Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Principal Scientist, Immune Cell Depletion Discovery Group, Immunology Discovery Research

BioSpace

Job Description The Immunology Discovery Therapeutic Area is seeking an accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune Reset Therapeutics Discovery team based in Cambridge MA. In this role you will lead a multidisciplinary team of highly talented scientists with experimental, technical and scientific expertise in cellular depletion approaches. The candidate should have a demonstratable track‑record in this scientific discipline alongside a strong knowledge of preclinical drug discovery spanning target discovery / validation through to GLP toxicology phases. The ability to effectively collaborate and deliver results across multidisciplinary line functions both internally and with external leading experts is required. Proven expertise leading preclinical drug discovery programs leveraging cellular depletion approaches in autoimmune disease is an advantage. Applicants should have a strong publication record and have proven experience in leading (managing) & developing bench-based scientists. Key Responsibilities Lead the Immune Cell Depletion Group within Immunology Discovery. Responsible for refining the strategy and biology focus within this area to support and advance the portfolio Provide biology expertise to internal teams that helps pave the way for next‑generation therapies that leverage cell depletion approaches to develop next generation therapies for rheumatological, dermatological, gastroenterological and respiratory diseases Key member of the Immune Reset Therapeutics Discovery Leadership Team, to support advancement of Immune Tolerance biology into the drug discovery pipeline Proven experience in managing, growing and developing highly talented scientists Drive performance by Leading from the Bench. Including the ability to design and execute on key experiments to inform decision‑points (GO / NO‑GO) at critical stages of projects Proven track record of leading and influencing early to late‑stage discovery programs Deep immunology expertise, with emphasis on understanding how cell depletion approaches can potentially raise the treatment ceiling for patients with autoimmune disease Help develop and execute a strategy in alignment with functional goals and key scientific objectives in discovery immunology research. Highly collaborative, team‑oriented, and considerate of the needs of others Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners. Highly organized & self‑directed, capable of leading multiple complex research programs in parallel. Excellent written and verbal communication is required as well as critical evaluation and data‑driven decision making. Provide expert advice and share knowledge with direct reports, peers, and senior leadership Establish and manage external collaborations with leading research labs around the world. Includes attendance / presentation at conferences and submission of publications. Qualifications 18 + (BS), 16 + (MS), or 10 + (PhD) years of related work experience in academia, biotech or pharma Extensive experience in immunology drug discovery within a high‑caliber research environment with 6+ years of related work experience in biotech or pharma Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued. Willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view Ability to work, influence, lead and deliver results in cross‑functional teams Excellent written, presentation and interpersonal communication skills. Ability to be effective in a highly collaborative environment. Key AbbVie Competencies Builds strong relationships with peers and cross‑functionally with partners outside of the team to enable high performance. Learns fast, grasps the essence and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Benefits The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical / dental / vision insurance and 401(k) to eligible employees. This job is eligible to participate in our long‑term incentive programs. Equal Opportunity Employer AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only – to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr BioSpace

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Senior Principal Scientist, Immune Cell Depletion Discovery Group, Immunology Discovery Research in Cambridge, MA vacancy
  •  ...therapeutic areas including immunology, oncology and...  ...The Immunology Discovery Therapeutic Area...  ...accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune...  ...immunology research. Highly...  ...reports, peers, and senior leadership Establish... 
    Principal
    Senior
    Full time
    Work experience placement
    Local area

    AbbVie

    Cambridge, MA
    17 hours ago
  •  ...highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological functional assays for analyzing genetically...  ...functional assays to assess immune cell activation, anti‑tumor... 
    Senior

    Regeneron Pharmaceuticals, Inc

    Cambridge, MA
    2 days ago
  • $80.3k - $131.1k

     ...highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological function assays for analyzing genetically...  ...functional assays to assess immune cell activation, anti‑tumor... 
    Senior

    Regeneron Pharmaceuticals, Inc (USA)

    Cambridge, MA
    17 hours ago
  • $130.8k - $209.4k

     ...RoleThe Therapeutics Research group at Moderna is...  ...highly motivated Senior Scientist to implement scalable...  ...platforms for T cell repertoire...  ...antigen-specific TCR discovery and functional validation...  ...in T cell immunology, antigen-specific...  ...complex immune profiling results... 
    Senior
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    4 days ago
  • $148k - $203.5k

     ...spectrum of drug discovery, development,...  ...highly collaborative Senior Principal Scientist, In Vitro...  ...validating, and applying cell-based assays...  ...areas spanning Immunology, Oncology, and Metabolic...  ...entrepreneurial research environment.Key...  ...primary immune cells, engineered... 
    Principal
    Senior

