Sr. Software Engineer/Tech Lead, Data & AI Engineering US Remote

Sr. Software Engineer/Tech Lead, Data & AI Engineering US Remote About the Role Natera is a global leader in cell-free DNA testing, serving patients across oncology, women’s health, and organ health. Our Data & AI organization builds the enterprise data platform and AI systems that turn clinical, genomic, and operational data into products that improve patient care and accelerate the business. We are looking for a Data & AI Engineering Tech Lead to set the technical direction for a solutions team that builds analytics and AI solutions directly for business stakeholders: data and AI pipelines, data models, semantic layers, and the agents, dashboards, and data products that sit on top of them. This is a hands‑on, senior individual contributor role: you will write production code, own architecture and design decisions for the solutions your team delivers, and raise the engineering bar through design leadership, code review, and mentorship. This team is AI‑native by design. We expect engineers to use AI coding harnesses and agentic tooling as a core part of how they build, test, document, and operate solutions, and we expect the Tech Lead to model and scale those practices across the team. You will work in a regulated environment where data quality, lineage, and privacy are core requirements of every solution we ship. The ideal candidate is a strong engineer first, with a product mindset toward business outcomes, the judgment to make pragmatic architectural tradeoffs, and the communication skills to align engineers, product managers, and business stakeholders around them. Key Responsibilities Technical Leadership & Architecture Own the technical design and architecture for the analytics and AI solutions your team delivers; drive design reviews and make build-vs-buy and technology decisions in partnership with the data platform and architecture teams. Translate business stakeholder needs into well‑scoped technical designs, breaking down complex analytics initiatives into deliverable milestones for the team. Establish and enforce engineering standards for modeling, pipeline design, testing, CI/CD, and observability so solutions are built consistently and reusably across business domains. Hands‑On Solutions Engineering Design, build, and maintain scalable data pipelines and transformations on our cloud data platform, sourcing clinical, laboratory, operational, and commercial data to serve business analytics. Develop governed data models and semantic layers that power self‑service analytics, dashboards, and data products (e.g., Patient 360, Provider 360, Test 360) for business teams. Develop AI solutions to enable business productivity and automation through use of agentic workflows, RAG/retrieval, and LLM pipelines (extraction/classification) Write production‑grade SQL and Python; contribute to shared frameworks, templates, and tooling that let the team deliver new analytics solutions faster. Ensure the data layer supports performant, trustworthy analytics and LLM querying ; lead root‑cause analysis on complex data issues and drive durable fixes. AI‑Native Ways of Working & Mentorship Use AI coding assistants and agentic tools daily across the development lifecycle—design, coding, testing, documentation, and operations—and measurably increase your own and the team’s throughput. Define and scale the team’s AI‑native engineering practices: prompt and context patterns, reusable agent workflows, AI‑assisted testing and review, and the guardrails that keep quality and compliance intact. Mentor and grow engineers through code review, pairing, and design coaching; partner with the engineering manager on technical hiring, onboarding, and skills development. Data Quality, Reliability & Compliance Implement data quality checks, contracts, lineage, and monitoring so that downstream consumers can trust the data by default. Own operational excellence for the team’s solutions: SLAs, incident response, and cost efficiency of compute and storage. Ensure pipelines handling PHI and genomic data meet HIPAA, CLIA, and internal security and governance requirements, including access controls, auditability, and retention. Cross‑Functional Partnership Work directly with business stakeholders across functions to understand their questions, shape analytics solutions to their needs, and communicate technical tradeoffs in plain language. Collaborate with data platforms and AI platform teams to ensure solutions build on shared foundations rather than one‑off pipelines. Represent the team in architecture forums, data governance discussions, and tool evaluations. Qualifications Required 7+ years of data or software engineering experience, including 2+ years leading technical design and delivery for a team or major workstream, ideally building analytics solutions for business users. Demonstrated ability to mentor engineers, run effective design and code reviews, drive technical consensus, and communicate clearly with technical and non‑technical audiences. Demonstrated, hands‑on use of AI coding assistants and agentic tools in daily engineering work, with a point of view on how to use them well. Expert‑level SQL and strong Python, with a track record of shipping and operating production data pipelines and data models at scale. Deep experience with a modern cloud data warehouse and cloud infrastructure (Snowflake/AWS preferred). Hands‑on experience with transformation frameworks (dbt or equivalent) and workflow orchestration (Airflow, Dagster, Prefect, or similar). 1‑2 years of practical background building with LLM frameworks (LangChain, LangGraph, or equivalent) alongside managed AI services and model routing gateways like Snowflake Cortex, AWS Bedrock, and foundational APIs. Strong grounding in analytical data modeling (dimensional or domain‑driven), semantic layers, data quality engineering, and CI/CD for data systems. Preferred Experience in healthcare, life sciences, or another regulated domain handling PHI or other sensitive data. Experience with lab data management systems, lab informatics systems, bioinformatics pipelines is a plus Snowflake experience, including performance tuning, cost management, and features such as dynamic tables, Snowpark, or Cortex. Sigma experience, or experience with comparable BI and semantic‑layer tools (Looker, Tableau, Power BI), and an understanding of how to design data models for self‑service consumption. Experience building and operating agentic or LLM‑based workflows within the data development lifecycle. Experience with infrastructure‑as‑code (Terraform) and data observability tooling. Experience integrating with Salesforce, laboratory information systems, or EHR data sources. Bachelor’s or Master’s degree in Computer Science, Engineering, or a related quantitative field, or equivalent practical experience. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA

$150,400 - $188,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell‑free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world‑class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Natera values transparency and fair hiring practices. Disclosure of a family relationship does not automatically disqualify you from employment. This information helps us comply with our internal policies on conflicts of interest and reporting structures. Voluntary Self‑Identification For government reporting purposes, we ask candidates to respond to the below self‑identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Natera’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service—connected disability. A "recently separated veteran" means any veteran during the three‐year period beginning on the date of such veteran’s discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985. #J-18808-Ljbffr Natera