Lab Technician

Lab Technician – Molecular Biology & DNA Sequencing (Evening Shift)

Location: South San Francisco, CA Employment Type: Full-Time, Direct Hire Schedule: Monday–Friday, 4:00 PM–12:00 AM Work Arrangement: 100% Onsite Compensation: $70,000–$85,000 annually + equity

Position Overview

We are seeking an experienced Lab Technician to join a rapidly growing biotechnology company specializing in DNA and RNA sequencing technologies. This position supports high-throughput molecular biology laboratory operations, including sample processing, DNA extraction, purification, PCR, and sequencing library preparation.

The ideal candidate will have hands-on experience in a commercial or production laboratory environment, strong molecular biology skills, and the ability to work independently in a fast-paced, high-volume setting.

Key Responsibilities

• Process and prepare high volumes of biological samples for DNA sequencing, supporting approximately 1,000–3,500 samples per shift.
• Perform DNA extraction, purification, PCR, and sequencing library preparation.
• Operate laboratory equipment and automated liquid handling systems.
• Perform sample preparation using 96-well plate workflows and established laboratory protocols.
• Load sequencing libraries onto sequencing instruments and monitor sequencing runs.
• Conduct quality control checks to ensure sample integrity, accuracy, and reliable results.
• Troubleshoot laboratory equipment, failed samples, and workflow issues to maintain productivity.
• Maintain accurate sample tracking and documentation using laboratory information management systems (LIMS).
• Maintain laboratory equipment, reagents, and supplies.
• Collaborate with laboratory operations and technical teams to improve efficiency and laboratory workflows.

Required Qualifications

• Bachelor's or master's degree in Biology, Molecular Biology, Biotechnology, Biochemistry, or a related scientific field.
• Minimum of 2 years of hands-on experience in a commercial, production, or high-throughput laboratory environment following completion of a degree.
• Experience with DNA extraction, purification, PCR, and/or DNA sequencing workflows.
• Familiarity with molecular biology laboratory techniques and sample preparation.
• Ability to work independently, troubleshoot technical issues, and manage multiple laboratory tasks.
• Strong attention to detail, organizational skills, and commitment to quality.
• Ability to work onsite during the evening shift (4:00 PM–12:00 AM).
• Authorization to work in the United States without employer sponsorship.

Compensation & Benefits

• Competitive base salary of $70,000–$85,000 annually.
• Equity compensation.
• Full-time, direct-hire opportunity with a growing biotechnology organization.
• Opportunity to work with advanced sequencing technologies and laboratory automation.
• Collaborative, fast-paced laboratory environment with opportunities for professional development.