Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Remote Principal Solution Software Engineer

Hcesquared

OUR COMPANY

HCEsquared® is a leading healthcare solutions platform developed by healthcare specialists for healthcare specialists to elevate patient care. We serve our community of clinicians by delivering practical clinical and non-clinical content through digital and in-person connections ​. We provide our clinicians with solutions to serve their patients through onsite and digital educational content based on the newest and best therapies and techniques from respected thought leaders in the field of dermatology as well as services to enhance their career trajectories. Our offerings have been proven to enhance clinician confidence, demonstrated by our exceptional audience and partner retention rates for our ecosystem . For more details on our clinician offerings and continuing medical education, please visit our portfolio companies on the  hcesquared.com website. Our conferences can be viewed at 

 

WHY JOIN HCESQUARED®?
At HCEsquared®, our mission is simple: elevate patient outcomes by elevating the people who deliver care. When you join us, you become part of a team that blends healthcare expertise, educational excellence, and a shared commitment to making a measurable impact.

Meaningful Work
Your contributions directly strengthen the skills and performance of healthcare professionals. Your work ultimately improves patient lives.

Growth-Driven Culture
We develop our people through coaching, stretch assignments, and opportunities to lead. Your professional growth isn’t a perk, it’s a priority.

Values-Led Teamwork
You’ll collaborate with high-performing colleagues who care about integrity and continuous improvement.

Empowered Innovation
We encourage new ideas and give you the autonomy to innovate and improve processes.

Flexibility With Accountability
Remote work creates the flexibility you need while maintaining the high expectations for   performance, communication, and ownership.

 

THE ESSENTIALS

This role is best suited for individuals who thrive in a fast-paced, entrepreneurial environment and bring a proven track record of delivering results through strong partnership and influence.


  • Vision – the ability to zoom out, define what “good” looks like, and clearly communicate that direction across and beyond the organization.

  • Strategic problem solving – the ability to translate vision into action by breaking complex opportunities or challenges into simple, executable strategies.

  • Grounded Leadership – the ability to lead with confidence in direction while demonstrating humility in execution, taking ownership, seeking input, and adapting as new information emerges.

  • Accountability and collaboration – the ability to take ownership of outcomes while motivating others to work effectively across the organization and setting clear expectations.

  • Grit – the willingness and ability to overcome challenges, move beyond ideas, and consistently drive results.


JOB DESCRIPTION

Title:  Principal Solution Software Engineer
Reporting To:  Chief Digital, Technology & Data Officer (CTDO)
Location: Remote (U.S.)
Applicants must be legally authorized to work in the United States. HCEsquared® does not sponsor or assume sponsorship of employment visas.

ROLE SUMMARY

We're hiring a Principal Solution Software Engineer to bridge product vision and engineering delivery on a platform built to scale across medical specialties.

HCEsquared® is a PE-backed healthcare education platform — currently focused on dermatology — that connects pharmaceutical sponsors to verified clinical outcomes and powers AI-driven content at scale. Our engineering teams, internal and contracted, need requirements translated into precise technical specifications before code is written. That translation is your job.

You will own the space between the whiteboard and the pull request: turning product requirements into technical designs, integrations into working systems, and ambiguous problems into solutions that ship. You catch design flaws before they become production incidents and make sure engineering always has what it needs to build with confidence.

We ship through AI-assisted development — person-agent pairs using tools like Claude Code. You'll be fluent in that model and help set the standard for how it's used.

ACCOUNTABILITY


  • Solutions meet documented requirements with zero critical post-deployment defects from design or requirements gaps

  • All platform integrations operational, documented, and maintainable

  • Specifications complete and feasibility assessed before any sprint commitment

  • Documentation, integration maps, and runbooks current at all times

  • Engineering teams always have what they need to build with confidence

  • Contribute to a reliable, scalable, integrated platform serving HCPs and pharmaceutical sponsors

RESPONSIBILITIES


  • Translate requirements into technical specifications. Partner with product, design, and commercial stakeholders to define the technical approach, assess feasibility, and document specs engineering can execute without ambiguity.

  • Design integration architectures for new platform capabilities and third-party systems — CRM, event management, marketing automation, CMS, LMS, and data platforms. Ensure every design fits the broader platform, AWS environment, and Snowflake data strategy, and extends across new specialty markets.

  • Own assigned solutions from design through production. Coordinate engineering teams, vendors, and stakeholders, and enforce a definition of done that covers code review, testing, analytics instrumentation, and documentation.

