Post-Doctoral Research Fellow - Functional Genomics

Postdoctoral Fellow Opportunity

The Talkowski Laboratory in the Center for Genomic Medicine (CGM) at Massachusetts General Hospital (MGH), Harvard Medical School, and the Broad Institute is seeking exceptional postdoctoral candidates in computational biology, bioinformatics, and/or statistical genetics. Candidates would direct collaborative research initiatives seeking to determine the functional impact of genomic variations in developmental, neuropsychiatric, and neurodegenerative disorders.

Principal duties and responsibilities include working in a unique translational genomics environment within the CGM, which seeks to integrate computational genomics, technology development, and molecular genomics methods. At the Broad Institute, these collaborative projects span the Stanley Center for Psychiatric Research, and the Program in Medical and Population Genetics. Candidates will work with cutting-edge data types like single-cell transcriptome sequencing, Hi-C studies of 3D topology, ATACseq, 4Cseq, and other datasets in iPSC-derived neurons and organoid models of neurodevelopment. They will develop systematic computational frameworks for the integration and mechanistic interpretation of large-scale genomics datasets, synthesizing multi-omics signals into coherent biological models that reveal the molecular underpinnings of disease.

The Postdoctoral Fellow will be based at MGH under the guidance and mentorship of Dr. Michael Talkowski.

Qualifications

Skills and competencies required:

• First (or co-first) author of one or more peer-reviewed scientific publications
• Excellent English verbal and written communication skills
• Able to work both independently and in a team
• Experience with commonly used bioinformatics tools and databases
• Programming skills (i.e. R, Python, C++, etc.)
• Advanced knowledge of statistical methods
• Knowledge of neurobiology is a huge plus
• Expertise in analyzing next-generation sequencing data (i.e. WGS, WES, RNAseq, ATACseq, ChIP-seq, scRNAseq etc.)

Interested applicants should submit their CV and contacts for references to: View email address on click.appcast.io, View email address on click.appcast.io, and View email address on click.appcast.io.

Please do not apply through this link.

Remote Type: Hybrid

Work Location: 185 Cambridge Street

EEO Statement: Massachusetts General Physicians Organization, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law.