    Seres Therapeutics

    Cambridge, MA
    1 day ago
  •  ...seeking an ambitious, creative, and talented Discovery Immunology Senior Scientist or Principal Scientist to join our research team. You will be part of the team responsible...  ...will scale efficiently. Manage outsourced cell biology and in vivo biology resources, establishing... 
    Senior

    Flagship Pioneering

    Cambridge, MA
    4 days ago
  • $142.5k - $256.5k

     ...accomplished and highly motivated Principal Scientist to join the Antibody Discovery team within Therapeutics Research. Therapeutics Research...  ...and antigen strategy, immunization and B cell discovery campaign design...  ...Qualifications)PhD in immunology, molecular biology, biochemistry... 
    Principal
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    1 day ago
  • Two River is seeking a creative cell biologist to join the discovery research team in Cambridge, MA. You will design and execute primary immune cell-based assays to profile multi-specific biologics and generate high-quality data for AI-assisted discovery. The role requires... 

    Two River

    Cambridge, MA
    3 days ago
  • $98.7k - $183.3k

     ...SummaryBiomedical Research (BR) is the...  ...We are seeking a Senior Scientist to bring deep molecular...  ...high-impact drug discovery programs.Job...  ...Discovery Biology group in Cambridge is seeking...  ...last 2 years) in Cell Biology,...  ...Ethics, Gene Therapy, Immunology, Machine Learning... 
    Senior
    Full time

    Novartis

    Cambridge, MA
    17 hours ago
  •  ...accomplished and highly motivated Principal Scientist to join the Antibody Discovery team within Therapeutics Research. Therapeutics Research...  ...and antigen strategy, immunization and B cell discovery campaign design...  ...Qualifications) PhD in immunology, molecular biology,... 
    Principal

    PVH (Tommy Hilfiger/Calvin Klein)

    Cambridge, MA
    4 days ago
  • Moderna is seeking a Senior Scientist to implement scalable platforms for T cell repertoire analysis from patient samples. You...  ...and antigen-specific TCR discovery across oncology and autoimmune indications...  ...medicine teams to translate immune profiling into actionable... 
    Senior

    BioSpace

    Cambridge, MA
    7 hours ago
  • Moderna is seeking a Senior Scientist to implement scalable platforms for T cell repertoire analysis and TCR discovery from patient samples. You will...  ...teams to translate immune profiling results into therapeutic...  ...role requires a PhD in immunology or related field with 2+... 
    Senior

    Moderna Therapeutics

    Cambridge, MA
    3 days ago
  •  ...RNA‑LNP‑based cell therapies for the...  ...motivated scientist to lead the development...  ...cell‑based and immunology assays that...  ...guide therapeutic discovery and development...  ...an experienced Senior Scientist or...  ...particular emphasis on immune cell...  ...scientifically rigorous research environment.... 
    Senior

    C10 Labs

    Cambridge, MA
    4 days ago
  • $286.9k

    Job DescriptionSenior Principal Scientist (Senior Medical Director)...  ...ImmunologyTranslational Medicine in our Research & Development...  ...of preclinical discovery into compounds ready...  ...a position in our group. Please note that...  ..., with a focus on Immunology R&D, as well as clinical... 
    Principal
    Senior
    Full time
    For contractors
    Local area
    Worldwide
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Boston, MA
    3 days ago
  • $105.04k - $127.29k

    ## Senior Associate Scientist, In Vivo Pharmacology, Oncology Discovery BiologyCambridge Crossing - MA - USFind out...  ...breakthroughs in cell therapy, this is work...  ...The Oncology Thematic Research Center at BMS is a key...  ...Pharmacology and In Vivo Biology group at Bristol-Myers... 
    Senior
    Hourly pay
    Full time
    Temporary work
    Part time
    For contractors
    Summer work
    Live in
    Work at office
    Local area
    Remote work
    Flexible hours
    Shift work

    Bristol-Myers Squibb

    Cambridge, MA
    2 days ago
  • $126k - $181.5k

     ...of small molecule drug discovery. FL129 is developing a...  ...a team of top-tier scientists to build this powerful...  ...highly collaborative Senior Scientist to join FL12...  ...experience adapting screens to cell- or surface-displayed...  ...managing contract research organizations (CROs).... 
    Senior
    Contract work

    Seres Therapeutics

    Cambridge, MA
    17 hours ago
  •  ...staffingfuture.comOverviewWe are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts. We are...  ...Protein Engineering, Molecular Biology, Biochemistry, Immunology, Cancer Biology, or a closely related field, with 2+ years... 
    Principal
    Senior

    Planet Pharma

    Boston, MA
    2 days ago
  • $131k - $146k

     ...different tissues, organs and cell types. Prime Medicine is...  ...areas of focus: hematology, immunology & oncology, liver and lung....  ...an exceptionally driven, discovery-minded Scientist to join our Platform Technology...  ...to other platform-level research challenges. Leading discovery... 
    Full time
    Temporary work