  • Lead technical design review. No significant feature or integration enters engineering without a validated prototype and reviewed specification.

  • Own third-party tool and API integrations across the platform — evaluate, define requirements, and keep them documented and maintainable.

  • Own the technical documentation layer: architecture diagrams, integration maps, API specs, and operational runbooks.

  • Provide build-vs-buy assessments for new tools and platform decisions, with evidence-based recommendations to the CTDO.

REQUIREMENTS


  • Demonstrated leadership essentials as described above

  • 4-year degree from an accredited academic institution 

  • 7+ years in solution engineering, technical product management, software architecture, or a senior IC engineering role

  • Proven ability to write precise technical specifications engineering can execute without architectural ambiguity — this is core to the role

  • Strong experience integrating third-party systems via REST APIs, webhooks, OAuth 2.0, and SAML 2.0 across a modern SaaS stack

  • Web application architecture fluency at the level of a senior technical reviewer — ideally Next.js or React with AWS-hosted backend services. You don't need to be the primary developer, but you must assess architectural decisions, review PRs meaningfully, and understand impacts on performance, cost, and data integrity

  • Integration and architecture experience with headless Next.js, CMS, LMS, CRM, marketing automation, and event management platforms — not just as a user

  • Strong QA, testing, and documentation discipline — runbooks, integration maps, and architecture diagrams are default deliverables

  • Comfort working in an AI-assisted development environment (GitHub Copilot, Claude Code, or equivalent) is expected. We ship through person-agent pairs and you'll help set the standard

  • Healthcare or regulated industry experience preferred; familiarity with HCP platforms, pharma compliance, or medical education tech is a differentiator. Experience building integrations that generalize across markets or specialty areas is a plus

 

SALARY & BENEFITS

This is an opportunity to do meaningful work, grow your impact, and continue developing your expertise within a high-performing, mission-driven organization.

Salary is commensurate with experience and qualifications. HCEsquared® offers a comprehensive benefits package designed to support the health, flexibility, and professional growth of our team, including:


  • Fully remote work environment with a flexible time off policy

  • Dedicated professional development support , including reimbursement for approved learning and development activities.

  • Comprehensive wellness benefits , including medical, vision, and dental coverage, with a significant portion of premiums subsidized for employees and eligible dependents, as well as access to HSA, FSA, and Dependent Care FSA plans

  • Employer-paid life insurance , short-term disability, and long-term disability coverage

  • 401(k) retirement plan with company matching

  • Cell phone reimbursement for business use

  • Home office stipend to support a productive remote setup

Vacancy posted 15 days ago
Similar jobs that could be interesting for youBased on the Remote Principal Solution Software Engineer in Toledo, OH vacancy
  •  ...HCEsquared® is a leading healthcare solutions platform developed by healthcare specialists...  ...Flexibility With Accountability Remote work creates the flexibility you...  .... JOB DESCRIPTION Title:  Principal Solution Software Engineer Reporting To:  Chief Digital,... 
    Remote work
    Temporary work
    Home office
    Flexible hours

    Hcesquared

    Honolulu, HI
    15 days ago
  • Providing technical leadership in a remote capacity, the full-time Principal Software Engineer will drive architectural excellence, mentor engineers, and influence...  ...complex production issues, implementing long-term solutions to prevent recurrence Required Qualifications... 
    Remote work

    VirtualVocations

    Montgomery, AL
    9 days ago
  •  ...many companies struggle with: maintaining software architectural excellence and agility...  ...and we need to answer with world-class engineering. We're building not just one product, but...  ...teams ~ Self-directed and effective in remote environments with at least 4 hours of overlap... 
    Remote work

    Opsmill

    Louisville, KY
    15 days ago
  • $130k - $200k

     ...Senior / Principal Flight Software Engineer – Space Systems *REMOTE* Working with a leading U.S. aerospace company looking to add Senior and Principal-level Flight Software Engineers to their satellite team. This is a hands-on role focused on building and testing... 
    Remote work

    Red Canyon Engineering & Software

    Madison, WI
    a month ago
  • $246k - $394k

     ...customers at scale. As a Senior Principal Engineer for GTM Experiences, you...  ...than disconnected point solutions. Partner with product, design...  ...~10+ years of experience in software engineering, with a strong...  ...our benefits at  . #LI-REMOTE The base salary range for... 
    Remote work
    Local area

    Toast

    Garland, TX
    15 days ago
  • $150k - $300k

     ...employees, and communities. The Role This is a top software engineer job that incorporates everything you’ve worked so hard for. And...  ..., such as variable bonus and/or stock bonus. \n #LI-Remote Veeva’s headquarters is located in the San Francisco Bay... 
    Remote work
    Work at office
    Local area
    Work from home
    Flexible hours

