Postdoc fellow - CRISPR screens in hematopoietic stem cells to study replication fitness
Perelman School of Medicine
University of Pennsylvania: Postdoctoral Positions: Perelman School of Medicine Postdoctoral Location University of Pennsylvania, Perelman School of Medicine Open Date Jul 31, 2026 Description A postdoctoral fellow position is available at the University of Pennsylvania School of Medicine and the Children's Hospital of Philadelphia to perform state-of-the-art CRISPR/Cas9 screens to identify novel therapeutic targets for treating hematopoietic stem cell diseases. Dr. Tong’s laboratory studies cytokine receptor signaling in replication stress , DNA repair , and ubiquitin signaling in hematopoietic stem cells , bone marrow failure , and leukemia . Hematopoietic stem cells give rise to all circulating blood cells throughout life. Maintenance of stem cell self-renewal, proliferation, and differentiation is regulated by complex signaling pathways. Aberrant regulation leads to bone marrow failure or leukemia. Genome integrity plays a critical role in blood development and the prevention of leukemia and ageing. This postdoctoral fellow position will focus on studying the mechanisms that safeguard the genome during DNA replication and investigating how failures in these processes impact hematopoietic stem cell function, which leads to bone marrow failure and/or leukemia. CRISPR screens with our expert collaborators will delineate a new understanding of stem cell fitness upon replication stress and point to potentially druggable pathways for intervention in the treatment of diseases with stem cell dysregulation. Our recent publications include: Cell Stem Cell , 28(7):1275-1290, 2021; Journal of Clinical Investigation 136(1): e191713, 2026; Blood 138(22):2244-2255, 2021; Blood 133(14): 1560-1571, Apr 2019. Nature communications 9(1): 3915, Sep 2018; Genes & development 31(10): 1007-1023, May 2017; You can find more of our recent publications and laboratory information in below website. Qualifications Candidates should have a Ph.D. or equivalent degree and experience with investigating biochemistry, cell biology, and molecular biology, as well as mouse models. Highly motivated candidates with publication records are encouraged to apply. Questions Or Additional Follow Up Can Be Sent To Wei Tong, Ph.D - View email address on click.appcast.io Professor and Distinguished Chair in Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine (UPENN), Co-Director, Hematopoietic Stem Cell program, Institute for Regenerative Medicine at UPENN Philadelphia, PA, USA #J-18808-Ljbffr University of Pennsylvania Perelman School of Medicine
- ...invites applications for a postdoctoral fellow position in the Tong laboratory to study genome maintenance in hematopoietic stem cells. The project emphasizes CRISPR/Cas9 screening to identify druggable targets related to replication stress and DNA repair. The work spans...For PostDoc
$65k
...myeloproliferative neoplasms A postdoctoral fellow position is available in the... ...Center. The laboratory studies how inherited genetic variation shapes hematopoietic stem cell (HSC) function, clonal... ...parallel reporter assays, CRISPR-based screens, and genome editing to test...For PostDocFull timeLocal areaAlbert Einstein College of Medicine
New York, NY13 hours ago- ...with an MD/PhD in bioengineering or related field to advance imaging and stem cell tools. Responsibilities include spatial imaging omics and integrating live-cell imaging with spatial omics to study stem cell and neuronal plasticity. The role focuses on engineering novel...For PostDoc
- The Malawi Longitudinal Study of Families and Health (MLSFH; at the University of Pennsylvania... ...processes that can inform policies The postdoc will work closely with Hans-Peter Kohler... .... Through this project, the postdoctoral fellow will gain access to newly collected 2026...For PostDocLive inLocal area
$72.5k - $80k
