Postdoctoral Fellow - Large Molecule Discovery (LMD)
BioSpace
Postdoctoral Fellow - Large Molecule Discovery (LMD) Join to apply for the Postdoctoral Fellow - Large Molecule Discovery (LMD) role at BioSpace Postdoctoral Fellow - Large Molecule Discovery (LMD) 1 week ago Be among the first 25 applicants Join to apply for the Postdoctoral Fellow - Large Molecule Discovery (LMD) role at BioSpace Get AI-powered advice on this job and more exclusive features. Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Postdoctoral Fellow - Large Molecule Discovery What You Will Do Lets do this. Lets change the world. In this vital role you will conduct & contribute to the design and execution of research projects, the analysis of data, and the preparation of scientific manuscripts to assist Amgen's pipeline. Develop novel and biopharmaceutical industry leading peptide, protein, antibody and multi-specific antibody MS and MS/MS analytical techniques. Create automated sample handling, digestion, data processing and computational workflows that will accelerate Amgens therapeutic pipeline. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications. Basic Qualifications A doctorate degree (PhD) in biochemistry or analytical chemistry. A working understanding of mass spectrometry, and its application for peptide and protein analytics in a dynamic research environment. A working understanding of Python programming. A working understanding of molecular dynamics packages. Preferred Qualifications A doctorate PhD in biochemistry or analytical chemistry, with a focus on mass spectrometry analytical and computational methods. A deep understanding of mass spectrometric, intact and sub-unit protein RPLC-MS analyses, bottom-up RPLC-MS/MS approaches, other protein structural analytical methods and techniques for post translational modifications (PTMs) and high order structure determination and inference will be advantageous. Extensive experience with HDX-MS, FPOP, X-linking or other covalent labelling techniques will be advantageous. A good understanding of protein digestion methods, sample handling, MS and LC automation and application is highly desired. Experience with Agilent LC-ToF/Q-ToF MS, Thermo Orbitrap QExactive and Fusion Tribrid MS and Waters Q-ToF instruments are highly desired. Experience handling and analyzing large-scale MS, MS(MS) and/or proteomics datasets using statistical and machine learning techniques is desirable A good working knowledge and experience with scientific computing libraries such as NumPy, pandas, SciPy, or scikit-learn will be advantageous. A working understanding of molecular dynamics, such as Molecular Operating Environment (MOE) and/or Schrodinger is preferred. Familiarity with running software in cloud computing environments is highly preferred. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Seniority level Seniority level Internship Employment type Employment type Full-time Job function Job function Research, Analyst, and Information Technology Industries Internet News Referrals increase your chances of interviewing at BioSpace by 2x Sign in to set job alerts for “Postdoctoral Researcher” roles. Postdoctoral Fellow - Large Molecule Discovery (LMD) Postdoctoral Fellow/Psychological Assistant Research Scientist, Pathology - Cell Therapy Research Engineer - Audio Driven Facial Animation Santa Monica, CA $175,000.00-$210,000.00 2 days ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI. #J-18808-Ljbffr BioSpace
- ...expression and cell line engineering to support the discovery and optimization of large-molecule therapeutics, including antibodies, bispecific, and next... ...Doctorate degree- PhD, PharmD or MD with relevant postdoctoral experience OR Master’s degree and 3 years of cell biology...For PostDocFlexible hours
$209.66k - $283.65k
...patients while transforming your career.Director - PKDM - Small Molecule Portfolio Strategy & LeadershipWhat you will doLet’s do this.... ...the advancement of small molecule programs from candidate discovery through clinical development and regulatory submission. You will...For PostDocFull timeFlexible hours$140.12k - $189.58k
...patients while transforming your career.Principal Scientist - Lead Discovery and Targeted Protein Degradation BiochemistryWhat you will... ...to support the discovery and advancement of novel small-molecule therapeutics.The successful candidate will:Lead protein expression...SuggestedFull timeFlexible hours$100 per hour
...while earning up to $100+/hour, fully remote, with flexible weekly hours. No AI experience required Role Overview Help fine-tune large language models (like ChatGPT) using your chemistry knowledge. You’ll design problems, check how well AI solves them, and work with...For PostDocContract workRemote workFlexible hours$182.47k - $246.87k
...during clinical development of therapeutic molecules.Define and execute workflows for... ...analyzing multi-modal, multi-dimensional, and large-scale biological data.Prior experience... ...how computational biology can drive drug discovery and development in these areasAbility to...For PostDocFull timeFlexible hours$127.12k - $171.99k
...GenomicsWhat you will doThe Functional Genomics group within Target Discovery and Biology (TD&B) is seeking a highly motivated Senior... ...Virology, or a related discipline with 1-2 years of relevant postdoctoral and/or industry research experience.Strong background in...For PostDocFull timeFlexible hours$127.12k - $171.99k
...modifying potential in patients.The proposal and advancement of drug discovery programs will be based on a sound and compelling scientific... ...metabolism and bone diseasePreferred Qualifications:PhD with postdoctoral experience in bone metabolism and metabolic disease (industry...For PostDocFull timeFlexible hours$140.12k - $189.58k
...this vital role you will provide scientific leadership for the discovery and preclinical development of next-generation therapeutics... ...evaluate novel therapeutic mechanisms and optimize candidate molecules.Design, oversee, and interpret in vitro and in vivo pharmacology...For PostDocFull timeFlexible hours$138.08k - $186.81k
...validation, and implementation of assays for the detection of binding and neutralizing anti-drug antibodies (ADAs & NAbs) for Amgen’s large molecule/protein therapeutics to support GLP preclinical and regulated clinical studies. Such molecules will inherently be diverse in...For PostDocFull timeFlexible hours$109.02k - $147.5k
...validation, and implementation of robust quantitative LC-MS/MS bioanalytical methods and experiments for small molecules and perform bioanalysis for discovery, GLP preclinical and regulated clinical studies.The position is lab-based, and additional responsibilities will...For PostDocFull timeContract workFlexible hours$126.07k - $170.56k
...is responsible for late-stage drug product formulation and fill/finish process development for various biological modalities (large molecule, RNA, virus). The Sr. Scientist will provide technical and project leadership while integrating information generated by multi-...For PostDocFull timeWorldwideFlexible hours- ...validation, and implementation of robust quantitative LC‑MS/MS bioanalytical methods and experiments for small molecules, and to perform bioanalysis for discovery, GLP preclinical and regulated clinical studies. The role is lab‑based and includes critical review and...For PostDocContract workFlexible hours
$90.44k - $122.36k
...oligonucleotides). The candidate is expected to have hands-on experience in formulation development and stability characterization of large molecule drug candidates to assess their critical quality attributes supporting diverse therapeutic areas. The candidate will be...Full timeFlexible hours- Amgen in Thousand Oaks is seeking a Senior Scientist in Functional Genomics to translate data into discovery, accelerating target discovery and prosecution through complex in vitro models. You will partner across therapeutic areas to advance discovery pipelines and contribute...
