HPC Systems Engineer
Nextonic Solutions LLC
Nextonic Solutions is seeking a High-Performance Computing (HPC) Systems Engineer to join our vibrant team at the National Institutes of Health (NIH) supporting the The National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD. The High-Performance Computing (HPC) Systems Engineer will support the Scientific Computing and Informatics (SCI) team at The National Center for Advancing Translational Sciences (NCATS). This role will focus on the design, optimization, security, and maintenance of HPC and cloud-based infrastructures that enable cutting-edge biomedical research through scalable, secure, and high-performing computing environments. Responsibilities Design, configure, and maintain scalable HPC clusters for optimal performance. Support documentation and ATO (Authority to Operate) processes. Ensure infrastructure design compliance with federal security standards and best practices. Implement monitoring tools such as XDMoD for transparency and user reporting. Integrate platforms such as JupyterHub and job schedulers (e.g., Slurm) for improved interactivity. Develop and manage AWS-based infrastructure using Terraform, Packer, and Ansible. Automate deployment workflows to streamline provisioning, updates, and scaling. Manage systems involved in AWS Secure Cloud Bridging (SCB) and STRIDES initiatives. Implement CIS benchmark-aligned system hardening using OpenSCAP. Administer optimized compute images (CPU/GPU) for scientific workflows. Leverage tools such as OpenHPC, Warewulf, and Ansible for environment management. Lead and coordinate quarterly patch cycles. Partner with researchers and external stakeholders on critical projects. Facilitate solution transitions to other NIH centers and collaborators. Contribute to publications and team objectives through deep technical engagement. Qualifications Federal ATO processes experience required. HPC architecture and performance optimization is required. Scientific software development and deployment. High-speed network and parallel file system architecture. Troubleshooting, diagnostics, and technical support. Strong communication and multitasking skills. Programming & Scripting Languages - Pascal, BASIC, Delphi, Visual Basic, C, C++ Scripting - Bash, Perl, Python, Ruby, PEAR, Tcl Systems & Network Administration Windows – 95–10; NT–Server 2016 Networking – Active Directory, TCP/IP v4/v6, DHCP, DNS, WINS Legacy – NOVELL 3.1–5, VPN, Citrix, Terminal Services Monitoring & Management Tools Infrastructure & Automation Red Hat Satellite, Kickstart, RPM optimization File Systems & Archiving HPC Tools & Job Scheduling Nice DCV, EnginFrame, VNC, OpenText Exceed OnDemand, Web Remote Desktop Containerization & GPU Databases SQL Server (2000–2008), MySQL, Zope High-Speed Networking HPC architecture and performance tuning Cybersecurity in HPC/cloud environments Infrastructure as Code (AWS, Terraform, Ansible, Packer) Supporting scientific workflows in research environments #J-18808-Ljbffr
- A technology solutions provider is seeking a High-Performance Computing (HPC) Systems Engineer to support the NIH’s NCATS in Rockville, MD. This position involves designing and maintaining HPC infrastructures to enhance biomedical research. Candidates should have experience...Suggested
$87.1k - $157.45k
Description Leidos is looking for a mid-career Systems Engineer (Mid-Career) - HPC & GPU Infrastructure with a deep understanding of operating systems, hardware, Kubernetes, and NVIDIA GPU products. As a Systems Engineer - HPC & GPU Infrastructure, you will play a pivotal...Suggested$87.1k - $157.45k
Leidos, located in Bethesda, MD, seeks a Mid-Career Systems Engineer specializing in HPC & GPU Infrastructure. This on-site position involves designing and optimizing GPU clusters for the Intelligence Community. The ideal candidate will have a Bachelor’s degree in Computer...Suggested- Leidos Inc in Bethesda, Maryland is seeking a Junior Systems Engineer for HPC and GPU Infrastructure. This role involves designing and optimizing GPU clusters for the IC community customers, requiring a strong background in Linux and hardware integration. The ideal candidate...Suggested
- ...CommVault Systems Engineer (Data Protection / Backup) Employment Type: Full-Time, Experienced Department: Technology Support CGS is seeking an experienced CommVault Data Protection Engineer with extensive knowledge and experience in designing, developing, configuring,...SuggestedFull timeFlexible hours
$145k - $170k
Microreactor System Engineer X-energy LLC is hiring Microreactor System Engineers to join its team. This role is responsible for executing rigorous systems engineering processes to support the design, integration, and management of complex nuclear systems throughout their...Work at officeMonday to Friday$120k - $140k
Job Description This role is responsible for executing rigorous systems engineering processes to support the design, integration, and management of complex nuclear systems throughout their lifecycles. Working within established model-based systems engineering frameworks...Work at officeMonday to Friday$120k - $145k
Job Description Systems Engineer to join the team responsible for executing rigorous systems engineering processes to support the design, integration, and management of complex nuclear systems throughout their lifecycles. Roles and Responsibilities Apply systems thinking...Full timeWork at officeMonday to Friday- X-Energy, LLC is hiring a Microreactor Systems Engineer located in Rockville, MD. The successful candidate will lead systems engineering processes for complex nuclear projects, ensuring integration and management through their lifecycle. Responsibilities include managing...
$87.1k - $157.45k
...Leidos is currently seeking a Software Specialist to join our team. Primary Responsibilities Duties include analysis of systems requirements, timelines, requirements allocation, defining interfaces, system testing and integration and quality assurance. Responsible...Local areaImmediate start- Alumni Ventures is seeking a Systems Engineer responsible for executing rigorous systems engineering processes to integrate and manage complex systems. You will lead efforts in stakeholder analysis, requirements identification, and design integration, ensuring all components...