...collaborative Postdoctoral Fellow to join our research... ...validate Perturb-map CRISPR/perturbation libraries... ...tumor‑microenvironment cell populations. Cell culture... ...and arrayed CRISPR screens and functional assays.... ...through functional genomic studies. Apply spatial transcriptomics...For PostDocTraineeshipLocal area- ...The postdoctoral fellow will join a team of researchers seeking to identify serological... ...induction therapy. The incumbent will conduct studies of the anticryptococcal activity,... ...this individual includes experience with cell culture, imaging techniques, flow cytometry...For PostDocFull time
Albert Einstein College of Medicine
New York, NY2 days ago - ...recruiting a Postdoctoral Fellow. Our lab, affiliated... ...Neuroscience and Anesthesiology, studies the molecular... ...mouse models, advanced cell culture approaches, and... ...at the intersection of stem cell biology and molecular... ...as well as genome-wide screens using cutting-edge...For PostDocFull timeLocal area
$74.69k
...motivated Postdoctoral Fellows to join a dynamic,... ..., including cell-based, ex vivo, organoid... ..., and in vivo studies with viruses... ...protection, and host-cell fitness. Collaborate... ...propagation Viral entry, replication, neutralization,... ...assays CRISPR-based gene editing...For PostDocTraineeshipLocal area$72.5k - $80k
...Medicine at Mount Sinai in New York, is seeking postdoctoral fellows with expertise in calcium imaging, electrophysiology, developmental neuroscience, stem cell biology, and/or genomics/sequencing approaches to study cellular and molecular mechanisms that underlie the...For PostDocTraineeshipLocal area$50k
...Postdoctoral Fellow position is available in the “Spine Development and Regeneration” laboratory... .../protocols in research involving cell and molecular biology techniques, tissue... ...peer-reviewed publications are required. Postdocs will be eligible for a Postdoctoral position...For PostDocWorldwideHospital for Special Surgery
New York, NY2 days ago- ...Laboratory at Weill Cornell Medicine in New York seeks a postdoctoral researcher to study how hormonal signals and intracellular pathways control adipose tissue and pancreatic β-cells, integrating mechanistic cell biology with whole-animal physiology. Projects will combine...For PostDoc
$75k
...a highly motivated postdoctoral fellow with expertise in genome editing, mammalian cell culture, and cell differentiation... ...Experience in primary cell culture and stem cell differentiation is highly... ...The goal of our lab is to evolve CRISPR-based genome editing tools into...For PostDocFull time- Role: Postdoctoral Research Fellow in Systems Immunology focusing on vaccine adjuvant mechanisms and immune profiling.... ...profiling technologies. Responsibilities designing in vitro studies developing primary immune cell co-culture models characterizing immune responses via...For PostDoc
- ...Postdoctoral Position - Cancer Cell Cycle Biology and... ...is recruiting a postdoctoral fellow. We study how cancer cells regulate cell... ...with fluorescent biosensors, CRISPR functional genomics, and patient... ...Subsidized housing is available to postdocs through Columbia Residential...For PostDoc
- ...skilled and motivated molecular and cell biologists to be the drivers of our... ...both in vitro (induced pluripotent stem cell models) and in vivo systems (... ...functional genomics (e.g., siRNA, shRNA, CRISPR/Cas9, and chemogenomic) screens (preferred) Knowledge of...For PostDocFull timeImmediate start
$23.35 - $35.51 per hour
...approaches.- Flow cytometry and primary immune cell culture assays.**The Donlin laboratory**;... ...collaborative environment empowers postdocs to engage with global experts, spearhead... ...names for a reference survey.**Postdoctoral Fellow Salary****$68,812** with an **additional...For PostDocFull timeLocal areaShift workHospital for Special Surgery
New York, NY13 hours ago- Job Description An NIH-funded Postdoctoral Fellow position is available at the Icahn School... ...Sinai in New York City to participate in studies on the function of ligand activated... ...new therapies for anemias and other red cell disorders. The ability to modulate ex vivo...For PostDoc
$57 per hour
