Principal Research Scientist II, Process Chemistry (Radiochemistry)

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  . Follow @abbvie on  LinkedIn, Facebook ,  Instagram ,  X and  YouTube.

Job Description

AbbVie Process Chemistry is responsible for the chemical development of AbbVie’s clinical candidates. We are seeking a Principal Research Scientist II to lead the Radiochemistry team that is responsible for labeling experimental drug candidates from preclinical through clinical development.

We are looking for a highly motivated person who can drive the development of drug candidates from early discovery to late-stage development through radiolabeling. The candidate will lead a group of scientists in the labeling of materials with tritium and 14C. The candidate will serve as the primary contact for labeling requests and as such would be responsible for developing strategies, timelines, and key activities required for radiolabeled drug substances. The candidate must be able to mentor and develop staff with experimental approaches to solve difficult scientific and technical challenges. Working with discovery, drug metabolism, analytical and chemistry colleagues, the candidate will develop productive collaborations and effectively communicate with scientific teams.

Responsibilities:

• The candidate will lead activities associated with labeling and characterization for new drug substances.
  • Lead the design and execution of labeling strategies.
  • Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management. Mentor staff in troubleshooting strategic and experimental issues.
  • Author and review key regulatory documents, laboratory data, technical memos, standard operating procedures, and reports.
  • Collaborate to ensure successful CMC interactions with regulatory authorities.
• The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, drug metabolism scientists, formulators, and program management.  The candidate will utilize his/her expertise across disciplines to advance the pipeline.
• The candidate will encourage ideas for continuous improvement activities and initiatives within the Radiochemistry team.
• The candidate will understand, adhere, and ensure compliance with corporate standards regarding code of conduct, safety, radiosafety and GXP compliance. 

Qualifications

• BS (16+ years); MS (14+ years) or PhD (8+ years) in Chemistry or allied field, with 8+ years of previous work experience in a pharmaceutical laboratory setting.
• Experience in radiolabeling and safety. 
• Experience in managing and developing scientific leaders is required.
• The successful candidate will have a strong understanding of synthetic organic chemistry, process development, GXP compliant processes, and radiolabeling strategies to appropriately label compounds to meet the study needs.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our long-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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