Manager, Clinical Business Operations

Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well‑funded, Nasdaq‑listed biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing. Our antibody programs are designed to overcome limitations of existing therapies by targeting well‑established mechanisms of action and incorporating advanced antibody engineering to optimize half‑life and other properties. Role Summary We are seeking a Manager, Clinical Business Operations to join the Clinical Operations team at Apogee and focus on a specific therapeutic area. The role is responsible for providing project planning support for our dermatology or respiratory clinical programs. This self‑starter will organize projects effectively in a fast‑paced setting and apply clinical operations and project management expertise to deliver innovative medicine to patients. Key Responsibilities Maintain and communicate a current overview of Clinical Operations program status and issues. Work with Clinical Operations team members to identify resource constraints, risks, and conflicts that could impact the team’s ability to deliver according to plans. Provide project‑management support for one or more clinical programs, including building and maintaining the clinical study plans by interfacing with external partners. Collaborate closely with the cross‑functional Program Management team to ensure integration of Clinical Operations activities into overall program plans and monitor project deliverables. Work collaboratively to create project planning guidelines and playbooks for use across projects. Establish and track key performance indicators (KPIs) and metrics to evaluate performance and identify areas for improvement. Document, standardize and publish department processes and procedures while identifying potential operating efficiencies. Prepare reports, presentations, and other deliverables related to project updates, process improvements, or other business initiatives. Participate in Work Order and Change Order negotiation, review, and approval. Submit purchase orders in NetSuite, review and approve vendor revenue recognition, accruals, and invoices. Assist with tracking outsourced activities as needed. Ideal Candidate Bachelor’s degree in science. 10+ years of experience in biotech or pharmaceutical industry. 3+ years of Clinical Operations experience. Experience working with clinical‑stage candidates across all phases of clinical development (Ph I‑Ph III). Extensive knowledge of Smartsheet and/or Microsoft Project. Confident, proactive, and highly organized with meticulous attention to detail. Ability to multi‑task and keep pace with a fast‑moving organization. Successfully exhibit Apogee’s C.O.R.E. values: Caring, Original, Resilient, and Egoless. Ability and willingness to travel up to 15% for company all‑hands meetings. The anticipated salary range for this role is $145,000 - $160,000, depending on experience, education, and geography. What We Offer A culture grounded in our C.O.R.E. values: Caring, Original, Resilient, and Egoless. Opportunity to work in a fast‑paced, highly dynamic environment where you can shape culture, wear multiple hats, and learn quickly. Market‑competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, and health, welfare, and retirement benefits. Competitive time off, including three weeks PTO, two one‑week company‑wide shutdowns a year, and dedicated paid sick leave. Commitment to your professional growth and access to resources for further development. Regular all‑team, in‑person meetings to build relationships and solve problems. Apogee participates in E‑Verify for all U‑S. applicants. Please review the E‑Verify poster for details. Apogee is an Equal‑Opportunity Employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law. #J-18808-Ljbffr Apogee Therapeutics