Director, RDU IT Business Partner, Commercial - Alexion
$153.02k - $200.84kWHY JOIN US?
At Alexion, a division of AstraZeneca, we are driven by a shared purpose to transform the lives of people affected by rare and devastating diseases. By combining deep expertise in rare disease with the scale, science, and innovation of AstraZeneca, we are working to deliver meaningful advances for patients and families with significant unmet needs.
Join us at an exciting time as we continue to evolve how technology, data, digital capabilities, and AI support our Commercial organization. You will have the opportunity to work closely with business and technology leaders, shape solutions that enable new product launches and commercial transformation, and help turn emerging technologies into measurable outcomes for patients and the business.
Our culture is built on collaboration, innovation, and continuous learning. We encourage our people to challenge convention, explore new possibilities, and bring forward ideas that can improve how we work and how we serve patients. As part of Alexion, you will have the opportunity to make an impact in a highly specialized area of healthcare while benefiting from the capabilities and global reach of AstraZeneca.
Hybrid Policy We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and meaningful in-person collaboration. This role is based in Boston, MA, with employees expected to work from the office three days per week , creating opportunities for teams to connect, collaborate, and solve complex challenges together.
Introduction As Director, RDU IT Business Partner, US Commercial, you will serve as a senior business-facing technology partner, shaping and delivering technology, data, digital, and AI-enabled capabilities that support commercial priorities, launch readiness, commercial transformation, and improved patient outcomes.
This position is based in Boston, MA, and may require up to 20% travel.
About the Role The Director, RDU IT Business Partner, US Commercial will serve as a senior IT Business Partner for the US Commercial organization, with a defined portfolio spanning Commercial business functions, Commercial Training, Rare Disease Therapy Area teams, launch, Finance, Commercial Operations, Market Access, and enabling functions and AI-enabled transformation.
This role will build trusted relationships with senior Commercial stakeholders, shape the multi-year technology and AI roadmap for assigned business areas, lead demand prioritization, steward portfolio health, and partner across IT, Digital, Data, AI, Architecture, Cybersecurity, Privacy, Compliance, Finance, Service Delivery, and external partners to deliver measurable business outcomes.
Key Responsibilities
Serve as a senior IT Business Partner and trusted advisor for assigned US Commercial business areas, aligning technology, data, digital, and AI roadmaps to business priorities.
Build and maintain trusted relationships with senior stakeholders across US Commercial, Commercial Training, Rare Disease Therapy Area teams, launch, Finance, Commercial Operations, Market Access, and enabling functions.
Partner with business leaders to translate strategic objectives into capability roadmaps, prioritized demand, investment options, and measurable outcomes.
Steward assigned Commercial IT portfolio activities, including demand intake, prioritization, funding alignment, risks, dependencies, value realization, ServiceNow visibility, and executive reporting.
Lead disciplined business capability mapping and technology roadmap development, ensuring roadmaps reflect business strategy, process maturity, data readiness, AI opportunity, and adoption needs.
Support Market Access and GTN priorities at the portfolio level by translating key business needs into scalable, compliant technology and data-enabled solutions.
Ensure assigned commercial solutions include appropriate governance, compliance, privacy, financial controls, adoption planning, and measurable value outcomes.
Lead launch technology planning for new products, indications, and therapy area priorities with Sales, Marketing, Commercial Training, Market Access, and business operations.
Lead through influence across business, IT, data, AI, architecture, delivery, and vendor teams; coach colleagues on business partnering, AI literacy, portfolio governance, executive communication, and value realization.
AI-Ready Business Partner Responsibilities
Enable AI for the business by identifying, framing, prioritizing, and scaling high-value AI, GenAI, agentic AI, automation, analytics, and data product opportunities across US Commercial workflows.
Translate AI ideas into business-ready use cases with clear problem statements, target users, data requirements, operating model impacts, success measures, risks, and adoption requirements.
Drive AI-enabled business outcomes across commercial decision support, launch readiness, Commercial Training enablement, executive reporting, forecasting support, customer engagement, and portfolio prioritization.
Champion responsible AI adoption by partnering with Data, AI, Architecture, Cybersecurity, Privacy, Legal, Compliance, and business stakeholders to define explainability, traceability, human oversight, auditability, security, and value measurement requirements.
Move the business from AI experimentation to measurable business impact by defining baselines, success metrics, adoption targets, governance requirements, and continuous improvement loops.
