Clinical Lab Scientist - Per Diem

This position performs genomic test workflows and procedures in the Clinical Cancer Genomics Laboratory (CCGL), one of the four labs under Genetics and Genomics Services. CCGL's specialized molecular, genomic diagnostic tests have applications in oncology diagnosis and treatment selection. This position involves the operation of laboratory equipment, successful completion of documentation required for quality control, and transcription of test results such that results are accurately reported in a timely fashion. This position will also require the ability to successfully collaborate with faculty, staff, and appointed directors to troubleshoot errant results and malfunctioning laboratory equipment as needed. The qualified applicant is expected to follow established quality control procedures and participate in all associated tasks in the section. Furthermore, the qualified applicant will have a role in the evaluation and implementation of methods and instruments per the discretion of supervisory staff and faculty.

Genomics Services at UCSF Health aims to achieve the highest standards in patient care and genomic testing. The division includes four clinical testing laboratories that deliver a range of genetic and genomic diagnostic tests performed by highly trained subspecialists.

Key Responsibilities

% TIME

Is Essentia

(Y/N)l

Perform DNA and RNA extraction from FFPE sections and fresh specimens: This involves manual DNA and RNA extraction, automated scraping using Xyall, and automated co-extraction of DNA and RNA on the Hamilton STAR or KingFisher. Independently complete clinical patient testing protocols in a timely and reliable manner. Troubleshooting equipment errors.

65

Y

Perform other molecular techniques, such as FISH (fluorescent in-situ hybridization) and PCR-based testing, such as MLR, SID, and MLH1, on tumor DNA specimens, and assist the laboratory staff in the performance of these methods.

10

Y

Perform Next-Generation Sequencing-based tests: this involves extraction of DNA and RNA from FFPE sections or fresh specimens, library preparation, and capture following standardized procedures, and setting up sequencing runs on Illumina instrumentation. To obtain and track appropriate quality control metrics.

10

Y

Perform General lab duties:

Transcribe and report test results and to operate laboratory equipment to accurately generate test results. Initiate troubleshooting of errant laboratory equipment as needed. Follow established quality control procedures.

10

Y

Assist in developing new laboratory tests; evaluate and assist in implementing new assay methods in the laboratory and in improving the performance of already establish new assays

5

Y

Required Qualifications:

• BS degree in related field with a major in an appropriate field, and knowledge and abilities essential to the successful performance of duties assigned to the position
• Experience in high-volume complex laboratory
• Knowledge of DNA and RNA extraction methodologies, especially from FFPE tissues
• Knowledge of molecular testing including: PCR, quantitative PCR, sequencing, gel electrophoresis, FISH

Preferred Qualifications:

• Recent experience in a clinical laboratory using CLIA Molecular Diagnostic techniques and procedures
• Recent experience in a clinical laboratory using APeX (Epic) and/or EPIC Beaker
• Experience working in a CLIA molecular laboratory
• 2 years of Next Generation Sequencing experience, including knowledge of library preparation techniques
• Experience with automation, including Hamilton liquid handler Automated Workstation

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available here.

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

Salary Information

The final salary and offer components are subject to additional approvals based on UC policy.

Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.

To learn more about the benefits of working at UCSF, including total compensation, please visit:

Required Qualifications:

• BS degree in related field with a major in an appropriate field, and knowledge and abilities essential to the successful performance of duties assigned to the position
• Experience in high-volume complex laboratory
• Knowledge of DNA and RNA extraction methodologies, especially from FFPE tissues
• Knowledge of molecular testing including: PCR, quantitative PCR, sequencing, gel electrophoresis, FISH

Preferred Qualifications:

• Recent experience in a clinical laboratory using CLIA Molecular Diagnostic techniques and procedures
• Recent experience in a clinical laboratory using APeX (Epic) and/or EPIC Beaker
• Experience working in a CLIA molecular laboratory
• 2 years of Next Generation Sequencing experience, including knowledge of library preparation techniques
• Experience with automation, including Hamilton liquid handler Automated Workstation