    Veeva Systems

    Detroit, MI
    15 days ago
  •  ...machine learning workloads. We’re looking for a Senior Principal Software Engineer to own and drive our feature store product. This is a unique...  ..., equity, and comprehensive benefits Flexible Work: Remote-friendly culture with flexibility to do your best work... 
    Remote work
    Local area
    Worldwide
    Flexible hours

    Redis

    Lincoln, NE
    15 days ago
  • $140k - $200k

     ...developer experience. We’re looking for a Principal Engineer with deep expertise in systems...  ...+ years of experience building systems software in C/C++ or Rust (Go experience a plus)...  ...powerful for developers everywhere. LI-remote The typical starting salary for this... 
    Remote work
    Local area
    Home office
    Flexible hours

    Clickhouse

    Plano, TX
    15 days ago
  • $197k - $207k

    Job title: Principal Software Engineer (REF# AT0630) Hours: Full Time Company name: Convera USA LLC Worksite: 7979 E Tufts Ave., Suite 200, Denver CO 80237. Position allows 100% remote work from anywhere in the U.S. and reports to Convera’s HQ. Job Duties: Lead... 
    Remote work

    Convera

    Baton Rouge, LA
    2 days ago
  • $180k - $210k

     .... We are seeking a DevOps Engineer to help design, build, and operate...  ...ready to scale. This is a remote position based in the United...  ...how the infrastructure solutions evolve to match the requirements...  ...systems, with clear senior or principal-level impact ~ Experience designing... 
    Remote work
    Local area
    Flexible hours

    Utilidata

    Garland, TX
    a month ago
  •  ...efficiency. Serve as a role model for junior engineers through mentoring and direct education....  ...Description We are looking for a Principal Software Engineer to work on our various systems...  ...Full Time Office Location Remote Job  You can live anywhere in Japan... 
    Remote work
    Work at office
    Visa sponsorship
    Relocation package
    Flexible hours

    Paypay

    Hialeah, FL
    15 days ago
  • $185k - $193k

     ...Principal Software Engineer / Full Stack AI Builder · Spec-Driven Development · Agentic Orchestration     We're looking for a Principal Engineer...  ...light industrial staffing company and a broad workforce solutions provider, our digital-enabled approach to staffing is... 
    Remote work
    Local area

    Employbridge Career

    Fremont, CA
    8 days ago
  • $313.8k

     ...buyer experience. About the Role We’re looking for a Principal Software Engineer to help shape the technical future of Commerce Hub. This...  ...we value both flexibility and connection. Whether you’re a Remote employee or work from the Office, we want you to start your... 
    Remote work
    Contract work
    Live out
    Work at office

    Hubspot

    Columbus, OH
    15 days ago
  • $215.2k - $240k

     ...Principal Software Engineer (Hybrid - 1-2 days per week onsite)  Overview: As a Principal Software...  ...platform to provide end-to-end SaaS solutions for the cannabis supply chain, it...  ..., California, WM Technology supports remote work for all eligible employees. Visit... 
    Remote work
    Temporary work
    Work experience placement
    Casual work
    Local area
    Worldwide
    Flexible hours
    Night shift
    2 days per week
    1 day per week

    Weedmaps

    Arlington, TX
    15 days ago
  • $200k - $240k

     ...journey, come join us and let's Tango! We are looking for a Principal Software Engineer to join our dynamic and growing Engineering team....  ...support your well-being. Flexible Work Environment  Whether remote, hybrid, or in-office, we support work arrangements that... 
    Remote work
    Work at office
    Visa sponsorship
    Work visa
    Flexible hours

    Tango

    Virginia Beach, VA
    15 days ago
  •  ...disrupting the criminal underground. SpyCloud’s solutions thwart cyberattacks and protect more...  ..., look no further! We are seeking a Principal Engineer to lead the hands-on architecture and...  ...in South Austin, flexible and remote-friendly work options, and competitive... 
    Remote work
    Contract work
    Temporary work
    Local area
    Worldwide
    Visa sponsorship
    Flexible hours

    Spycloud

    Arlington, TX
    a month ago
  • $165k - $180k

     ...fully comprehensive end-to-end homecare solution to help people who are aging or have...  ...organizations, and states. The Principal Software Engineer will play a critical role in designing...  ...essential functions. This is a fully remote opportunity for candidates located in... 
    Remote work
    Local area
    Night shift

