Project Engineer
$125k - $135kInitial Therapeutics, Inc.
Expect to grow, personally and professionally: At Siegfried, we offer exciting challenges and ample opportunities to showcase your talents. As a trusted and respected partner to the pharmaceutical industry, we uphold the highest standards in safety, quality and sustainability, while fostering a culture that empowers you to thrive. Join a rapidly expanding global company, where diverse perspectives and experiences come together in a collaborative environment. Here, you’ll find a workplace that values both collective success and your individual contributions—offering long‑term opportunities to grow and make an impact. Your Role The Project Engineer III is responsible for leading and executing capital investment (CAPEX) projects and strategic engineering initiatives that support manufacturing operations, facility expansion, equipment upgrades, process improvements, and new product introductions within a highly regulated pharmaceutical environment. This role provides technical leadership throughout the full project lifecycle, from concept development and design through commissioning, qualification, validation, implementation, and ongoing operational support. As a subject matter expert, Project Engineer III supports new product introductions, equipment lifecycle management, process optimization, and infrastructure expansion projects. This role requires strong technical expertise in pharmaceutical manufacturing systems, commissioning and qualification practices, project management, and engineering problem‑solving, with the ability to influence cross‑functional teams and deliver sustainable business results. The successful candidate will demonstrate a combination of project leadership, engineering excellence, and hands‑on technical capability to enhance manufacturing performance, improve equipment reliability, maintain regulatory compliance, and support the organization’s long‑term growth objectives. Your Profile Key Responsibilities Project Management & Capital Execution Lead and manage CAPEX projects from concept through completion, including facility expansions, utility upgrades, equipment installations, manufacturing process improvements, and infrastructure enhancements. Develop project charters, business justifications, budgets, schedules, resource plans, and risk mitigation strategies. Monitor project progress, spending, and milestones to ensure projects are delivered safely, on schedule, and within budget. Coordinate internal stakeholders, contractors, OEMs, consultants, and suppliers throughout the project lifecycle. Develop detailed project plans and oversee implementation of equipment, process, and facility upgrades. Equipment Commissioning, Qualification & Validation Lead and coordinate equipment commissioning, qualification, and validation activities in accordance with GMP and validation lifecycle requirements. Develop and review User Requirement Specifications (URS), Design Qualification (DQ), Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ) protocols and reports. Support Computer System Validation (CSV) and Data Integrity initiatives where applicable. Coordinate and execute Factory Acceptance Testing (FAT) and Site Acceptance Testing (SAT) activities for new equipment and systems. Ensure qualification documentation is complete, accurate, and audit ready. Engineering Support & Continuous Improvement Conduct engineering investigations and provide technical leadership in the resolution of deviations, non‑conformances, quality events, and CAPAs. Perform root cause analysis and implement sustainable corrective and preventive actions. Evaluate process performance, equipment reliability, and operational metrics to identify improvement opportunities. Develop and implement engineering solutions that improve process robustness, product quality, safety, and manufacturing efficiency. Analyze equipment and process performance trends to proactively identify and address operational risks. Technical Documentation & Compliance Develop, review, approve, and maintain engineering documentation including SOPs, maintenance procedures, calibration procedures, specifications, drawings, P&IDs, equipment files, and technical reports. Ensure engineering activities comply with GMP, FDA, EU, ISO, and internal quality system requirements. Maintain accurate project documentation, change control records, validation files, engineering drawings, and asset documentation. Support internal and external audits and regulatory inspections as a subject matter expert. Cross‑Functional Collaboration & Leadership Collaborate with Manufacturing, Quality Assurance, Validation, Maintenance, Supply Chain, EHS, and Regulatory Affairs to support business objectives. Facilitate communication among project teams and functional stakeholders to ensure alignment and successful project execution. Lead project meetings and present project status, risks, budgets, timelines, and technical recommendations to management. Mentor and train operators, technicians, and inspectors on equipment operation, troubleshooting, process controls, and inspection techniques. Provide technical support and engineering expertise to maintenance, operations, and project management teams. Participate in strategic planning activities related to facility capacity, manufacturing expansion, and technology implementation. Required Education and Experience Bachelor’s degree in Mechanical Engineering, Chemical Engineering, Industrial Engineering, Pharmaceutical Engineering, or a related engineering discipline. Minimum 4 years of engineering experience within the pharmaceutical, biotechnology, medical device, or other highly regulated manufacturing industries. Minimum 2 years of direct experience in equipment commissioning, qualification, and validation (CQV). Proven experience managing CAPEX projects involving manufacturing equipment, cleanroom facilities, utility systems, and process improvements. Demonstrated experience supporting GMP‑regulated manufacturing environments. Hands‑on experience with equipment installation, startup, troubleshooting, and qualification activities. Experience working in classified