Heme, Research Fellow
$197.4k - $296.2kVertex Pharmaceuticals
Vertex Pharmaceuticals seeks a physician-scientist to lead drug discovery and translational research for in vivo gene editing therapies targeting hemoglobinopathies. The role bridges clinical expertise with preclinical science to advance programs from proof-of-concept through IND-enabling studies and Phase 1/2 trials.
Responsibilities
- Lead scientific strategy for in vivo gene editing platforms including editing technologies, delivery, and tissue targeting
- Design and guide in vitro, ex vivo, and in vivo studies aligned with clinically meaningful biology outcomes
- Serve as physician-scientist leader for IND-enabling strategy in partnership with development and clinical teams
- Lead cross-functional project teams to establish goals, priorities, timelines, and decision points
- Interpret complex datasets and translate findings into clear program recommendations and development strategy
Requirements
- MD and/or PhD in relevant discipline with 11+ years in academic medicine, translational research, biotech, or pharma R&D
- Strong expertise in drug development, translational science, and disease biology
- Demonstrated scientific leadership, publication record, and ability to influence project direction
- Experience in cell and gene therapy, genome editing, or in vivo pharmacology
- Track record in hemoglobinopathies, translational therapeutics, gene therapy, or stem cell biology
Compensation: $197,400 - $296,200 base
Vacancy posted 4 days ago
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