$173.99k - $235.4k
...Matter Expert (SME) on TSRS Teams Provide expertise to support discovery and development programs and partner with TSRS project team... ...safety pharmacology strategy across modalities, including small molecules, biologics, and emerging therapeutic approachesCoordinate investigative...For PostDocFull timeFlexible hours$126.07k - $170.56k
...vital role you will support Amgen’s diverse early-stage therapeutic portfolio by characterizing process and product properties of large-molecule drug candidates and assessing quality attributes of protein therapeutics across multiple pipeline areas. This role will provide...For PostDocFull timeFlexible hours$140.12k - $189.58k
...doLet’s do this. Let’s change the world. In this vital role you will combine experimental and computational strategies to accelerate discovery and development of innovative therapies. You will bring deep expertise across wet-lab biology and AI/ML-driven computational and...For PostDocFull timeFlexible hours- ...and collaboration across programs in oncology, inflammation, and rare disease. No direct reports are required. The role requires a PhD with extensive postdoctoral experience or equivalent, strong publication/patent record, and the ability to drive #J-18808-Ljbffr AmgenFor PostDoc
$143.53k - $194.18k
...modeling experience5 + years industry or relevant academic experience in pharmacometric analyses and/or applied bio-statistics of small molecules and/or biologics.Proficiency in modeling software (e. g. NONMEM, SAS, R/S-Plus, STAN, MATLABWhat you can expect of usAs we work to...For PostDocFull timeFlexible hours$130.38k - $176.4k
...results and communicate findings through technical reports, presentations, and team discussions.Collaborate with scientists across Discovery Research, Precision Medicine, Translational Safety and Risk Sciences, and other functional areas.Maintain accurate laboratory...For PostDocFull timeFlexible hours$129.23k - $174.84k
...Methodologies (NAMs) and broader translational safety initiatives across the organization. This role sits at the intersection of discovery biology, nonclinical safety, NAMs, and translational medicine, requiring strong technical expertise combined with scientific curiosity...For PostDocFull timeRemote workFlexible hours$126.07k - $170.56k
...and product development and drug substance and drug product analytical method development is a plus.Strong understanding of small molecule analysis, structure elucidation and solid-state characterization guided and informed by knowledge of organic chemistry.Experience...For PostDocFull timeContract workImmediate startFlexible hours$24.32 - $26 per hour
...attributes in product and process for late phase synthetic small molecule, synthetic oligonucleotide, synthetic peptide and/or antibody... ...analysis using Empower or similar LC platforms; experience with large molecule analysis is preferred. Develop, optimize, and...Hourly payFull timeLocal areaFlexible hours- Aequor in Thousand Oaks, CA is seeking an Associate Scientist for an onsite 12-month contract (W2). You will perform in vitro tissue culture experiments, plan and monitor studies, and organize data with minimal supervision to generate robust results. Day-to-day work includes...Contract work
- ...in vitro tissue culture experimentation and benchwork to support early discovery programs. Broadly, these experiments will test mechanisms, develop assays, and explore function of early lead molecules. Other responsibilities may include processing downstream rodent...Contract work
- Infotree Global Solutions seeks a biology-focused scientist to perform experiments, organize data and analyze results under minimal supervision. The role involves planning and monitoring experiments, translating literature methods to the lab, developing new protocols, and...
- ...portfolio projects across therapeutic modalities. The role focuses on formulation development and stability characterization of large molecule candidates, ensuring quality attributes support IND readiness. You will develop drug product formulations and provide...
- ...vital role you will support Amgen’s diverse early‑stage therapeutic portfolio by characterizing process and product properties of large‑molecule drug candidates and assessing the quality attributes of protein therapeutics across multiple pipeline areas. Responsibilities...For PostDocFlexible hours
- ...expression, purification, and characterization. We are responsible for the engineering, production, assessment, and final selection of large molecule drug candidates that advance to Process Development. Responsibilities Advancing our pipeline by purifying and characterizing...Remote workFlexible hours
- ...expression, purification, and characterization. We are responsible for the engineering, production, assessment, and final selection of large molecule drug candidates that advance to Process Development. In this role, you will support the purification of large molecule,...Full timeFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Postdoctoral Fellow - Large Molecule Discovery (LMD). Be the first to apply!