cleanroom environments. Strong understanding of pharmaceutical manufacturing processes and quality systems. Experience interacting with external vendors, contractors, and regulatory auditors preferred. Target Salary Range: $125,000 - 135,000 Individual compensation packages are based on various factors unique to each candidate, including skill set, experience, qualifications and other job‑related reasons. Your Benefits Medical, Dental, Vision Flexible Spending & HSA Options Life Insurance, Short & Long Term Disability Pet Insurance 401K Founded in 1873 in Zofingen, Switzerland, Siegfried has grown into a global network of 16 sites across three continents. With a team of more than 4,200 highly skilled professionals, we take the innovations of our pharmaceutical customers to industrial scale and manufacture safe drugs for patients worldwide. As a fully integrated CDMO, Siegfried is one of the few organizations today that can carry out the development and manufacturing of APIs and finished dosage forms under one roof. This unique combination of know‑how and experience makes us the most trusted partner in the pharmaceutical industry. #J-18808-Ljbffr
$110k - $130k
...and opportunities. We currently have an opportunity for a Field Engineer II in Souther California to assist in one of our biggest... ...5 North near Santa Clarita. ResponsibilitiesWorks closely with Project Managers, Superintendents, Foreman and Crews on Project Deliverables...SuggestedContract workFor subcontractorWork at office$125k - $155k
Overview Shimmick is seeking a Project Engineer in Palmdale, California to support the Palmdale Water Reclamation Plant Influent Pump Station Modification project. This project for the Los Angeles County Sanitation District (LACSD) includes upgrades to influent pumping...SuggestedFull timeFor subcontractorFlexible hours$97.7k - $144.4k
...duties as assigned.Required QualificationsB.S. in Electrical Engineering or relevant discipline2+ years relevant application experience... ...experienceProject engineering experienceWorking knowledge of Vision or other project management tracking softwareFocus Area = ProtectionProtection...SuggestedFull timeApprenticeshipFlexible hours$103.66k - $162.89k
...profileMechanics - Mechanical part or subassembly designJob titleProject Engineer 3Employment typePermanentProfessional categoryProfessional,... ...-class team to reinvent in-flight experience. In the role of Project Engineer 3, you'll play a pivotal part on our Engineering team....SuggestedPermanent employmentWork at officeLocal areaWorldwide$112k - $149k
...procurement, receiving, inventory, configuration, asset tracking, project allocation, and deployment- Stage, ship, and track hardware... ...- Drive issues, questions, and action items to closure across engineering, program, and supplier stakeholders- Manage supplier...SuggestedFull timeWork experience placementImmediate start- ...centers to modernizing transmission systems, our industry-recognized engineers and scientists have been at the forefront of grid... ...our energy future.HDR Engineering is looking for a Substation Project Structural Engineer to join our growing and nationally ranked team...Work at office
$146k - $194k
...production acceptance testing, software qualification testing and much more. This position is looking for a highly motivated Project Engineer with emphasis in testing of software/hardware interfaces, networking, and diagnostics. If you are interested in an extremely innovative...Full timeWork experience placementImmediate start$85k - $123.3k
...the world’s leading integrated design practice. Our architects, engineers, interior designers, consultants, sustainability specialists,... ...culture and our innovative, sustainable approach to projects help us create buildings that matter to our world.Together, we...Full timeTemporary workPart timeFor contractorsCasual workWork at office$113k - $149k
...Projecting Engineering Anduril Industries is a defense technology company with a mission to transform U.S. and allied military capabilities with advanced technology. By bringing the expertise, technology, and business model of the 21st century's most innovative companies...Full timeWork experience placementImmediate start- ...Project Engineer Irvine, CA * Please Note: Uprite Construction is not accepting resumes from third-party agencies for this position. Any unsolicited resumes will be considered Uprite Construction's property, and no fees will be paid for unsolicited referrals.*...For subcontractorInternshipWork at officeLocal area
- ...Project Engineer From its inception in 1991, Weaver Consultants Group has been founded upon the tenets of attentive and responsive customer service, strong project management, and solid internal financial controls. The quality of our people, our focus on understanding...For subcontractorWork at officeLocal areaShift work
$70k - $95k
...Project Engineer Department: Project Engineer Employment Type: Full Time Location: Irvine, CA Compensation: $70,000 - $95,000 / year Description The primary function of the Project Engineer is to assist the project team in the administration and...Permanent employmentFull timeContract workTemporary workFor subcontractorWork at office$120k - $170k
...we're well-positioned to lead during a time of rapid change. As project delivery models, regulatory frameworks, supply chains, and... ...construction approach is essential to our success. The Project Engineer supports the successful planning and execution of infrastructure...Full timeFor subcontractorFlexible hours$90k - $115k
...without visa sponsorship or transfers now or in the future Rudolph & Sletten, a Tutor Perini Company, is seeking to hire a Project Engineer to join our office in Los Angeles or Irvine, CA. About Rudolph & Sletten In the last six decades, Rudolph and Sletten...Full timeContract workFor contractorsFor subcontractorVisa sponsorship- ...Project Engineer Purpose: To provide project design in AutoCAD Civil 3D, including plans, calculations, specifications, and estimates for entire projects and portions of larger projects, with moderate direction from senior staff. Duties and Responsibilities:...