...Manager - Research Survey (ONET Occupation Study) is a remote review track for evaluating... ...team can train on it. Role details Track STEM research review Work model Remote ·... ...the program lead. Useful experience PhD, postdoc, or industry research experience in the topic...For PostDocFor contractorsRemote work10 hours per week- ...range of approaches (genetic, cell biological and in vivo modeling... ...efforts utilizing various screening strategies in collaboration with... ...strategies. The researcher will also study how the immune... ...strongly preferred. For postdoctoral fellow, MD, PhD or MD/PhD degree required...For PostDoc
Hanna Irie
New York, NY2 days ago - Postdoctoral Fellow in Senescence, Aging andInflammation Location: University of Pennsylvania... ...biology with single-cell RNA sequencing (scRNA-seq),10x Genomics Xenium... .... The fellow will participate in in vivo studies andanalyses of scRNA-seq and 10x Genomics...For PostDocLocal area
$72.5k - $80k
Postdoctoral Fellow in AI, Causal Inference, and Health Data Science Suarez-Farinas Lab -... ...healthcare. Responsibilities include designing studies, developing novel algorithms, analyzing... ...@mssm.edu) with the subject line "Postdoc Position." Equal Opportunity Employer The...For PostDocFull timeTraineeship$75k - $100k
...patients, at the right time. Postdoctoral Fellow This Postdoctoral Fellowship is designed... ...with genomic and pharmacological screening data, a huge computational environment, and... ...for an exceptional postdoctoral fellow to study and advance precision oncology using one...For PostDocRemote work- ...available for a highly motivated postdoctoral fellow to join an NIH R01–funded research... ...receptor (T2R) signaling in oral squamous cell carcinoma (OSCC) and tumor-associated macrophages... .... Experimental approaches will include studies using primary human monocyte-derived...For PostDoc
University of Pennsylvania Perelman School of Medicine
New York, NY13 hours ago $79.21k
Job Description Title: Postdoc Salary: $79,205 Department: Microbiology Physical work location... ...and hamsters. Methods to be included are cell culture of primary cells, molecular... ...development of novel model systems to study virus host interactions. Finally, you will...For PostDocTraineeshipLocal area- University of Pennsylvania’s Fuccillo Lab invites postdoctoral fellows to join a collaborative team studying how rodent cortico-basal ganglia circuits govern valence-, outcome- and sensory-guided actions. Fellows will work with in vivo recording/imaging, quantitative modeling...For PostDoc
- ...cancer immunity and heart repair. We are particularly interested in: The molecular mechanisms underlying vascular control of immune cell function in cancer and ischemic heart disease; Targeting myeloid cells to overcome cancer-associated immunosuppression; The biology...For PostDocTraineeshipVisa sponsorship
University of Pennsylvania Perelman School of Medicine
New York, NY13 hours ago $72.5k - $80k
...Description Salary: Postdoc base salary Department: Neuroscience Physical work location:... ...imaging, slice electrophysiology, and single-cell transcriptomics. The Postdoctoral Fellow will participate in research studies aimed at understanding the neural mechanisms...For PostDocTraineeshipLocal area$72.12k
...Earth, Environmental, and Climate Sciences. Candidates must have Ph.D. or expect to complete degree requirements by September 2027. Fellows are supported for 24 months with a $12,000 research allowance and an annual salary of $72,116. Successful candidates are encouraged...For PostDoc$71.56k - $78.01k
## Postdoctoral Fellow-Arthroplasty Research LabApplylocations: New York, NYtime type: Full timeposted on: Posted Todayjob requisition... ...by transducing a specific population of autologous skeletal stem cells to induce a blastema-like state, followed by implantation at the...For PostDocFull timeLocal areaShift work$150 per hour
...Role details STEM Professor is a remote review track for evaluating AI outputs across stem research reasoning, calculations, and... ...report drift to the program lead. Useful experience PhD, postdoc, or industry research experience in the topic area. Prior work...For PostDocFor contractorsRemote work10 hours per weekAI Trainer Jobs
New York, NY13 hours ago
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