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Senior Medical Science Liaison, Southeast (Multiple Territories) New United States - Remote

$190k - $220k

Praxis Precision Medicines, Inc.

Senior Medical Science Liaison, Southeast (Multiple Territories)

United States - Remote

Location: This position may be performed remotely with the required ability to travel up to 60–80%, as needed.

  • The Virginias
  • North Carolina
  • South Carolina
  • North Florida
  • South Florida

Position Summary:

Praxis is seeking a field-based Senior Medical Science Liaisons (MSL) to support prelaunch and launch activities. This role will focus on building trusted relationships with investigators and key stakeholders, delivering high-quality scientific exchange, and ensuring clinical and account readiness in advance of and following potential approval.

You will play a critical role in translating clinical data into meaningful insights for the field, educating healthcare professionals on disease state and emerging data, and identifying opportunities and barriers that may impact adoption. Working cross-functionally with Medical, Clinical Development, and Commercial teams, you will help shape and execute field strategy in a dynamic, fast-moving launch environment.

This is not a passive, reactive role – you are expected to operate with a high degree of ownership, proactively generate insights, and influence the field through credible, science-driven engagement.

We are open to hiring across levels and seek individuals who can operate independently in the field – whether developing into the role or already leading at a high level. Leveling will reflect experience, judgment, and the ability to drive impact in a prelaunch/launch setting.

Success in this role requires strong clinical credibility, excellent communication skills, strategic thinking, and comfort operating autonomously in a fast-paced environment.

Primary Responsibilities:

  • Serve as the primary field-based scientific partner to investigators and key stakeholders, building trusted relationships to support prelaunch readiness and successful product adoption.
  • Deliver high-quality scientific exchange on disease state, clinical data, and the ulixacaltimide profile, ensuring clear understanding of its potential role in treatment.
  • Educate and prepare clinical sites and healthcare providers for launch, including patient identification, treatment considerations, and integration into clinical practice.
  • Proactively gather, synthesize, and communicate field insights (e.g., treatment paradigms, barriers to adoption, unmet needs) to inform medical and cross-functional strategy.
  • Identify and engage key opinion leaders (KOLs) and emerging influencers, supporting the development of advocacy and scientific engagement strategies.
  • Partner cross-functionally with Medical, Clinical Development, Market Access, and Commercial teams to align on and execute field strategy.
  • Represent Praxis at scientific congresses and advisory engagements, translating external insights into actionable recommendations.
  • Maintain deep expertise in CNS/neurology, including evolving treatment landscapes and competitive developments, and apply insights to field strategy.
  • Ensure all field activities are conducted in compliance with regulatory requirements, GCP standards (as applicable), and Praxis policies and SOPs.

Qualifications and Key Success Factors:

  • Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN)
  • Experience in medical affairs, clinical research, clinical care, or field-based roles within biotech/pharma
  • Demonstrated ability to interpret and communicate complex scientific and clinical data with clarity and credibility to diverse stakeholders
  • Strong ownership mindset with the ability to operate independently, navigate ambiguity, and drive impact in a dynamic, prelaunch/launch environment
  • Proven ability to build and maintain trusted relationships with healthcare professionals, including investigators and key opinion leaders
  • Experience gathering and translating field insights into actionable recommendations for cross-functional teams
  • Ability to manage multiple priorities with strong organizational skills, attention to detail, and consistent follow-through
  • Willingness and ability to travel extensively (~60–80%) in a field-based role
  • Experience in neurology or CNS disorders preferred
  • Experience within market access/payor landscape is preferred
  • Candidates with prior field-based experience and a demonstrated track record of independently driving scientific engagement, shaping clinical perspectives, and contributing to successful pre-launch and launch activities will be considered at a higher level.

$190,000 - $220,000 USD

Compensation & Benefits

At Praxis, we believe that taking care of our people (and

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust , Ownership , Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE ® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Praxis Precision Medicines, Inc. ’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

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