Vice President, Regulatory Affairs

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline includes RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins, such as daraxonrasib, elironrasib, zoldonrasib, and RMC‑5127, all currently in clinical development.

Opportunity

The Vice President will be the head of Regulatory Science at Revolution Medicines and will report to the head of Regulatory and Quality. The position is responsible for expanding and leading a high‑functioning group that provides clinically focused global regulatory strategy.

Responsibilities

• Provide ethical and mission‑driven leadership of the Regulatory Science function, embodying and practicing the company’s mission‑driven culture.
• Provide a vision for the Regulatory Science organization and develop a plan to achieve it, scaling the function to meet the needs of an explosive pipeline in high‑unmet medical areas.
• Ensure high‑quality, well‑vetted, globally relevant regulatory research, strategies, and advice are provided to project teams, working groups, and management via Global Regulatory Leads.
• Influence decision‑making of senior leadership.
• Collaborate closely with other functional heads to ensure high‑quality, cross‑functionally sound decision‑making.
• Integrate regulatory considerations upstream into target product profiles, clinical development plans, and financial planning.
• Maintain consistency in approach (one playbook) and foster learning across staff.
• Build the Regulatory Science organization and strategize with other leaders for maximum enterprise‑wide impact.
• Lead the function and support team member career development.

Required Skills, Experience and Education

• Local to the San Francisco Bay Area or able to travel to headquarters frequently (up to 25%).
• BA/BS degree in life sciences or related disciplines.
• At least 15 years of experience in drug development regulatory affairs.
• Minimum of 10 years in regulatory leadership or executive roles.
• Significant oncology experience.
• Expertise navigating global regulatory environments in a commercial setting.
• Ability to work in a fast‑paced, demanding, highly cross‑functional environment.
• Experience scaling an organization rapidly.
• Clear understanding of the role of regulatory science in drug development and global commercialization, and comfort with ambiguity, risk, and business optimization.

Preferred Skills

• Advanced degree in life sciences for technical fluency in oncology.
• Prior senior regulatory executive experience in oncology drug development at a medium or large pharmaceutical enterprise, with an understanding of the startup environment.

Compensation & Benefits

Base pay salary range: $284,000 – $355,000 USD.

We partner this base pay with competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Equal Opportunity Employer

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.