Clinical Research Nurse

Job Title: Clinical Research Nurse III

Job Description

This Clinical Research Nurse III role combines advanced clinical nursing practice with comprehensive coordination of oncology clinical trials. The position focuses on patient-facing care, subject recruitment and enrollment, consistent study implementation, meticulous data management, and strict adherence to regulatory and reporting requirements. The nurse supports cutting-edge research in a collaborative environment, working closely with experienced physicians and a multidisciplinary team while contributing to innovative therapies and improved patient outcomes.

Responsibilities

• Perform core clinical nursing duties in support of oncology clinical research studies, ensuring safe, compassionate, and evidence-based patient care.

• Manage subject recruitment, including identifying potential participants, conducting screening procedures, and assessing eligibility according to study protocols.

• Obtain informed consent from prospective participants, clearly explaining study objectives, procedures, risks, and benefits, and ensuring understanding before enrollment.

• Support and oversee participant enrollment into clinical trials, coordinating all required baseline and follow-up assessments in accordance with protocol timelines.

• Collect and document clinical information and research data from study participants accurately and consistently, using established data collection tools and systems.

• Conduct detailed chart reviews to verify clinical information, confirm eligibility, and ensure data completeness and accuracy.

• Monitor participants for adverse events, document findings thoroughly, and perform adverse event reporting in accordance with Good Clinical Practice (GCP), institutional policies, and regulatory requirements.

• Provide patient education about research studies, including visit schedules, procedures, potential side effects, and adherence requirements, reinforcing information throughout the trial.

• Coordinate day-to-day study operations to ensure consistent implementation of study protocols, including scheduling visits, tests, and procedures.

• Maintain data integrity by entering, updating, and verifying information in electronic systems, including Epic and other research databases, and resolving discrepancies promptly.

• Ensure compliance with regulatory requirements and reporting obligations, including adherence to GCP guidelines and institutional and sponsor policies.

• Interact with consortium members and external partners, fostering effective communication and collaboration across participating institutions.

• Organize and coordinate meetings with consortium and study team members, including scheduling, preparing agendas, and ensuring appropriate participation.

• Track and record study progress, including enrollment metrics, participant status, and key milestones, and communicate updates to stakeholders.

• Schedule study-related meetings, record detailed minutes, and distribute documentation to relevant parties to ensure clear communication and follow-up on action items.

• Collaborate closely with the genitourinary (GU) research team, supporting their portfolio of studies and contributing to team-based problem-solving and process improvement.

• Assist with or provide leadership in aspects of study management as needed, drawing on prior management experience to support junior staff and streamline workflows.

• Contribute to a culture of continuous learning and professional development by engaging in training, staying current on research protocols, and sharing best practices with colleagues.

Essential Skills

• Active Registered Nurse (RN) license in the state of Pennsylvania (PA RN License).

• Nursing Diploma or Associate’s Degree in Nursing, with the ability to practice as a registered nurse.

• Minimum of 2 years of overall professional experience as a registered nurse.

• Minimum of 1 year of RN clinical experience providing direct patient care.

• Minimum of 1 year of clinical research experience, preferably in a research center or similar setting.

• Demonstrated experience in clinical research coordination, including patient recruitment, screening, and enrollment into clinical trials.

• Proficiency in collecting and documenting clinical information and research data from study participants with high accuracy.

• Experience conducting chart reviews to validate eligibility criteria and ensure data completeness.

• Competence in adverse event identification, documentation, and reporting in accordance with regulatory and institutional requirements.

• Working knowledge of oncology clinical care and oncology research workflows.

• Familiarity with Good Clinical Practice (GCP) guidelines and their application in clinical research.

• Ability to provide clear, empathetic patient education about research studies, including informed consent processes.

• Proficiency with Epic or similar electronic medical record systems for clinical documentation and data retrieval.

• Strong organizational and time-management skills, with the ability to manage multiple studies, tasks, and timelines concurrently.

• Effective verbal and written communication skills to interact with patients, study teams, and consortium members.

• Attention to detail and commitment to maintaining data integrity and regulatory compliance.

Additional Skills & Qualifications

• Bachelor of Science in Nursing (BSN) preferred.

• Some prior management or supervisory experience preferred, particularly in a clinical or research environment.

• Experience working within pharmaceutical-sponsored trials or industry-partnered research is beneficial.

• Background in oncology research, especially in genitourinary (GU) oncology, is advantageous.

• Experience working in a research center environment, including collaboration with multidisciplinary teams.

• Strong interpersonal skills and the ability to build rapport with patients, families, and colleagues.

• Demonstrated ability to participate in or facilitate meetings, including preparing agendas and recording minutes.

• Interest in professional growth and ongoing development within clinical research and nursing practice.

Work Environment

This role operates in a mixed office and hospital-based environment, providing exposure to both direct patient care settings and administrative research functions. The nurse works closely with physicians and a multidisciplinary research team on cutting-edge clinical trials, particularly within oncology and genitourinary (GU) research. Daily work involves the use of Epic electronic medical records, research databases, and standard clinical and office equipment. After approximately 60 days of training, the position may offer the flexibility to work from home one to two days per week, depending on study needs and operational requirements, with the understanding that remote work frequency may fluctuate. The culture emphasizes professional growth, with opportunities for advancement, tuition reimbursement upon conversion, and access to low-cost health benefits. The environment values collaboration, continuous learning, and participation in innovative research that advances patient care.

Job Type & Location

This is a Contract to Hire position based out of Philadelphia, PA.

Pay and Benefits

The pay range for this position is $35.00 - $45.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a hybrid position in Philadelphia,PA.

Application Deadline

This position is anticipated to close on Jul 20, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email View email address on click.appcast.io for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.