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OR RN

PRN Healthcare Services

Smiling Faces. Beautiful Places.


South Carolina is the perfect place for traveling medical professionals to live the life they've always dreamed of. In the summer, South Carolina has fantastic beaches with surf, sun, and sand for you to enjoy. But that's not all, there's also fantastic shopping, great food, historic sites, and great outdoor fun. This is all waiting for you in South Carolina.

Why PRN Healthcare?


Your adventure starts here with PRN Healthcare!


Take control of your career with a travel contract or local contract. Our recruiters are trained matchmakers. By building authentic relationships, we get to know your wants, needs, and everything in between when it comes to your next contract. Armed with this knowledge, we curate opportunities that check your boxes. At PRN our mission is to put our travelers first, make a difference in our communities, and provide exceptional client satisfaction. See why so many are making PRN Healthcare their preferred healthcare staffing company:



  • Top-tier access to premium healthcare jobs nationwide
  • Decades of strong relationships with hospitals and facilities
  • A robust credentialing team that helps locate and pay for pre-employment labs and testing
  • Reliable and consistent support staff who ensure you have an exceptional experience from start to finish
  • Real people are always here to answer your questions and concerns 24/7
  • We make it easy to travel with your fur baby, family, or friend
At PRN Healthcare, our people are our most important asset. We prioritize taking care of the healthcare professionals who spend their careers taking care of patients in our communities. Here are some benefits of working with PRN:
  • Competitive pay
  • Generous housing stipends
  • Medical, Dental, Vision
  • 401(k) with company match
  • Refer-a-friend bonus
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the OR RN in Charleston, SC vacancy
  •  ...Description RN- Registered Nurse - OR- Operating Room Specialty : OR- Operating Room Location : Charleston,SC,29425 Start Date : 2026-06-29 End Date : 2026-09-26 Duration : 13 Week Shift : 3x12 Job Description... 
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    Alliance Medical Staffing

    Charleston, SC
    3 days ago
  • $1,887.62 per week

     ...Job Title : Registered Nurse (RN) - Operating Room (OR) Location : Charleston, SC Start Date : 07/13/2026 Duration : 13 weeks Shift : 3x12 Days Hours/Week: 36 Estimated Gross Pay Per Week Up To: $1887.62 (includes up to $1167.62 travel stipend... 
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    ATC Healthcare

    Charleston, SC
    3 days ago
  • $2,166 per week

     ...ALOIS Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. Job Description & Requirements ~ Specialty: OR - Operating Room ~ Discipline: RN ~ Start Date: 07/13/2026 ~ Duration: 13 weeks... 
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    ALOIS Healthcare

    Charleston, SC
    5 days ago
  • $1,993 per week

     ...Trustaff is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. Job Description & Requirements ~ Specialty: OR - Operating Room ~ Discipline: RN ~ Start Date: 07/06/2026 ~ Duration: 13 weeks ~40... 
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    trustaff

    Charleston, SC
    3 days ago
  • $1,694.88 per week

     ...Registered Nurse that is licensed in SC to work in the specialty area of OR - Operating Room. (Compact license acceptable) This is a 1...  ...Requirements Include: ~2 years of recent experience as a RN ~1 year of recent experience specializing in OR - Operating... 
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    TRS Healthcare

    Charleston, SC
    23 hours ago
  • $2,270 per week

     ...Vibra Travels is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. Job Description & Requirements Specialty: OR - Operating Room Discipline: RN Duration: 13 weeks 40 hoursper week Shift: 8 hours, days Employment Type:... 
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    Vibra Travels

    Charleston, SC
    3 days ago
  •  ...Job Description Job Description Requirements: Experience: Minimum 2 years preferred (first-time OR RNs accepted) Licenses: SC RN license or Multi-State Compact RN license Certifications: BLS required; Radiation Badge provided by agency Trauma Level: Experience... 

    Lancesoft INC

    Charleston, SC
    more than 2 months ago
  • $46 - $48 per hour

     ...American Medical Staffing is seeking a local contract nurse RN OR - Operating Room for a local contract nursing job in Charleston, South Carolina. Job Description & Requirements ~ Specialty: OR - Operating Room ~ Discipline: RN ~ Start Date: 07/06/2026 ~ Duration... 
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    American Medical Staffing

    Charleston, SC
    1 hour ago
  •  ...Job Description Summary Job Description Summary The Nurse Practitioner or Physician Assistant covering neonatal and newborn services reports to the Neonatal APP Lead. The Nurse Practitioner or Physician Assistant manages a case load of neonatal patients in consultation... 
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    MUSC

    Charleston, SC
    -5
  •  ...Job Description Summary The successful applicant will be a Nurse Practitioner or Physician Assistant interested in working full-time in the care of patients with kidney disease in our ambulatory clinics and our DCI clinics (Dialysis Clinic, Inc). The ideal candidate will... 
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    Medical University of South Carolina

    Charleston, SC
    3 days ago
  •  ...the senior healthcare landscape, you're in the right place—and we look forward to working with you. Position: Nurse Practitioner or Physician Assistant We are seeking a compassionate and skilled Nurse Practitioner or Physician Assistant to join our healthcare team... 
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    AllyAlign Health

    Charleston, SC
    5 days ago
  •  ...(Only QUALIFIED Healthcare Professionals accepted) Nurse Practitioner or Physician Assistant - If you are passionate about providing exceptional patient care and thrive in a collaborative healthcare environment, we want you on our team. As a leading outpatient physical... 

