Principal Biostatistician Team Lead

Join Cleveland Clinic’s Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world. As a Principal Biostatistician Team Lead, you will serve as the team leader for a collaborative group of biostatisticians, data managers, data entry personnel and programmers by providing mentorship, evaluating performance and guiding project execution. In this role, you will provide statistical expertise in the design and conduct of clinical trials and research studies, working closely with investigators and interdisciplinary teams to develop innovative approaches and strategic solutions. You will lead multiple projects or complex components of large-scale studies simultaneously, oversee statistical programming, database management and data analysis activities, and serve as the primary point of contact for assigned projects. You will also help shape departmental policies, determine resources and budget needs for statistical support, coordinate the training and development of statistical personnel, and participate in initiatives that advance the mission of the department.A caregiver in this role works days from 8:00 a.m. – 5:00 p.m. A caregiver who excels in this role will:Oversee research personnel within assigned area, ensuring orientation and training in standard operating procedures (SOPs) in compliance with sponsoring organization and external regulatory agencies as well as performance management, career development, corrective action and terminations.In collaboration with department administrative leader, responsible for leading recruitment efforts such as initial screening of biostatistical candidates, including development and assessment of technical screening tools, and making final recommendations to leadership on candidate selection.Provide statistical expertise to other biostatisticians, including the appropriate methods for study design, sample size estimation, development of instruments for data collection, randomization procedures and appropriate statistical analysis, model building techniques, graphical techniques and appropriate references for data.Maintain professional relationships, including frequent and open effective communication with internal and external constituents.Serve as a resource for departmental staff for professional development.Assist with organizing department-wide opportunities for professional growth, including seminars, training courses, and other resources.Ensure equitable distribution of workload and allocation of resources.Determine study resources/budgets for statistical activities, ensure appropriate resources to meet contractual obligations.Other duties as assigned.Minimum qualifications for the ideal future caregiver include: Master's Degree in Biostatistics, Statistics or a related field Excellent interpersonal skills, management/leadership abilitiesDemonstrated excellence in statistical methodologyExpertise in standard statistical softwareUnderstanding of database packages for optimal data extraction and utilizationDemonstrated written and verbal skillsPreferred qualifications for the ideal future caregiver include:Fifteen years as a statistician in medical research (clinical trials preferred)Physical Requirements:Ability to perform work in a stationary position for extended periodsAbility to operate a computer and other office equipmentAbility to travel throughout the hospital systemAbility to communicate and exchange accurate informationPersonal Protective Equipment:Follows standard precautions using personal protective equipment as required.Pay RangeMinimum Annual Salary: $101,900.00Maximum Annual Salary: $155,390.00The pay range displayed on this job posting reflects the anticipated range for new hires. A successful candidate’s actual compensation will be determined after taking factors into consideration such as the candidate’s work history, experience, skill set and education. The pay range displayed does not include any applicable pay practices (e.g., shift differentials, overtime, etc.). The pay range does not include the value of Cleveland Clinic’s benefits package (e.g., healthcare, dental and vision benefits, retirement savings account contributions, etc.).Job ID: 345523Employment Type: 8:00am-5:00pmJob Area: Research and DataPosted Date: 20/07/2026