Clinical Pharmacology Lead (Manager)

Pfizer seeks a Clinical Pharmacology Lead (Manager) to direct clinical pharmacology strategy and model-informed drug development efforts for Internal Medicine portfolio projects. The role involves designing pharmacokinetic/pharmacodynamic analyses, overseeing clinical development plans, and providing regulatory expertise across multifunctional teams.

Responsibilities

• Serve as clinical pharmacology representative on clinical and development teams
• Design and execute clinical pharmacology plans incorporating best practices and MIDD approaches
• Plan and oversee project-level activities including PK/PD analyses and dose-finding strategies
• Author protocols, oversee clinical phases, and contribute to regulatory submissions
• Stay current with scientific literature, regulatory guidelines, and publish findings

Requirements

• M.D./Ph.D. or equivalent training in pharmacokinetics, pharmacometrics, or clinical pharmacology
• PharmD with 2+ years of pharmaceutical industry experience alternatively
• Expertise in mechanistic PK/PD modeling, population modeling, and clinical trial simulations
• Proficiency with quantitative tools such as NONMEM and R
• Excellent written and verbal communication and presentation skills
• Demonstrated leadership experience with ability to influence cross-functional peers
• Capacity to work across global time zones in hybrid arrangement

Compensation: $106,000-$176,600 base salary, plus 15% bonus target and long-term incentive eligibility