Lead/Senior Bioinformatics Research Scientist (Clinical Genome Analyst)

Job Description
The department of Computational Biology is seeking a highly motivated individual to join our cutting-edge Clinical Cancer Genomics team at St Jude Children's Research Hospital.

Job Description

This Lead or Sr Bioinformatics Research Scientist will analyze and classify somatic and germline genetic alterations in pediatric cancer patients ascertained from whole-genome, whole-exome and transcriptome sequencing and present findings to molecular pathologists for sign-out. This scientist will also work closely with our bioinformatics pipeline and visualization teams to maintain, upgrade, and explore novel analytical approaches to aid molecular classification and clinical reporting for cancer patients. Cancer Genomics is a rapidly evolving field, which enables new assays to be developed and implemented in our clinical environment. Therefore, the successful candidate will also have opportunities to participate in applied research and development projects to improve our clinical testing.

The ideal candidate has a deep understanding of cancer biology and expertise in genomic and transcriptomic data analysis using NGS approaches. In addition to data analyses, the incumbent will assist with establishing and documenting best practices and standard operating procedures for common NGS tests employed in our service. Clinical genomics testing at St Jude meets CAP/CLIA requirements for accreditation and reporting. Prior experience within in a clinical environment and experience in clinical test development and validation is also highly desirable.

Recognized as a world leader in mapping and characterizing the genomic landscape of pediatric cancer, St Jude has developed state-of-art computational infrastructure, well-established analytical pipelines, and deep genomic analysis expertise with a track record both research and clinical application of NGS data as reflected in publications in top-tier biomedical journals such as Nature, NEJM, JAMA, Nature Genetics and Cancer Discovery.

Lead Bioinformatic Research Scientist

Minimum Education:

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.

• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).

• Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience.

• Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Senior Bioinformatic Research Scientist

Minimum Education:

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences, chemistry, genomics, biomedical sciences, cancer biology) or related field.

• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).

• Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.

• Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $125,840 - $238,160 per year for the role of Lead/Senior Bioinformatics Research Scientist (Clinical Genome Analyst).

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Diversity, Equity and Inclusion

St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment.

Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

St. Jude is an Equal Opportunity Employer

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