    Hhaexchange

    Hialeah, FL
    8 days ago
  •  ...A Principal Software Engineer leads and supports complex software initiatives, driving high-level technical decisions and providing guidance throughout the software development lifecycle. You will leverage deep technical expertise to shape architectural design, evolve... 
    Remote work
    Shift work
    Weekend work

    Mlabs

    Omaha, NE
    15 days ago
  • $221k - $299k

     ...Our Winning Culture is the engine that drives our teams of innovators...  .... Job Title Principal Software Engineer, Security...  ...RDMBS systems. Find and propose solutions to improve Anaplan's products...  ...Senior Software Engineers. Remote work is permissible within a... 
    Remote work

    Anaplan Inc.

    Gilbert, AZ
    4 days ago
  • $205.2k - $360.8k

     ...Job Description Role: Senior Principal, AI Software Engineer– Agentic & Industry Solutions Location- TX (Remote) Role Type: Fulltime Salary: $205200.00 - $360800.00 per yearly   Job Description   Be the one building AI-powered experiences where they... 
    Remote work
    Work from home
    Flexible hours

    Tms, Llc

    Saint Louis, MO
    22 hours ago
  •  ...Principal Software Engineer - Backend We’re looking for a Principal level Backend Engineer to help us build and polish the Post.News web/mobile applications. This role is Remote within the U.S. We are not able to sponsor visas at this time.  About us Meet... 
    Remote work
    Visa sponsorship

    Post.

    Bakersfield, CA
    a month ago
  •  ...Description We are looking for a Principal Software Engineer to work for our client. The ideal...  ...qualifications outlined below. This is a remote position , but candidates must...  ...-to-end delivery of complex software solutions Act as technical authority across... 
    Remote work

    Ringside Talent Acquisition Partners

    Worthington, OH
    1 day ago
  • $160k - $165k

     ...Senior Software Engineer **This position is primarily remote. There may be rare meeting in the downtown DC area.** JCDS is hiring a senior software engineer...  ..., development, and delivery of technology-based solutions. To be successful as a senior software engineer, you... 
    Remote work
    Work from home
    Flexible hours

    JCD Staffing

    United States
    4 days ago
  •  ...Principal Software Engineer Location: Boston, MA; NC; Salt Lake City, UT; Smithfield, RI/Remote Duration: Long Term Required Skills: Java, J2EE, Spring Boot, REST, Microservices, API development Preferred Skills: Kafka, UI, Spark, Docker, React, Kubernetes... 
    Remote work

    Samprasoft

    United States
    4 days ago
  •  ...culture. We are a distributed team with remote employees across every US time zone, as...  .... Who You Are You are a Principal Engineer who is both AI-native and relentlessly...  ...launch large-scale and/or highly complex software that requires members of multiple teams... 
    Remote work
    Sleeping nights

    Brightwheel

    Albuquerque, NM
    2 days ago
  •  ...Principal Software Development Engineer At Shakudo, we're building the world's first operating system for data and AI—a unified platform that streamlines...  ..., moving across the stack, and delivering high-impact solutions that showcase what's possible on Shakudo. What You'... 
    Remote work

    Shakudo

    United States
    21 hours ago
  •  ...Senior Software Engineer For Ruby On Rails A Senior Software Engineer for Ruby on Rails is an associate at Creative Chaos who is mainly responsible for developing server applications of various software platforms including but not limited to writing Restful APIs to... 
    Remote work

    Creative Chaos

    United States
    2 days ago
  • $162k - $258.75k

     ...About the Principal Software Engineer, Backend at Headspace: At Headspace, you’ll be working on a...  ...issues and architecting platform-level solutions with reusability and extensibility in...  ...Location: We are currently hiring this role remotely unless SF based. Candidates must... 
    Remote work
    Currently hiring
    Work at office
    Local area
    3 days per week

    The Headspace

    Seattle, WA
    a month ago
  • $145k - $165k

     ...and confidence. Feathr's software marketing platform equips...  ...to the right place. Principal Backend Software Engineer: Compensation Range: $1...  ...to 12% Benefits: Fully remote, Health/dental/vision insurance...  ...and design technical solutions, collaborate with your engineering... 
    Remote work
    Work experience placement
    Home office

    Feathr

    Fresno, CA
    a month ago
  •  ...Principal Software Engineer For Ai Team At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don't just use tools... 
    Remote work
    Flexible hours

    Snowflake Computing

    United States
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Remote Principal Solution Software Engineer. Be the first to apply!