Bioinformatics Scientist

Job Description

Job Description

Position Title: Bioinformatics Scientist

Classification: Exempt

Reports To: Manager of Bioinformatics

About Active Motif

Active Motif is a global leader in developing and delivering innovative tools and services for epigenetics and gene regulation research. We are committed to providing high-quality products, cutting-edge technologies, and exceptional scientific support to the life science, clinical, and pharmaceutical research communities. Our comprehensive portfolio of epigenetics assays, sequencing services, and analytical solutions empowers researchers to investigate chromatin biology, gene regulation, and disease mechanisms with confidence.

Position Summary

The Bioinformatician is responsible for analyzing and interpreting large-scale genomics and epigenomics datasets generated from next-generation sequencing (NGS) experiments. This role involves developing and maintaining analytical pipelines, applying advanced statistical and computational methods, and collaborating with internal scientists and external customers to deliver high-quality biological insights.

The ideal candidate will have strong expertise in epigenetics and transcriptomics data analysis, experience with high-throughput sequencing technologies, and proficiency in bioinformatics software development and workflow automation. This position requires both independent problem-solving skills and effective collaboration within multidisciplinary teams.

Key Responsibilities

• Analyze and interpret large-scale genomics and epigenomics datasets using advanced computational methods e.g., ML/DL, statistical model.
• Perform standardized and custom bioinformatics analyses for external customers and internal research teams.
• Develop, optimize, and maintain bioinformatics pipelines and analytical workflows for NGS assays.
• Support assay development and novel analytical method implementation for transcriptomic and epigenetic datasets.
• Collaborate with cross-functional teams to design experiments, interpret results, and provide analytical recommendations.
• Communicate findings through reports, presentations, and customer interactions
• Maintain and improve pipelines for assays including ChIP-seq, CUT&RUN/CUT&Tag, ATAC-seq, RNA-seq, Hi-C, DNA methylation, and single-cell sequencing technologies
• Stay current with emerging bioinformatics methods, software, and best practices

Qualifications

Required

• MS or PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, Statistics, or related field.
• Minimum 2 years of post-graduate academic or industry experience in bioinformatics or computational biology.
• Strong knowledge of epigenetics, gene regulation, and next-generation sequencing technologies.
• Experience analyzing large-scale genomics, transcriptomics, or epigenomics datasets.
• Proficiency in R and/or Python, Linux/bash scripting, and Git version control.
• Strong statistical, analytical, and data visualization skills.
• Excellent written and verbal communication skills with ability to collaborate across multidisciplinary teams.

Preferred

• Experience with workflow and pipeline development using Nextflow or similar framework.
• Familiarity with Docker, Conda, cloud, or HPC environments.
• Experience with machine learning, statistical modeling, or multi-omics data integration.
• Experience with single-cell sequencing data analysis.
• Ability to communicate complex analytical findings to both technical and non-technical audiences.

What Active Motif can offer?

• Health Insurance: Medical, Dental, and Vision (offering no-cost employee premium plans; and 50% subsidized premiums for dependents)
• Life Insurance, Short- and Long-term Disability Insurance Employer-Paid
• 401(k) after ninety (90) days of employment
• Paid Time Off (PTO): 120 hours on an annual incremental schedule
• Ten (10) paid Major Holidays, and year-end paid Holiday time off
• Free Electric Vehicle Charging Station
• Salary Range: $95,000 - $125,000 Annually

* The salary of the final candidate selected for this role will be set based on a variety of factors, including but not limited to, experience, education, specialization, skills, abilities, and training. The salary range represents Active Motif's good faith and reasonable estimate of the possible compensation at the time of the posting. Certain positions may be eligible for additional compensation such as commission, bonus, and stock options. All benefits are subject to eligibility requirements.