$125k - $135k
## Project Engineer IIIApplylocations: Irvine, CAtime type: Full timeposted on: Posted 2 Days Agojob requisition id: R26\_595"Expect to grow", personally and professionally: At Siegfried, we offer exciting challenges and ample opportunities to showcase your talents. As...Temporary workFor contractorsFlexible hours- ...centers to modernizing transmission systems, our industry-recognized engineers and scientists have been at the forefront of grid... ...mark on our energy future.The primary duties of the Substation Project Engineer include responsibility for knowledge and execution of...Work at officeLocal area
$108k - $170k
...to create positive water outcomes that respect nature and nurture communities.Who are we looking for? GHD is seeking a Senior Project Engineer - Water Treatment to join our team based in either our Irvine, CA or Phoenix, AZ office. We are seeking someone with experience...Contract workFor contractorsWork at office$80k - $110k
...specializing in representing occupiers, never landlords. Our Program, Project & Construction Management practice serves as owner's... ...expertise.We are currently seeking a Senior Construction Project Engineer to join our Irvine team, embedded in an exciting long-term engagement...Contract workWork at officeShift work$126.42k - $220.73k
...innovation in sustainable infrastructure and our expertise in engineering, procurement, consulting and construction, together we are building... ...Relocation eligible : Yes Full time/Part time : Full-Time Project Only Hire : No Visa Sponsorship Available: No Why Black &...Full timePart timeWork experience placementWork at officeLocal areaWorldwideRelocationVisa sponsorshipFlexible hours$96.75k - $140k
...Langan provides expert land development engineering and environmental consulting services for major developers, renewable energy producers... ...contributions. Job Summary Langan is seeking a Project Civil Engineer join its collaborative team in Irvine or Los...Hourly payFull timeTemporary workWork experience placementWork at officeLocal areaWorldwideFlexible hours$170k - $205k
A Day in Your Life at MKS:We are seeking a Sr. Manager, Project Engineering, who will lead the management and execution of cross-functional Product Development Process (PDP) projects collaborating with internal and external stakeholders and customers.You Will Make an Impact...Permanent employmentFull timeVisa sponsorshipWork visaRelocation package$125k - $160k
...Senior Project Engineer ARB Industrial is seeking a Senior Project Engineer to support the execution of EPC power generation and energy storage projects across its portfolio. This is a key project leadership role reporting directly to the Project Manager and serving...Daily paidFor contractorsFor subcontractorWork at office- ...Senior Project Engineer TransGrid Energy is seeking an ambitious and passionate Senior Project Engineer to join our team and will be responsible for leading and working with EPC Partners, Transmission Providers, IOUs and TGE's off-take customers to ensure successful...For contractorsWork experience placementWork at office
$105k - $125k
...Senior Project Engineer We're looking for an experienced Senior Project Engineer with 6+ years of land development design experience to join our Cardiff team. If you're passionate about designing and developing thriving communities and want to work with a like-minded...Work at officeLocal area$80k - $120k
...Project Engineer Location: Costa Mesa, CA, 92626 Country: United States Salary: $80000-$120000 Start Date: Description: About the job Are you a passionate Civil Engineer looking for an exciting opportunity to grow with other like-minded individuals...Full timeWork at officeRelocation$70k - $85k
Apply for the Project Engineer role at JRM Construction Management . JRM is a leading General Contracting and Construction Management firm with offices in New York, New Jersey, California, and Florida. We serve city and state agencies, Fortune 500 corporations, and major...Work experience placementFor subcontractorWork at office$100k - $145k
...the world’s leading integrated design practice. Our architects, engineers, interior designers, consultants, sustainability specialists,... ...culture and our innovative, sustainable approach to projects help us create buildings that matter to our world. Together...Full timeTemporary workPart timeFor contractorsCasual workWork at office- ...Structural Project Engineer You'll Come for a Job…But You'll Stay for an Exciting Career! Engineering and Designing Reliable, Responsive, Solutions. SINCE 1976, CANNON has provided creative solutions to clients in the energy industry, water resources, public infrastructure...Work at officeRemote workRelocation package
- ...Job Description Job Description Summary A growing construction advisory firm is seeking an Senior Project Engineer to support construction lending and owner's representative projects from preconstruction through closeout. The firm works on behalf of banks, lenders...For contractorsWork at officeRelocation package
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Project Engineer. Be the first to apply!
- data center project engineer Irvine, CA
- senior project engineer Irvine, CA
- project application engineer Irvine, CA
- project engineer Irvine, CA
- sr project engineer Irvine, CA
- information technology project engineer Irvine, CA
- implementation project manager remote Irvine, CA
- projects work from home Irvine, CA
- architectural project designer Irvine, CA
- project finance Irvine, CA