    National Coalition of Healthcare Recruiters

    Charleston, SC
    4 days ago
  • $1,945 per month

     ...Client Name MUSC Health Charleston Job Type Travel Offering Nursing Profession RN Specialty OR Job ID 36908521 Job Title RN - OR Weekly Pay $1945.0 Shift Details Shift... 
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    Mission Hospital

    Charleston, SC
    23 hours ago
  • Job Title Details Job Type Local Profession RN Specialty OR Shift Details Shift 12H Days Job Order Details Start Date 07/13/2026 End Date 10/17/2026 Duration 13 Week(s) Client Details City Charleston State SC
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    Wellspring Nurse Source

    Charleston, SC
    4 days ago
  • $2,255 per month

     ...Details Client Name MUSC - Charleston Job Type Travel Offering Nursing Profession RN Specialty OR Job ID 36907518 Weekly Pay $2255.0 Shift Details Shift 06:30 AM - 05:00 PM... 
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    Carilion Roanoke Memorial Hospital

    Charleston, SC
    1 day ago
  •  ...Our Client is currently seeking OR for positions in Charleston, SC for a 3×12 Days shift. The ideal candidate will possess a current SC...  ...Requirements Shift 3×12 Days • Current Resume • RN License • Current BLS and/or ACLS and/or Specialty... 
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    Specialty Professional Services, Corp.

    Charleston, SC
    2 days ago
  •  ...Rn - Or Pride-Health offers eligible employees comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance... 
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    PRIDE Health

    Charleston, SC
    5 days ago
  • $1,900 per week

     ...RN - Operating Room OR Registered Nurse - Health Advocates Network is urgently hiring Operating Room OR RNs with at least 2 years of recent experience! IMMEDIATE STARTS! ~ Travel packages: $ 1,900.00 weekly ~ Shift: 12- hour DAY shifts available... 
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    HAN Staff

    Charleston, SC
    3 days ago
  • $1,980 per month

     ...MUSC Health University Medical Center Job Type Travel Offering Nursing Profession RN Specialty OR Job ID 36907031 Job Title RN - OR Weekly Pay $1980.0 Shift Details Shift... 
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    Mission Hospital Asheville

    Charleston, SC
    4 days ago
  • $1,750.5 per month

     ...Medical University of South Carolina Job Type Travel Offering Nursing Profession RN Specialty OR Job ID 37250241 Job Title RN - OR Weekly Pay $1750.5 Shift Details Shift... 
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    UofL Health - Jewish Hospital

    Charleston, SC
    23 hours ago
  •  ...Travel RN Opportunity Meda Health is looking for an OR RN to work a travel assignment in an acute care hospital setting. Must have at least two years of experience, state licensure and BLS/ACLS (at minimum). Competitive and Transparent Pay We value your expertise... 

    Meda Health

    Charleston, SC
    23 hours ago
  •  ...RN - OR - Operating Room Are you an experienced OR RN looking for your next exciting travel assignment, or are you ready to start your travel healthcare career? At Voca, we offer an unmatched experience for healthcare professionals with a travel-first culture that prioritizes... 
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    Voca Healthcare

    Charleston, SC
    3 days ago
  • $1,280 - $1,751 per week

     ...RN - OR Weekly Pay: $1280 - $1751 Shift Details: 12 hour days Start Date: 07/13/2026 End Date: 10/12/2026 Duration: 13 Week(s) City: Charleston State: SC *Estimated pay and benefits package based on pay range over last 36 months. Exact pay and benefits... 
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    TGL Medstaff

    Charleston, SC
    2 days ago
  • $1,596 - $1,773 per week

     ...demeanor and professional appearance. Technical Skills - the ability to grasp, push/pull, and move while assisting with procedures or operating departmental equipment. Cognitive Demands - capable of managing frequent interactions with the public and customers... 
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    CrossMed Healthcare

    Charleston, SC
    4 days ago
  •  ...OR RN Opportunity In Charleston, South Carolina Zack Group is currently seeking OR RNs for positions in Charleston, South Carolina. The ideal candidate will possess a current state or equivalent compact license. This is a 3x12 Days, 07:00:00-19:00:00, 12.00-3 position... 
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    Zack Group Healthcare Staffing

    Charleston, SC
    5 days ago
  • $2,882 per month

     ...Client Name Roper Saint Francis (Parent) Job Type Travel Offering Nursing Profession RN Specialty OR Job ID 18609551 Job Title RN - OR Weekly Pay $2882.0 Shift Details Shift... 
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    OU Health (Parent)

    Charleston, SC
    3 days ago
  •  ...RN - OR Operating Room Nurses Responsible for planning, executing, directing and evaluating, direct and indirect nursing care given to the surgical patient. The nursing activities may include preoperative, intra-operative and postoperative evaluation. Operating Room... 

    Care Career

    Charleston, SC
    5 days ago
  • $1,567 per month

     ...Client Name MUSC University Health Job Type Travel Offering Nursing Profession RN Specialty OR Job ID 37247621 Job Title RN - OR Weekly Pay $1567.0 Shift Details Shift... 
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    Springfield Memorial Hospital - AYA

    Charleston, SC
    11 hours ago
  •  ...(10:30 AM-11:00 PM) Location: Charleston, SC Length: 13 weeks Weekly Hours: 36.0 Beds: 467 At least 2+ years' experience Either an Associate of Science or Bachelor of Science in Nursing (ASN or BSN) Registered Nurse (RN) licensed Valid SC license... 
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    Triage Staffing

    Charleston, SC
    23 hours ago
  •  ...Operating Room Registered Nurse (OR RN) Location: South Carolina Assignment Duration: This is a 13-week contract position. Schedule: 4x10-hour shifts, Days (6:30 AM - 5:00 PM), with holiday rotation and one weekend working shift every 4 weeks. On-call required... 
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    ARMS Staffing

    Charleston, SC
    23 hours ago

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