- X-energy is seeking experienced Systems Engineers in Rockville, MD. The role emphasizes rigorous systems engineering processes to design and manage complex nuclear systems. Responsibilities include managing lifecycle efforts, stakeholder analysis, and using model-based...
$131.3k - $237.35k
...work, let Leidos show how to accelerate your career path. Leidos has an exciting opening for you as our next TS/SCI Senior Systems Engineer supporting DIA’s National Digital Exploitation and OSINT Center (NDOC) (formerly NMEC) under our 10-year DOMEX Technology...Contract workLocal areaImmediate startRemote workFlexible hours$107.9k - $195.05k
...Description Job Description (ENG1018T – Infrastructure and Lab Engineering Architect) Job Description (ENG1018T4 – Infrastructure & Lab... ...for factory lab initiatives, working closely with software, systems, network engineers and program leadership to ensure lab...Work at officeLocal areaImmediate start$97.01k - $164.91k
...Job Description BAE Systems is seeking a full time Systems Engineer (w/Modeling focus) to support our work as a prime contractor on a high-profile U.S. Navy weapon system. As part of the Interfaces Management team, the selected candidate is expected to demonstrate a...Full timeFor contractorsWork experience placementLocal area$100k - $140k
X-energy LLC is hiring a mid-level Chemical Engineer in Rockville, MD. This role entails designing, implementing, and optimizing chemical processes, with an emphasis on thermal-hydraulic systems for High-Temperature Gas-cooled Reactors (HTGRs). Candidates should have a...$77k - $95k
Supernus Pharmaceuticals Inc in Rockville, MD seeks a GxP and Lab Systems Administrator. The role involves troubleshooting and maintaining lab applications, ensuring compliance with GxP standards. Candidates should have a BA/BS in computer science or equivalent, along with...$132.96k - $226.04k
...Senior Principal Program Systems Engineer BAE Systems is seeking a Senior Principal Program Systems Engineer with specialized experience in DoW programs to support our work as a prime contractor on a high-profile U.S. Navy weapon system. The candidate will have extensive...Full timeFor contractorsLocal area$97.01k - $164.91k
...Cybersecurity Systems Engineer BAE Systems is seeking an experienced Systems Engineer to support our work as a prime contractor on a high-profile U.S. Navy weapon system. Serving as the Cybersecurity Systems Engineer, you will influence a multi-disciplinary team responsible...Full timeContract workFor contractorsLocal area- Position Overview We are looking for an experienced Systems Administrator/Engineer who is passionate about initiating, orchestrating and implementing various IT solutions. As a mid-to-senior level IT systems engineer you will be a “jack-of-all-trades,” expected to be familiar...
- X-Energy, LLC is seeking a Microreactor System Engineer in Rockville, MD. The position involves executing systems engineering processes to support complex nuclear system design and management. Applicants should have a Bachelor's degree in engineering and at least ten years...
$180k - $220k
...security, civil, and commercial missions where propulsion capability and rapid execution matter. We are hiring a Spacecraft Mission Systems Engineer to serve as a technical owner across spacecraft development, from early mission architecture through flight delivery. This is...Permanent employment$131.3k - $237.35k
...Description Leidos is seeking a Senior Systems Engineer / Product Owner to join the Air Traffic Business Area within the Homeland Sector located in either Gaithersburg, MD or Egg Harbor Township, NJ , supporting the development of the Leidos Common Baseline....Local areaImmediate startRemote work$107.9k - $195.05k
...Kinetic Effects Business Area, part of the Defense Sector at Leidos, currently has an opening for a cleared Senior Model-Based Systems Engineer to work in our Arlington, VA office. This is an exciting opportunity to use your experience helping multiple DoD customers...Work at officeLocal areaImmediate start$131.3k - $237.35k
...Description Leidos has a new and exciting opportunity for an Enterprise Architect/Systems Engineer in our Intel Sector Analysis Solutions Business Area (ASBA) . Our talented team is at the forefront in Security Engineering, Computer Network Operations (CNO), Mission...Local areaImmediate startFlexible hours$107.9k - $195.05k
...Leidos is seeking a Systems Engineering Manager to lead a multidisciplinary team of 12‑15 systems engineers, developers, and DevSecOps personnel within an Agile Release Train (ART) for the Air Traffic Business Area within the Homeland Sector. The role focuses on building...For subcontractorRemote work$107.9k - $195.05k
...Description Lead design, implementation, and lifecycle management of enterprise systems and infrastructure. Serve as technical authority and hands-on engineer for systems architecture, integration, performance, security, and reliability. Mentor engineers and administrators...Local areaImmediate start$83k - $108k
...TSC is seeking an entry level engineer Systems Engineer I to support development, testing, and assessment of Navy sensors and combat systems in Silver Spring, MD. This position will focus on development and use of model and simulation of Navy Anti-Air Warfare (AAW) and...Flexible hours- Alumni Ventures is looking for a Systems Engineer in Rockville, MD, to oversee the systems engineering processes for nuclear systems. The role involves working within established frameworks to ensure components meet project requirements and maintain thorough documentation...
$90k - $172k
...Radar Systems Engineer TSC in Silver Spring, MD, is seeking a Radar Systems Engineer to support activities related to Model and Simulation of the Navy’s Combat Systems. This position will focus on customer interactions and task management for M&S development and testing...Contract workRelocationFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to HPC Systems Engineer. Be the first to apply!
- application system engineer Rockville, MD
- senior windows systems engineer Rockville, MD
- system performance engineer Rockville, MD
- senior staff systems engineer Rockville, MD
- systems engineer Rockville, MD
- computer system validation engineer Rockville, MD
- system engineer remote Rockville, MD
- software system engineer Rockville, MD
- operations support system engineer Rockville, MD
- operating system engineer Rockville, MD


