Post-Doctoral Research Fellow - Chromatin Biology

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. The Arimura Lab in the Basic Sciences Division at Fred Hutch is seeking a highly motivated Postdoctoral Fellow. The ideal candidate will have a strong interest in chromatin biology and prior research experience in the field. Our lab investigates how chromatin-associated complexes alter their functions in a context-dependent manner, including during the cell cycle, cellular differentiation, and the DNA damage response. To uncover the structural basis of these regulatory mechanisms, we use cryogenic electron microscopy (cryo-EM) to analyze native chromatin-associated complexes isolated from human cells or assembled in Xenopus (frog) egg extracts. By continuing to develop innovative approaches that enable structural determination of native chromatin-associated complexes, we aim to elucidate the structural foundations of key biological events on eukaryotic chromosomes. The Arimura Lab provides a supportive and collaborative environment that places a strong emphasis on individualized mentoring. From the outset, we will work with you to foster your growth as an independent scientist. Together, we will identify your research interests and develop plans to achieve your scientific and professional goals. Fred Hutch and the Basic Sciences Division additionally offer extensive career development resources, comprehensive benefits, and competitive salaries for postdoctoral fellows. Cover letters are highly desired from applicants. Please include a summary of your past research experience and accomplishments, a description of the research you hope to pursue as a future independent investigator (PI), and how experience in our lab will help you achieve those goals. Responsibilities Conduct research aimed at elucidating the structural basis of biological events on eukaryotic chromosomes. Present research findings at group meetings and scientific conferences. Prepare manuscripts for publication. Provide mentorship to graduate students and research technicians. Contribute positively to the lab’s community, culture, and intellectual environment. Other Expectations Treat all members of the lab and the broader Fred Hutch community with respect. Apply for postdoctoral fellowships and/or career development awards. Work collaboratively within the Arimura Lab as well as with other groups at Fred Hutch and external collaborators. MINIMUM QUALIFICATIONS Ph.D. degree in a relevant field (including those expecting to complete their degree soon). A strong publication record. PREFERRED QUALIFICATIONS Background in chromatin biology. Background in Genomics. At least one first-author research article or preprint in chromatin biology (structural biology experience is not required). Cover letters are highly desired from applicants. Please include a summary of your past research experience and accomplishments, a description of the research you hope to pursue as a future independent investigator (PI), and how experience in our lab will help you achieve those goals. The annual base salary range for this position is from $80,172 to $95,014, and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance. This position is not eligible for H-1B sponsorship at this time. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks). #J-18808-Ljbffr