Pediatrics Cytogenetic Lab Specialist I
University of Iowa
Cytogenetic Lab Specialist I
The Shivanand R Patil Cytogenetics and Molecular lab, within the Stead Family Department of Pediatrics, is seeking a cytogenetic lab specialist I. The lab utilizes molecular and cytogenetic techniques, including chromosome analysis, fluorescence in situ hybridization (FISH) chromosomal microarray (CMA), and genome sequencing for diagnosis or treatment in cancer and constitutional genetic disorders. In this role, the laboratory technician will perform components of cytogenetic and molecular studies according to established laboratory protocols and work to maintain and improve the clinical testing environment, capabilities and quality of data in the laboratory. This position will perform cytogenetic and/or molecular studies from biological specimens for the diagnosis, prevention or treatment of certain disorders under supervision.
Position Responsibilities:
- Performs cell culture on varieties of tissues received for chromosome analysis according to established protocols.
- Processes cultured cells and prepares slides according to laboratory protocol of chromosome spreads.
- Stains slides utilizing a variety of techniques including G-banding and fluorescent in-situ hybridization for chromosome identification.
- Prepares microscope analysis of metaphases and prometaphase chromosomes for diagnostic purposes.
- Prepares digitized karyotypes using correct International System for Human Cytogenetic Nomenclature (ISCN).
- Performs analysis of fluorescence in situ hybridization (FISH) studies for clinical diagnostic and prognostic purposes
- Performs chromosomal microarray (CMA) or NGS bench work (wet lab) and initial data analysis.
- Maintains accurate and legible records of all lab results and procedures, and accurately interprets and records test results.
- Participates in lab section meetings with others to discuss quality testing, workflow, efficiency strategies, problematic areas, and laboratory improvement.
- Performs additional tasks as may be assigned by section coordinator or laboratory supervisor such as maintaining records of inventory and ensuring timely ordering of reagents.
- Communicates any problems with equipment to the laboratory supervisor.
- Complies with the appropriate health and safety regulations and work rules.
- Attends and participates in laboratory staff meetings and continuing education programs.
- Demonstrates respect for all members of the University community in the course of performing one's duties and in response to administrators, supervisors, coworkers, and customers.
- Represents the interests of the University and of unit leadership in the use of resources to meet service and productivity demands within unit goals and budgets; strive to promote continual process and quality improvement.
- Seeks opportunities to enhance one's own professional knowledge, skills, and abilities as they relate to one's current position and/or prepares for potential future roles and overall career development.
- May perform functional supervision over support staff.
Education Requirements:
- A bachelor's degree in biological sciences, Medical Technology, Clinical Laboratory Sciences, a related scientific discipline, or an equivalent combination of education and experience.
- ASCP certification in Cytogenetics or Molecular Biology.
Experience Requirements:
- Must have the visual acuity and analytical skills to distinguish fine detail.
- Must be able to function at the required capacity to meet caseload and turnaround times, including the ability to set priorities and to optimize the best use of time.
- Ability to work in a fast-paced environment.
- Demonstrated excellent written and verbal communication skills.
Highly Desired Qualifications:
- Demonstrated experience in tissue culture techniques for human and other mammalian cells.
- Demonstrated technical skills in cytogenetic molecular biology as well as preparing slides from tissue for examination.
- Familiarity with handling and operating digital imaging systems with various software and programs.
- Familiarity with techniques in FISH and CMA
- Familiarity with high throughput DNA sequencing (also called next generation sequencing)
Desired Qualifications:
- Participation in scholarly activities.
Position and Application details:
- In order to be considered for an interview, applicants must upload the following documents and mark them as a "Relevant File" to the submission:
- Resume
- Cover Letter
Job openings are posted for a minimum of 14 calendar days and may be removed from posting and filled any time after the original posting period has ended.
Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification. Up to 5 professional references will be requested at a later step in the recruitment process.
For additional questions, please contact View email address on click.appcast.io
This position is not eligible for university sponsorship for employment authorization.
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