Bioinformatician, Operational Support

We believe in career development and empowering our employees. Not only do we provide career coaches internally, but we offer many training opportunities to expand your knowledge base! We have highly competitive benefits with a variety HMO and PPO options. We have company 401k match along with an Employee Stock Purchase Program. We have tuition reimbursement, leadership development, and even start employees off with 16 days of paid time off plus holidays. We offer wellness courses and have highly engaged employee resource groups. Come join the Neo team and be part of our amazing World Class Culture! Position Summary As a Bioinformatician, Operational Support, you provide essential bioinformatics support for wet‑lab operations, with a primary focus on the monitoring, maintenance, and troubleshooting of production next‑generation sequencing (NGS) pipelines. You will be embedded within a CAP-, CLIA-, and NY State‑registered clinical laboratory and play a critical role in ensuring the accuracy, reliability, and regulatory compliance of genomic data workflows. Responsibilities Monitor production NGS pipelines on a daily basis to ensure successful execution and data integrity Identify, triage, and resolve pipeline failures, data quality issues, and workflow bottlenecks in a timely manner Collaborate with wet‑lab scientists to diagnose sequencing and data processing issues and elevate as needed Track pipeline performance metrics and generate routine status reports for laboratory and quality teams Support onboarding and validation of new sample types, assays, or sequencing instruments into existing pipelines Operate within the quality management framework of a CAP/CLIA/NY State‑accredited laboratory Maintain thorough documentation of pipeline activities, changes, and incident reports in accordance with regulatory requirements Assist in the development and review of standard operating procedures (SOPs) related to bioinformatics workflows Participate in internal audits, proficiency testing, and quality review activities as requested Contribute to pipeline development and optimization projects under the guidance of senior bioinformaticians Write and maintain scripts in Python and/or R to automate data processing, QC, and reporting tasks Education, Experience & Qualifications Bachelor’s or Master’s degree in Bioinformatics, Computational Biology, Genomics, Computer Science, or a closely related field — or an equivalent combination of education and relevant professional experience At least 2 years of hands‑on experience with NGS data analysis workflows (academic research, internship, or industry); advanced degree may substitute for experience Working proficiency in Python and/or R for data manipulation, scripting, and analysis Familiarity with common NGS file formats (FASTQ, BAM, VCF) and bioinformatics tools (e.g., BWA, GATK, samtools, or equivalent) Strong troubleshooting and problem‑solving skills with a systematic, documentation‑driven approach Excellent written and verbal communication skills; ability to collaborate effectively with both scientific and non‑scientific colleagues Experience working in or supporting a CAP-, CLIA-, and/or NY State-regulated clinical or diagnostic laboratory Familiarity with quality management systems (QMS), SOPs, or laboratory compliance documentation Exposure to workflow management systems such as Nextflow, Snakemake, or WDL/Cromwell Knowledge of clinical genomics applications (oncology, rare disease, pharmacogenomics, etc.) #J-18808-Ljbffr