Principal Architect (Applied AI + SaaS) - Office of the CTO

About the company Biorce is a pioneering Healthtech company dedicated to revolutionizing drug development through the power of AI. We are passionate about accelerating medical advancements and improving patient outcomes. Our team comprises seasoned clinical research professionals, data scientists, and AI experts, working collaboratively to bridge the gap between cutting-edge technology and real-world clinical needs. With an unwavering commitment to revolutionize healthcare, we envision a world where all patients benefit from accelerated and cost-effective access to treatments. Biorce is poised to redefine the landscape of healthcare, shaping a future where innovation and accessibility converge for the betterment of humanity. About the role Following our successful expansion into the U.S. and continued growth across Europe, we are seeking a Staff/Principal Solutions Architect to help drive our Engineering function from our Austin / Barcelona hub. Reporting directly to our Head of Engineering, this person will play a critical role in shaping the architecture of our multi-tenant SaaS platform and the applied-AI layer that sets it apart, making sure both scale safely in a regulated, audited environment. You will be our most senior architecture voice across the product engineering vertical: the person who turns ambitious ideas into systems that are reliable, secure, and ready for a hard compliance gate. Who we're looking for A senior distributed-systems and SaaS architect who has gone deep on applied AI over the last few years — someone who treats agents and LLM features as production services with contracts, evaluations, and failure modes, not as experiments. You are equally comfortable designing multi-tenant backend microservices and reasoning about retrieval pipelines, agent safety, and inference cost. You influence without needing to own everything, you still write code, and you design for auditability from day one. This person should be able to own the end-to-end architecture of our application and AI layers and raise the technical bar for the whole team. Key responsibilities Own architecture across the product domains: service decomposition, contracts, and clear boundaries. Architect the applied-AI layer, agent orchestration, retrieval-augmented generation, and tool-use safety. Establish LLM evaluation, observability, and cost-modelling practices that hold up in production. Set guardrails for multi-tenancy, data residency, and immutable audit that future infra and data hires build on. Write architecture decision records and standards that peers want to follow. Partner with platform, research, and scientific stakeholders to ship fast without compromising compliance. Must-haves 10+ years building software, with 4+ as a named architect or tech lead on systems at meaningful scale. Strong SaaS platform fundamentals: multi-tenant authorization and entitlements, API gateway and backend-for-frontend patterns, event-driven design, and a database-per-service mindset. Security reasoning for cloud-native systems, including the OWASP Top 10 for SaaS and LLM Applications and agent permission scoping. Delivery experience in a regulated or audited environment (health, fintech, or government): audit trails, data integrity, and designing for a hard compliance gate. Still hands-on: you prototype the risky parts yourself rather than only producing diagrams. Nice-to-haves Recent, hands-on applied-AI work shipped to production: RAG and vector databases, and agentic or multi-agent orchestration (e.g. LangGraph, Semantic Kernel, CrewAI, or equivalent). LLM evaluation, observability, and per-conversation cost modelling. Life sciences or clinical trials background (FDA 21 CFR Part 11, GxP, eTMF). Working fluency with Kubernetes and data-residency design. Experience with knowledge graphs and semantic/embedding-based retrieval at scale. Track record influencing across organizational boundaries without formal authority. Why Join Us? A dynamic work environment with an international team, where collaboration and diversity thrive. Work alongside top talent, united by a shared purpose and committed to making a real impact. Comprehensive private health coverage to ensure your physical and mental well-being. Hybrid work model offering flexibility to balance your professional and personal life. Company events to celebrate achievements and enjoy time together. Get equipped with a MacBook to enhance your productivity and work experience. Our office is pet-friendly! You’ll likely be greeted by a few wagging tails upon arrival. #J-18808-Ljbffr Biorce