Model AI-enabled business partnering by using approved AI tools and LLM-enabled workflows to improve stakeholder preparation, meeting synthesis, portfolio reporting, roadmap development, risk identification, executive communication, and follow-through.
Use AI-assisted analysis to improve demand intake, synthesize stakeholder feedback, compare requirements, identify duplicate or overlapping requests, and generate clearer business problem statements.
Apply AI to organize knowledge, transition documentation, initiative history, open risks, dependencies, decisions, and stakeholder context while validating outputs and protecting sensitive information.
Coach business and IT partners with practical, compliant AI usage patterns that improve productivity, quality, decision speed, and accountability.
Essential Qualifications
Bachelor's degree in computer science, MIS, Business, Life Sciences, Data / Analytics, or related fields.
12+ years of experience in IT, digital, data, commercial technology, or enterprise technology roles, including business partnership, portfolio ownership, solution delivery, and cross-functional leadership.
Experience working in biotech, pharmaceutical, medical device, life sciences, or another regulated industry.
Demonstrated experience as a senior IT Business Partner or technology leader supporting Commercial, Sales, Marketing, Market Access, Patient Services, Commercial Operations, Finance, or related business functions.
Strong understanding of US Commercial business processes, launch planning, sales and marketing operations, commercial operations, portfolio governance, and value realization.
Working knowledge of Market Access, GTN, commercial operations, and related financial decision-support processes.
Experience shaping or delivering data, analytics, digital, automation, AI, or technology-enabled transformation capabilities.
Experience with CRM and related commercial platforms such as Salesforce, Veeva, or other life sciences commercial technologies.
Strong understanding of data products, analytics, reporting, commercial data foundations, SDLC, Agile practices, privacy, security, quality, compliance, and regulatory expectations.
Experience managing portfolio funding, business cases, risks, dependencies, vendor engagement, and executive-level reporting.
Ability to influence senior stakeholders, simplify complexity, drive alignment, communicate technology concepts in business language, and connect technology investments to business value, patient impact, efficiency, adoption, and risk reduction.
Preferred Qualifications
Master’s degree preferred.
Experience supporting Commercial, Finance, Patient Services, Launch Excellence, Commercial Training, Market Access, or Rare Disease Therapy Area technology portfolios.
Experience with Salesforce Health Cloud, Salesforce Life Sciences Cloud, Veeva, Service Cloud, Experience Cloud, ServiceNow, Snowflake, data products, BI / analytics platforms, or AI-enabled commercial platforms.
Experience with rare disease commercial models, specialty pharmacy, patient access, payer engagement, field reimbursement, care coordination, or high-touch business-facing environments.
Experience leading governance forums, executive portfolio reviews, vendor partnerships, product-oriented operating models, transformation programs, adoption plans, and value-realization plans.
Familiarity with responsible AI principles, including explainability, traceability, human oversight, auditability, privacy, compliance, risk management, and adoption of governance.
Strong leadership presence with the ability to balance strategic thinking, operational discipline, stakeholder empathy, and execution focus.
SO, WHAT’S NEXT?
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.
Where can I find out more?
- Explore what we’re building:
- Stay connected and see our impact in action:
Apply today to shape the future of AI-powered rare disease care! Alexion is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. Alexion is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing View email address on careers.astrazeneca.com .
#LI-Hybrid The annual base pay for this position ranges from $153,018.40 - $200,836.65 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.
Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Date Posted
16-Oct-2026Closing Date
22-Oct-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
$153.02k - $229.53k
Role OverviewAs Director, IT Business Partner - Global Medical Affairs, you will serve... ...in the Rare Disease Unit (RDU). In this strategic role,... ...functional initiatives with Commercial, R&D, and enabling functions... ...across AstraZeneca/Alexion IT, the broader RDU, and external...CommercialFull timeTemporary work$195k - $225k
...aspire to alter the course of lives.The IT Business Relationship Director is the senior technology leader... ...realization. Salesforce is the key commercial platform for both Epilepsy and OSA,... ...Salesforce to the role. The Director will partner closely with the Salesforce Center...CommercialFull timePart timeLocal areaRemote workWorldwide- ...thought leader and confidant to the business and internal People & Organization... ...human resources service delivery. The Director - People Business Partner will report into the Senior... ...relationship and stakeholder management.Commercial insight of the organization (including...CommercialTemporary workLocal area
$125k - $130k
...hazardous waste and pollution treatment leader. It offers a full spectrum of water, waste,... ...water and wastewater treatment, commercial and hazardous waste collection and disposal... ...Integrated in the Technical expertise & Business support team, the Senior Technical Manager...CommercialFor subcontractor$107k - $179k
...uniqueness and an ever-forward mindset. Job Summary: Partners with Business Unit, Entity, or workgroup leadership to execute People Practices... ..., life sciences, healthcare, higher education and commercial markets. Founded in 1990, DPR is a great story of entrepreneurial...CommercialDaily paidPermanent employmentFull timeFor contractorsWork experience placementRelocationRelocation packageMonday to Friday$183k - $200k
...Amylyx Pharmaceuticals, Inc.Posted: 2026-10-18Associate Director, IT Commercial and Medical AffairsApplicationsCambridge, MAAmylyx has an... ...Commercial and Medical. Reporting to the Director, IT Commercial Business Partner, you’ll partner across Commercial, Medical Affairs,...CommercialLocal areaRemote work1 day per week$90k - $120k
...externally-facing generalist to help drive commercialization on our flagship product — Cassie.... ...this role, you’ll be responsible for the business growth of the Cassie product lines and... ...margins, etc.)Coordinate with customers, partners, investors, vendors, and domain experts...CommercialFull time$110k - $188.75k
Technical/Business Program Manager, Vice President / SSIMWhat you will... ...’s, including: contracts and commercials, scope and solution, project... ...involved is fully informed.Partner across technology teams such... ...StatementJob Application Disclosure:It is unlawful in Massachusetts...CommercialFull timeTemporary workFlexible hoursShift work$130k - $160k
...form of ownership—it’s our approach to business and relationships. We know that supporting... ...value for clients while balancing commercial, technical and operational considerations... ...management. Across Investor Services and Capital Partners, we work with an enviable roster of...CommercialFull timeLocal area$200k - $235k
.... Experience #LifeatRealChem.Director, Technical Product OperationsRole... ...), delivered to clients as a commercial product, engineered to be SOC... ...for the platform — partnering with Information Security and... ...PartnershipLead, and mentor the external IT / platform engineering team,...CommercialWork experience placementWork at officeLocal areaRemote work2 days per week- ...manufacturing, and product deployment.You'll partner closely with engineering leadership,... ...'s degree in Engineering, Robotics, or Business Administration. Experience working within... ...products from prototype through commercial deployment. Familiarity with robotic systems...CommercialFull timeContract work
$166k - $220k
...the expertise, technology, and business model of the 21st century’s... ...communication across critical commercial and defense mission sets. You... ...working with Indo-Pacific partner nationsExperience with Confluence... ...from one of our recruiters, it will only come from an @...CommercialPermanent employmentFull timeContract workTemporary workWork experience placementImmediate start$166k - $220k
...the expertise, technology, and business model of the 21st century’s... ...survey and exploration data for commercial and government customers... ...deliverables, and timelines. Partner with Field Operations to identify... ...from one of our recruiters, it will only come from an @...CommercialFull timeContract workWork experience placementImmediate startWorldwide- ..., architecture, finance, and business stakeholders, this leader will... ...strategic technology partners including AWS, Databricks, Snowflake... ...enterprise priorities, timelines, commercial objectives, and quality... ...experience.In-depth knowledge of IT concepts, strategies and...CommercialLocal areaRemote workVisa sponsorshipWork visaShift work
$128.9k - $193.3k
...with cross-functional teams that review and support the contract drafting processWork closely with global accounting, finance, and commercial organizations to support internal and external financial revenue reporting requirementsPartner with the SEC Reporting team to...CommercialFull timeContract workSummer workWork at officeLocal areaRemote workFlexible hours2 days per week$165.8k - $224.2k