    Prime Medicine

    Cambridge, MA
    4 days ago
  • Moderna Therapeutics is seeking a Principal Scientist to lead integrated antibody discovery and engineering campaigns...  ...programs. You will oversee immunization design, B cell discovery, display‑based engineering...  ...and computational biology groups to advance programs. The role... 
    Senior

    Moderna Therapeutics

    Cambridge, MA
    4 days ago
  • Moderna seeks a Senior Scientist to implement scalable platforms for T cell repertoire analysis from patient samples and disease-relevant data. You will drive T cell profiling, TCR discovery, and functional validation across oncology, autoimmunity, and other areas to inform... 
    Senior

    Initial Therapeutics, Inc.

    Cambridge, MA
    2 days ago
  • $148.5k - $214.5k

    Job title: Senior Principal ScientistLocation:...  ...Senior Principal Scientist to spearhead...  ...expansion of our mast cell disorders Research & Development...  ...and related immune disorders in the...  ....Drive early discovery initiatives by...  ...biology, hematology, immunology, or related... 
    Principal
    Senior
    Full time

    Sanofi

    Cambridge, MA
    17 hours ago
  • Simcere Pharmaceutical Group is an innovation-driven pharmaceutical...  ...is dedicated to cutting‑edge research aligned with the company...  ...join our dynamic Neuroscience Discovery team. This role focuses on investigating...  ...an independent bench scientist and strategic thinker who can... 
    Senior

    Simcere Pharmaceutical Group

    Cambridge, MA
    1 day ago
  •  ...motivated Scientistto join our Discovery BiologyteamlocatedinWatertown,...  ...experienced and self-directed Senior Scientist to build proteomics capabilities within our research organization. This is a hands-...  ...new methodologies into the group proactively. What you will need... 
    Senior
    Shift work

    Socket.dev

    Watertown, MA
    1 day ago
  •  ...incubator. From discovery to delivery,...  ...experienced scientists, operators,...  ...TechAtlas internal research division, and...  ...Scientist/Senior Scientist in Immunology to join our...  ...implement robust cell‑based and...  ...assays for type 2 immunity mechanisms,...  ...protected group status under... 
    Senior

    Raven

    Cambridge, MA
    4 days ago
  •  ...Myers Squibb is seeking a highly motivated Senior Associate Scientist to join the Discovery Biotherapeutics team in Cambridge, MA. This...  ...ML, binder discovery, and functional assay groups to accelerate early biologics research. #J-18808-Ljbffr Bristol Myers Squibb EU Policy
    Senior

    Bristol Myers Squibb EU Policy

    Cambridge, MA
    4 days ago
  • $119.7k - $222.3k

     ...Experience in late discovery into clinical...  ...and/or cell therapies across...  ...including oncology, immunology,...  ...candidates across Research Development and...  ...considered for Principal Scientist II. 4+ years of...  ...considered for Senior Principal Scientist...  ...:The Novartis Group of Companies... 
    Principal
    Senior
    Full time

    Novartis

    Cambridge, MA
    2 days ago
  • $126k - $181.5k

    Senior Scientist, Discovery Technologies Cambridge, MA USA What if… you could join an organization that...  ...including experience adapting screens to cell- or surface-displayed protein targets....  .... Experience managing contract research organizations (CROs). Nice to have: cheminformatics... 
    Senior
    Contract work

    Flagship Pioneering

    Cambridge, MA
    1 day ago
  •  ...product innovation through the discovery and development of new...  ...THE ROLE We are seeking a Senior Scientist to own translational biology...  ...and wellness industry. Lead research programs focused on new molecule...  ...mechanistic de-risking using cell-based, biochemical,... 
    Senior
    Work at office

    ODDITY LABS

    Cambridge, MA
    4 days ago
  • Regeneron is seeking a Senior Associate Scientist to join the discovery research team. You will perform immunological functional assays on genetically engineered human T cells (CAR‑T or TCR T cells) to inform preclinical programs and regulatory submissions. The role is... 
    Senior

    BioSpace

    Cambridge, MA
    4 days ago
  • $144.8k - $227.9k

     ...motivated-Associate Principal Scientist-to join our Genome Science research team in Cambridge...  ...stem cell models-in collaboration with the Discovery Immunology Therapeutic Area....  ...multidisciplinary groups, including Discovery...  ...audiences, including senior leadership. Preferred... 
    Principal
    Full time
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    Cambridge, MA
    4 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Principal Scientist, Immune Cell Depletion Discovery Group, Immunology Discovery Research. Be the first to apply!