1k - $226.1k

     ...actionable intelligence, and power autonomous agents that learn from every customer interaction. We are looking for a Senior Applied Scientist to lead the development of generative AI applications that change how finance teams work, tackling problems at the intersection... 
    Contract work
    Flexible hours

    Amazon

    Bellevue, WA
    7 days ago
  • $192.2k - $260k

     ...of the movies and into our homes. If you're excited about this robotics revolution, come join Amazon's Fauna Robotics. As an Applied Scientist in this org, you'll push the state-of-the-art techniques in Robotics. You'll drive technical excellence in areas such as perception... 
    Local area
    Flexible hours

    Amazon

    Bellevue, WA
    7 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Applied Scientist. Be the first to apply!