Overview Join the Alnylam Commercial Data and Analytics team and help... ...deployed decisions with measurable business impact. As part of Customer... ...with technical and business partners to accelerate commercial... ...rely on every day.As Associate Director, Data Steward, you will contribute...CommercialFull timeTemporary workLocal areaFlexible hours$144k - $241k
...creation and capture, through customer and commercial strategies, digital products and... ...engineers, and architects. Our team balances business strategy, technology, creativity, and ongoing... ...biggest problems that affect customers, partners, constituents, and the...CommercialLocal area$184k - $218k
Associate Director, IT Application Management (Market Access & Patient... ...is an independent, commercial-stage biopharmaceutical company... ...technology lead and strategic partner for the Market Access and Patient... .... Working across business, enterprise IT, data and analytics...CommercialContract workTemporary workFlexible hours$136k - $162k
...at the heart of our R&D and commercialization efforts to reduce the... ...Reporting will report to the Director, Technical Accounting & Financial... ...Forms 10-K and 10-Q, while partnering closely with FP&A,... ...accounting implications of key business decisions are appropriately...Commercial$194k - $291k
...of delivery (e.g. managing internal and partner teams), project reportingTrack and manage... ...renewalBuild and deliver executive business reviews that connect Amplitude usage to... ...and for connecting customer outcomes to commercial value. Prescriptive Customer Guidance: Sets...CommercialWork at officeRemote workHome office$134.5k - $265.1k
Position Summary Join Deloitte’s HR Business Process as a Service (BPaaS) Solution Hub, where you will turn complex client needs into commercially sound, delivery-ready HR managed-services solutions. As a Manager, HR Solution Architect, you will combine operational...CommercialLocal areaVisa sponsorship$184.6k - $277k
...DescriptionGeneral/Position SummaryThe Director, Manufacturing Process &... ...from development through commercialization and post-approval lifecycle... ..., Regulatory, and external partners, the Director ensures... ...regulatory expectations, and business priorities.Key Duties & ResponsibilitiesStrategic...CommercialFull timeSummer workRemote workFlexible hours2 days per week$120k - $180k
...empower people in all aspects of their business. Our people make all the difference in... ...here, work with engineering to deliver it, and partner with sales, marketing, customer success... ...commerce/CPQ systems Experience with SaaS commercial systems such as self-serve purchasing,...CommercialFull timeWork at officeLocal areaImmediate startVisa sponsorshipFlexible hours2 days per week3 days per week$160k - $270k
...customers, or bringing it to market through our partner ecosystem, your work directly drives... ...and roadmap context to customers, while commercial aspects like QBRs, CSAT/NPS, upsells,... ...CIOs, CTOs, enterprise architects, and business leaders.Orchestration & Collaboration: Coordinate...CommercialFull timeFlexible hoursShift work$181.5k - $278.3k
....We are seeking an Associate Director, MLOps Lead to join our Machine... ...deployment needs across the business units. Successfully manage... ...Cross-Functional Collaboration: Partner with leaders across machine... ...tools against best-in-class commercial and open-source alternatives...CommercialTemporary workRelocation package$148.5k - $214.5k
Job title: Associate Director, Digital Marketing, Rare HematologyLocation... ...across the ecosystem, partnering with brand, GTMC, cross-... ...alignment to brand strategy and business objectives.Lead the... ...recommendations for the broader WAYRILZ commercial team.Consistently optimize...CommercialFull time- ...externally-facing generalist to help drive commercialization on our flagship product — Cassie.... ...this role, you’ll be responsible for the business growth of the Cassie product lines and... ...margins, etc.) Coordinate with customers, partners, investors, vendors, and domain experts...Commercial
- ...role focused on translating customer and business requirements into clear engineering... ...Support execution of engineering programs for commercial and government customers, from... ...with design and customer requirements Partner with operations to align engineering execution...CommercialContract workShift work
$125k - $150k
Associate Director / Director, Data Strategy & MeasurementLocation:... ...all positions at Acceleration Partners. Some travel is required for... ...measurement, AI-enabled insights and commercial growth. The Director will... ...their marketing and business data ecosystem, develop measurement...CommercialSummer holidayRemote workWork from home$170.4k - $255.6k
...DescriptionGeneral SummaryThe Associate Director, External Innovation reports into the Executive... ...for conducting scientific, clinical and commercial analysis, monitoring company/technology... ...landscaping projects & external business opportunities in the pharmaceutical, biotechnology...CommercialFull timeSummer workRemote workFlexible hours2 days per week
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Director, RDU IT Business Partner, Commercial - Alexion. Be the first to apply!
- customer business manager Boston, MA
- business manager Boston, MA
- director business analytics Boston, MA
- manager business intelligence Boston, MA
- business director Boston, MA
- business affairs manager Boston, MA
- business planning manager Boston, MA
- director enterprise solutions Boston, MA
- IT business relationship manager Boston, MA
- manager enterprise sales Boston, MA


