Clinical Trial Manager

Clinical Trial Manager (CTM)Join Immatics and shape the future of cancer immunotherapy; one patient at a time!Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.Why Join Us?Innovative Environment: Help to pioneer advancements in cancer immunotherapy.Collaborative Culture: Be part of a diverse team dedicated to your professional growth.Global Impact: Contribute to therapies that make a lasting impact on patients globally.Role Overview:We are seeking a Clinical Trial Manager (CTM) to support our U.S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company SOPs. In this role, you will work closely with cross-functional teams and clinical sites to drive study execution, site engagement, and operational excellence across clinical trials. Reports to: Associate Director, Team Lead Site Operations Location: Fully Remote Salary Range: $130,000 - $150,000Basic Qualifications:Bachelor's degree in life sciences, nursing, or a related field2+ years of experience in on-site clinical monitoring and 2+ years of Clinical Trial Manager experience within the pharmaceutical or biotechnology industryStrong knowledge of ICH-GCP, FDA, EMA, and applicable clinical trial regulationsDemonstrated experience managing clinical trial sites, monitoring activities, and regulatory documentationProficiency with clinical trial systems and tools (e.g., CTMS, eTMF, Microsoft Office)Preferred Qualifications:Experience in oncology clinical trials or related therapeutic areasAdvanced ability to manage complex clinical operations processes and drive operational improvementsExperience leading training initiatives for CRAs and clinical trial sitesDemonstrated ability to drive quality, efficiency, and milestone achievement in fast-paced clinical environmentsExperience contributing to process harmonization, innovation, and continuous improvement initiativesStrong presentation, organizational, and cross-functional stakeholder management skillsIn this role you will:Partner with Clinical Operations leadership to support clinical trial execution and monitoring activities in alignment with project goalsLead site feasibility, selection, initiation, and greenlight activities for clinical trial sitesDevelop and maintain study-specific operational plans, training materials, and monitoring documentationOversee site management activities, including site engagement, regulatory submissions, and monitoring oversightReview trial progress, patient recruitment, and data quality metrics, and implement actions to support study objectivesProvide guidance and oversight to CRAs, including trip report review and training supportManage protocol and GCP deviations and contribute to continuous improvement of clinical operations processes and proceduresTravel required: up to 50% travel required, domestically and internationally.Qualified candidates will participate in a structured interview process, which includes:An initial recruiter phone screen (conducted via video)A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)A final-stage interview, which may include an in-person meeting at our U.S. Headquarters in Houston, TXWhat do we offer?At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join ImmaticsComprehensive Benefits:Competitive rates for Health, Dental, and Vision Insurance4 weeks of vacation, granted up front each year and prorated for first and last year of employment.12 company paid holidays7 days of sick time100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars100% employer-paid short- and long-Term disability coverage401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.Partially paid parental leave for eligible employees.Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.Equal Employment OpportunityWe are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.Reasonable AccommodationsWe are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at View email address on click.appcast.io AuthorizationApplicants must be authorized to work in the United States without the need for current or future sponsorship.Pre-Employment RequirementsEmployment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.